Mrna
A brief study on Operon model
Authors: Steve Johnson
Operon, hereditary administrative framework found in microbes and their infections in which qualities coding for practically related proteins are bunched along the DNA... Read More»
- Genet. Mol. Res. 20(3):
ERCC1 mRNA expression is associated with the clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy
Authors: H. Zhang1, J. Li2, Y. Zhang2, M. Sun3, P. Zhao1, G. Zhang2, C. Jin2, L. Sun1, M. He1, B. Wang2 and X. Zhang2
We conducted a prospective study to analyze the expression of the excision repair cross-complementing group 1 (ERCC1) and ribonucleotide reductase subunit M1 (RRM1) genes in 297 Chinese patients with advanced non-small cell lung cancer (NSCLC). The goal of this study was to evaluate these genes as potential biomarkers for prediction of tumor response and .. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.4.16
- DOI:
- 10.4238/2014.December.4.16
ERCC1 mRNA expression is associated with the clinical outcome of non-small cell lung cancer treated with platinum-based chemotherapy
Authors: H. Zhang1, J. Li2, Y. Zhang2, M. Sun3, P. Zhao1, G. Zhang2, C. Jin2, L. Sun1, M. He1, B. Wang2 and X. Zhang2
We conducted a prospective study to analyze the expression of the excision repair cross-complementing group 1 (ERCC1) and ribonucleotide reductase subunit M1 (RRM1) genes in 297 Chinese patients with advanced non-small cell lung cancer (NSCLC). The goal of this study was to evaluate these genes as potential biomarkers for prediction of tumor response and .. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.4.16
- DOI:
- 10.4238/2014.December.4.16
Expression profile analysis reveals putative prostate cancer-related microRNAs
Authors: H. Song1*, Y. Liu2*, J. Pan3 and S.T. Zhao1
Annotation of prostate cancer (PC) genomes provides a foundation for discoveries that can improve the understanding and treatment of the disease. Therefore, in the present study, we used the Student t-test to identify differentially expressed PC-related mRNAs and microRNAs (miRNAs). Then, we performed interrelated mapping of miRNA target genes between abn.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.4
- DOI:
- 10.4238/2013.October.24.4
Detection of CK19, LUNX, and KS1/4 mRNA expression in the peripheral blood for diagnosis of micrometastases in patients with non-small cell lung cancer and their clinical implications
Authors: L. Yan, Y. Yao, L.H. Wang, M.L. Wang and X.H. Fu
The expression of CK19, LUNX, and KS1/4 mRNA biomarkers was detected in the peripheral blood of non-small cell lung cancer (NSCLC) patients to investigate the feasibility of indicating lung cancer micrometastases. Micrometastases were identified in the peripheral blood of 32 NSCLC patients, 15 benign pulmonar.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.17
- DOI:
- 10.4238/2015.November.24.17
Effects of lipopolysaccharide on the stearoyl-coenzyme A desaturase mRNA level in bovine primary hepatic cells
Authors: Q.D. Jiang, H.P. Li, F.J. Liu, X.J. Wang, Y.J. Guo, L.F. Wang, W.F. Lu, H.J. Li, X.P. Li and Y.Y. Wang
This study aimed to compare the effects of lipopolysaccharide (LPS) on stearoyl-coenzyme A desaturase (SCD) gene expression in mouse primary hepatic cells. To obtain sufficient total RNA, primary hepatic cells were plated on 6-cm diameter-type collagen 1-coated dishes (1 x 106 cells per dish). The test was divided into 6 group.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.12
- DOI:
- 10.4238/2014.January.24.12
Eosinophil cationic protein mRNA expression in children with bronchial asthma
Authors: H.Y. Yu1, X.Y. Li2, Z.F. Cai1, L. Li3, X.Z. Shi4, H.X. Song5 and X.J. Liu1
Studies have shown that eosinophils are closely related to pathogenesis of bronchial asthma. Eosinophils release eosinophil cationic protein (ECP), which plays an important role in infection and allergic reactions. Serum ECP mRNA expression in children with bronchial asthma has not been adequately investigated. We analyzed serum ECP mRNA expression in 63 .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.13.11
- DOI:
- 10.4238/2015.November.13.11
Molecular characterization, expression, polymorphism of NR5A2 and its relationship with litter size in Hu sheep
Authors: Y.X. Li, J. Zhang, Y. Qian, C.H. Meng, H.L. Wang, X.J. Tao, S. Zhong, S.X. Cao and Q.F. Li
NR5A2 has been implicated in processes as diverse as steroidogenesis, cellular proliferation, ovarian follicular development, ovulation, and fertility in mammals. However, data about the relationship between NR5A2 and prolificacy in mammals are lacking. In the present study, we identified and characterized NR5A2 of Hu sheep, a.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.20
- DOI:
- 10.4238/2015.October.19.20
PPAR�± signal pathway gene expression is associated with fatty acid content in yak and cattle longissimus dorsi muscle
Authors: W. Qin, C.N. Liang, X. Guo, M. Chu, J. Pei, P.J. Bao, X.Y. Wu, T.K. Li and P. Yan
ntramuscular fatty acid (FA) is related to meat qualities such as juiciness, tenderness, palatability, and shear force. PPARα plays an important role in lipid metabolism in the liver and skeletal muscle. This study investigated FA composition in yaks and cattle, in order to ascertain whether a correlation between PPARα signal pathway genes as .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.9
- DOI:
- 10.4238/2015.November.18.9
Expression patterns of Doppel in differential ovine PRNP genotypes: quantification using real-time RT-PCR
Authors: C. Wang, C.-L. Zhao, L. Liu, R. Wu and X.-L. Zhang
Doppel is a homologue of cellular prion protein (PrP)-like protein (PrPC). Different tissue samples were collected from the central nervous system plus four regions of lymphoid system, eleven regions of digestive tract and two reproductive organs from four ARR/ARQ and four ARH/ARQ sheep, genotypes of the PrP gene. Total RNA wa.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.3
- DOI:
- 10.4238/2015.October.9.3