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Mitochondria

Human Genetics   Research Article

Mitochondrial DNA insertions in the nuclear Capra hircus genome

Authors: F.Y. Ning, J. Fu and Z.H. Du

Nuclear mitochondrial pseudogenes (numts), originating from mtDNA insertions into the nuclear genome, have been detected in many species. However, the distribution of numts in the newly published nuclear genome of domestic goat (Capra hircus) has not yet been explored. We used the entire goat mtDNA sequence and nuclear genome,.. Read More»

Genet. Mol. Res. 16(1):
gmr16018266
DOI:
10.4238/gmr16018266
Animal Genetics   Research Article

Analysis of the mitochondrial COI gene and its informative potential for evolutionary inferences in the families Coreidae and Pentatomidae (Heteroptera)

Authors: H.V. Souza1, S.R.C. Marchesin2 and M.M. Itoyama1

The mitochondrial cytochrome oxidase subunit 1 (COI) gene is one of the most popular markers used for molecular systematics. Fragments of this gene are often used to infer phylogenies, particularly the region near the 5'-end, which is used by the DNA Barcoding Consortium. With a growing number of sequences being deposited in the DNA barcoding database, th.. Read More»

Genet. Mol. Res. 15(1):
0.4238/gmr.15017428
DOI:
0.4238/gmr.15017428
Microbial Genetics   Research Article

Synonymous codon usage patterns in different parasitic platyhelminth mitochondrial genomes

Authors: L. Chen D.Y. Yang T.F. Liu X. Nong X. Huang Y. Xie Y. Fu W.P. Zheng R.H. Zhang X.H. Wu X.B. Gu S.X. Wang X.R. Peng G.Y. Yang

We analyzed synonymous codon usage patterns of the mitochondrial genomes of 43 parasitic platyhelminth species. The relative synonymous codon usage, the effective number of codons (NC) and the frequency of G+C at the third synonymously variable coding position were calculated. Correspondence analysis was used to determine the major variation trends shapin.. Read More»

Genet. Mol. Res. 12(1):
2013.February.27.8
DOI:
10.4238/2013.February.27.8
Animal Genetics   Research Article

Changes of peripheral-type benzodiazepine receptors in the penumbra area after cerebral ischemia-reperfusion injury and effects of astragaloside IV on rats

Authors: Y.L. Cao, C.F. Chen, A.W. Wang, Y.B. Feng, H.X. Cheng,W.W. Zhang4and W. Xin

This study investigated the changes in peripheral benzodiazepine receptors (PBRs) in the penumbra after cerebral ischemia-reperfusion injury, and examined the effects of astragaloside IV (AST) on PBRs in rats. Sixty Sprague-Dawley rats were divided into a sham operation group, a model group, and three AST treatment groups. Cerebral ischemic models were in.. Read More»

Genet. Mol. Res. 14(1):
2015.January.23.1
DOI:
10.4238/2015.January.23.1
Human Genetics   Research Article

Comparison of DNA extraction methods for polymerase chain reaction amplification of guanaco (Lama guanicoe) fecal DNA samples

Authors: M.I. Espinosa, A. Bertin, F.A. Squeo, A. Cort�©s and N. Gouin

Feces-based population genetic studies have become increasingly popular. However, polymerase chain reaction (PCR) amplification rates from fecal material vary depending on the species, populations, loci, and extraction protocols. Here, we assessed the PCR amplification success of three microsatellite markers and a segment of the mitochondrial control regi.. Read More»

Genet. Mol. Res. 14(1):
2015.January.23.13
DOI:
10.4238/2015.January.23.13
Animal Genetics   Research Article

Unraveling the variability and genetic structure of barker frog Physalaemus cuvieri (Leiuperinae) populations from different regions of Brazil

Authors: M. Conte, C.P. Targueta, M.I. Zucchi, A.P. Souza and S.M. Recco-Pimentel

The barker frog Physalaemus cuvieri is widely distributed in South America and is found in all regions of Brazil. Significant intraspecific morphological variation in this species has been reported. To determine the genetic structure of the natural Brazilian populations of P. cuvieri, 10 different populations geographically se.. Read More»

Genet. Mol. Res. 13(3):
2014.February.21.4
DOI:
10.4238/2014.February.21.4
Animal Genetics   Research Article

Phylogenetic analysis of the Mongolian gerbil (Meriones unguiculatus) from China based on mitochondrial genome

Authors: C.L. Li, X.Y. Du, J. Gao, C. Wang, H.G. Guo, F.W. Dai, X.Y. Sa, W. An and Z.W. Chen

Meriones unguiculatus (Gerbillinae, Rodentia) is widely used as an animal model of human disease. Here, we provide the first report of the complete mitochondrial genome sequence of M. unguiculatus (GenBank accession Nos. KF425526 and NC_023263). The sequence contained the conserved vertebrate pattern of 13 protein-coding genes, 2 ribosomal RNAs, 22 transf.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037703
DOI:
10.4238/gmr.15037703
Human Genetics   Research Article

Mitochondrial gene expression in the liver and muscle of high and low feed efficiency Japanese quail layers subjected to different environmental temperatures

Authors: D.M. Voltolini, A.P. Del Vesco, E. Gasparino, S.E.F. Guimar�£es, A.R. Oliveira Neto, E. Batista and A.P.S. Ton

We evaluated the adenine nucleotide translocator (ANT) and cytochrome oxidase subunit III (COX III) mRNA expressions in the muscle and liver of Japanese quails presenting high and low feed efficiency (FE), and subjected them to three different environmental temperatures: comfort, heat stress (38°C), and cold stress (10°.. Read More»

Genet. Mol. Res. 13(3):
2014.July.4.8
DOI:
10.4238/2014.July.4.8
Human Genetics   Research Article

Increased ROS generation and SOD activity in heteroplasmic tissues of transmitochondrial mice with A3243G mitochondrial DNA mutation

Authors: J. Li1, K. Zhou2, X. Meng1, Q. Wu1, S. Li1, Y. Liu2 and J. Wang1

The mitochondrial A3243G tRNALeu(UUR) mutation associated with a variety of mitochondrial disorders results in a severe respiratory deficiency, an increase in reactive oxygen species (ROS) production and activities of anti-oxidative enzyme in vitro. However, the phenotypic implications of this mutation have not been described in vivo. Here, mitochondria c.. Read More»

Genet. Mol. Res. 7(4):
vol7-4gmr480
DOI:
10.4238/vol7-4gmr480
Human Genetics   Research Article

Zhi-Long-Huo-Xue-Tong-Yu modulates mitochondrial fission through the ROCK1 pathway in mitochondrial dysfunction caused by streptozotocin-induced diabetic kidney injury

Authors: W.H. Wu, M.P. Zhang, S.J. Yang, Q. Liu, X. Bai, J.H. Qin,B. Peng, S.T. Ou, J. Liu, C.Y. Zhao, Q. Zhang, Q.D. Hu and L. Xue

Zhi-Long-Huo-Xue-Tong-Yu (ZLHXTY) is a defined mixture of 5 herbs developed by Professor S.J. Yang according to the Buyang Huanwu decoction method, which has been recorded in the Yilingaicuo. This study investigated the renoprotective effects of ZLHXTY on mitochondrial dysfunction induced by diabetic kidney injury in a diabetic rat model. Diabetes was ind.. Read More»

Genet. Mol. Res. 14(2):
2015.May.4.18
DOI:
10.4238/2015.May.4.18