Microrna
Tetrandrine induces microRNA differential expression in human hypertrophic scar fibroblasts in vitro
Authors: Tetrandrine induces microRNA differential expression in human hypertrophic scar fibroblasts in vitro
MicroRNAs (miRNAs) have recently been shown to play a role in normal wound healing process. miRNAs may be linked to pathologic wound healing and closely related to the formation of hypertrophic scars. This study aimed to explore the effects of tetrandrine on the miRNA expression profile in human hypertrophic scar fibroblasts (HSFs) in vitro. HSFs were ran.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017288
- DOI:
- 10.4238/gmr.15017288
Functional polymorphisms in microRNA gene and hepatitis B risk among Asian population:a meta-analysis
Authors: G.Q. Zhou, H. Meng, J.R. Wang, F.X. Sun, X.J. Wang, R.B. Wang and X.B. Wang
Genetic mutations in microRNA gene can alter expression, which may interact to increase the risk of developing various diseases, including hepatitis B. However, published results are inconclusive or ambiguous. The aim of this review and meta-analysis is to more precisely estimate the association between polymorphisms in microRNA genes and hepatitis B risk.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.9
- DOI:
- 10.4238/2015.May.11.9
Identification of highly expressed host microRNAs that respond to white spot syndrome virus infection in the Pacific white shrimp Litopenaeus vannamei (Penaeidae)
Authors: D.G. Zeng, X.L. Chen, D.X. Xie, Y.Z. Zhao, Q. Yang, H. Wang, Y.M. Li and X.H. Chen
MicroRNAs (miRNAs) are known to play an important role in regulating both adaptive and innate immunity. Pacific white shrimp (Litopenaeus vannamei) is the most widely farmed crustacean species in the world. However, little is known about the role miRNAs play in shrimp immunity. To understand the impact of viral infection on miRNA expression in shrimp, we .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.14
- DOI:
- 10.4238/2015.May.11.14
Serum microRNA expression in pregnancies with preeclampsia
Authors: T. Gunel, Y.G. Zeybek, P. Ak�§akaya, I. Kalelio��lu, A. Benian, H. Ermis and K. Ayd�±nl�±
Preeclampsia continues to be a mortal disease of pregnant women throughout the world. Recently, geneticists, allied with obstetricians, have opened new frontiers. MicroRNAs (miRNAs) are members of a class of small, noncoding RNA molecules. They are critical posttranscriptional regulators of gene expression. We extracted circul.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.8.5
- DOI:
- 10.4238/2011.November.8.5
Aluminum triggers broad changes in microRNA expression in rice roots
Authors: J.C. Lima, R.A. Arenhart, M. Margis-Pinheiro and R. Margis
MicroRNAs are small 21-nucleotide RNA molecules with regulatory roles in development and in response to stress. Expression of some plant miRNAs has been specifically associated with responses to abiotic stresses caused by cold, light, iron, and copper ions. In acid soils, aluminum solubility increases, thereby causing severe d.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.10.4
- DOI:
- 10.4238/2011.November.10.4
MicroRNAs function primarily in the pathogenesis of human anencephalyvia the mitogen-activated protein kinase signaling pathway
Authors: W.D. Zhang, X. Yu, X. Fu, S. Huang, S.J. Jin, Q. Ning and X.P. Luo
Anencephaly is one of the most serious forms of neural tube defects (NTDs), a group of congenital central nervous system (CNS) malformations. MicroRNAs (miRNAs) are involved in diverse biological processes via the post-transcriptional regulation of target mRNAs. Although miRNAs play important roles in the development of mammal.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.20.3
- DOI:
- 10.4238/2014.February.20.3
Characterization of microRNAs and their target genes associated with transcriptomic changes in gamma-irradiated Arabidopsis
Authors: J.H. Kim, Y.S. Go, J.K. Kim and B.Y. Chung
MicroRNAs (miRNAs) regulate gene expression in response to biotic and abiotic stress in plants. We investigated gamma-ray-responsive miRNAs in Arabidopsis wild-type and cmt3-11t mutant plants using miRNA microarray analysis. miRNA expression was differentiated between the wild-type and cmt3-11t mutants. miR164a, miR169d, miR169h, miR172b*, and miR403 were.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038386
- DOI:
- 10.4238/gmr.15038386
Functional polymorphisms in microRNAs and susceptibility to liver cancer: a meta-analysis and meta-regression
Authors: B.S. Wang, Z. Liu, W.X. Xu and S.L. Sun
MicroRNAs (miRNAs) are small non-coding RNA molecules that play a fundamental role in controlling a variety of biological functions. Emerging evidence has shown that common genetic polymorphisms in miRNAs may be associated with the development of liver cancer; however, several individually published studies showed inconclusive.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.22
- DOI:
- 10.4238/2014.July.24.22
Expressional analysis of immune-related miRNAs in breast milk
Authors: R.S. Na, G.X. E, W. Sun, X.W. Sun, X.Y. Qiu, L.P. Chen and Y.F. Huang
Immune-related miRNAs in breast milk are extracellular miRNAs that are related to immune organ development and regulation of the immune function in infants and young animals. The goal of this study was to compare the expression levels of five immune-related miRNAs in breast milk in black goats, humans, and dairy cattle. The miRNAs from milk were extracted.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.25.4
- DOI:
- http://dx.doi.org/10.4238/2015.September.25.4
MicroRNAs as novel biomarkers for the differentiation of malignant versus benign thyroid lesions: a meta-analysis
Authors: G.J. Zhou, M. Xiao, L.N. Zhao, J.G. Tang and L. Zhang
The aim of this meta-analysis was to systematically evaluate the diagnostic accuracy of microRNAs (miRNAs) in distinguishing malignant thyroid lesions from benign ones and to determine the potential of miRNAs as diagnostic biomarkers for thyroid cancer. The random-effect model was used to summarize the pooled estimates of diagnostic accuracy, including se.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.3
- DOI:
- 10.4238/2015.July.3.3