Mitochondria
Phylogenetic relationships of twenty Gymnothorax species based on cytochrome b sequence data
Authors: M. Du, S.W. Yin and B.Z. Niu
To study the phylogenetic relationships of the genus Gymnothorax (moray eels) distributed in South China Sea, polymerase chain reactions were performed, and the amplification products were sequenced by cloning into the PMD18T-vector (TaKaRa). The entire gene sequences encoding cytochrome b (1140 bp) for 16 Gymnothorax (G. flav.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028157
- DOI:
- 10.4238/gmr.15028157
Genetic divergence between Mexican Opuntia accessions inferred by polymerase chain reaction-restriction fragment length polymorphism analysis
Authors: S. Samah, E. Valadez-Moctezuma, K.S. Pel�¡ez-Luna, S. Morales-Manzano, P. Meza-Carrera and R.C. Cid-Contreras
Molecular methods are powerful tools in characterizing and determining relationships between plants. The aim of this study was to study genetic divergence between 103 accessions of Mexican Opuntia. To accomplish this, polymerase chain reaction (PCR)-restriction fragment length polymorphism analysis of three chloroplast interge.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027786
- DOI:
- 10.4238/gmr.15027786
Population genetic structure of critically endangered salamander (Hynobius amjiensis) in China: recommendations for conservation
Authors: J. Yang, C.S. Chen, S.H. Chen, P. Ding, Z.Y. Fan, Y.W. Lu, L.P. Yu and H.D. Lin
Amji’s salamander (Hynobius amjiensis) is a critically endangered species (IUCN Red List), which is endemic to mainland China. In the present study, five haplotypes were genotyped for the mtDNA cyt b gene in 45 specimens from three populations. Relatively low levels of haplotype diversity (h = 0.524) and nucleotide diver.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027733
- DOI:
- 10.4238/gmr.15027733
Hypoxia-induced apoptosis and mitochondrial dysfunction in chondrocytes arising from CREB phosphorylation reduction
Authors: Y.Y. Qiu, Y. Chen, T.H. Zeng, W.H. Guo, W.Y. Zhou and X.J. Yang
Chondrocytes, which are embedded within the growth-plate or the intervertebral disc, are sensitive to environmental stresses, such as inflammation and hypoxia. However, little is known about the molecular signaling pathways underlying hypoxia-induced mitochondrial dysfunction and apoptosis in chondrocytes. We first examined th.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027755
- DOI:
- 10.4238/gmr.15027755
Mitochondrial tRNALeu(CUN) A12307G variant may not be associated pancreatic cancer
Authors: Y. Li, A.W. Huang, Y.Z. Chen, W.J. Yang, M.T. Zhou and H.W. Sun
Mitochondrial DNA mutations that lead to mitochondrial dysfunction have long been proposed to play important roles in the development of pancreatic cancer. Of these, alterations to mitochondrial tRNA genes constitute the largest group. Most recently, a variation at position 12307 in the gene encoding tRNALeu(CUN) has been repo.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027906
- DOI:
- 10.4238/gmr.15027906
DNA and RNA polymerase activity in a Moniliophthora perniciosa mitochondrial plasmid and self-defense against oxidative stress
Authors: B.S. Andrade, C. Villela-Dias, D.S. Gomes, F. Micheli and A. G�³es-Neto
Moniliophthora perniciosa (Stahel) Aime and Phillips-Mora is a hemibiotrophic basidiomycete (Agaricales, Tricholomataceae) that causes witches’ broom disease in cocoa (Theobroma cacao L.). This pathogen carries a stable integrated invertron-type linear plasmid in its mitochondrial genome that encodes viral-like DNA and RNA polymerases related to fun.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.June.13.3
- DOI:
- 10.4238/2013.June.13.3
Mitochondrial transfer RNA mutations and hypertension
Authors: S.L. Yin, C. Lan, H. Pei, and Z.Q. Zhu
Mutations in mitochondrial DNA have been found to be associated with hypertension. Of these, mitochondrial transfer RNA (mt-tRNA) is a hot spot for these pathogenic mutations. It is generally believed that these mutations may result in the failure of mt-tRNA metabolism, thereby worsening mitochondrial dysfunction and resulting in hypertension. mt-tRNA is .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.21.42
- DOI:
- 10.4238/2015.December.21.42
Borax-induced apoptosis in HepG2 cells involves p53, Bcl-2, and Bax
Authors: Y. Wei1, F.J. Yuan, W.B. Zhou, L. Wu, L. Chen, J.J. Wang and Y.S. Zhang
Borax, a boron compound and a salt of boric acid, is known to inhibit the growth of tumor cells. HepG2 cells have been shown to be clearly susceptible to the anti-proliferative effects of borax. However, the specific mechanisms regulating this effect are poorly understood. This study aimed to investigate the pathways underlyin.. Read More»
- Genet. Mol. Res. 15(2):
Complete mitochondrial genome of the Southern catfish (Silurus meridionalis Chen) and Chinese catfish (S. asotus Linnaeus): Structure, phylogeny, and intraspecific variation
Authors: Q.R. Wang, C. Xu, C.R. Xu and R.J. Wang
The complete mitochondrial genome of the Southern catfish (Silurus meridionalis) and the Chinese catfish (S. asotus), was determined using the long and accurate polymerase chain reaction (LA-PCR) method. The mitochondrial DNA nucleotide sequences of S. meridionalis and S. asotus were compared with those of 47 other catfish species in the same order. The t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.7
- DOI:
- 10.4238/2015.December.23.7
Respiratory chain complex III deficiency in patients with tRNA-leu mutation
Authors: J. Jiang, X.L. Wang and Y.Y. Ma
The aim of this study was to investigate the clinical and genetic profiles of mitochondrial disease resulting from deficiencies in the respiratory chain complex III. Three patients, aged between 8 months and 12 years, were recruited for this study. The activities of mitochondrial respiratory chain complexes in the peripheral leucocytes were spectrophotome.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.12
- DOI:
- 10.4238/2015.December.28.12