Mrna
Expression patterns of two heat-shock cognate 70 genes during immune responses and larval development of the Chinese mitten crab Eriocheir sinensis
Authors: P. Li, X.F. Jiang, W.B. Guo, J. Yan and K.Y. Zhou
Two heat-shock protein (HSP) 70 family transcripts, heat-shock protein 70 cognate 5 and heat-shock protein 70 cognate 3 (designated as EsHSC70-5 and EsHSC70-3, respectively), were isolated from the Chinese mitten crab Eriocheir sinensis and their expression profiles were evaluated for their responsiveness to larval development and immune challenge in adul.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15036319
- DOI:
- 10.4238/gmr.15036319
Lipopolysaccharide and �²-1,3-glucan binding protein in the hard clam (Meretrix meretrix): Molecular characterization and expression analysis
Authors: S.X. Liu, Z.H. Qi, J.J. Zhang, C.B. He, X.G. Gao and H.J. Li
Pattern recognition molecules play an important role in innate immunity by recognizing conserved molecular patterns that are present on the surface of invading microorganisms. In this study, a lipopolysaccharide and β-1,3-glucan binding protein (LGBP) gene was cloned from the hard clam Meretrix meretrix .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.10
- DOI:
- 10.4238/2014.July.4.10
CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue
Authors: J.B. Qian, H.B. Liu, Y. Zhu, F. Lu, Q.C. Yang and Y. Shen
The mRNA expression of cell adhesion molecule 1 (CADM1) and its clinicopathological significance in esophageal squamous cell carcinoma (ESCC) tissues were investigated. CADM1 mRNA and protein expression were detected in tissue samples from 50 patients with ESCC by reverse transcription-polymerase chain reaction (RT-PCR) and st.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029178
- DOI:
- 10.4238/gmr16029178
Predicted philogeny, secondary conformational structure, and epitope antigenicity of immunological sequences in poultry
Authors: L.J. Lara, A.P. Peconick, ��.J. Fassani, A.M.P. J�ºnior, P.R.B. Chalfun, D.L. Raymundo, T.A. Bar�§ante and J.M. de P. Bar�§ante
Poultry production is faced with different types of stresses that are responsible for issues of animal welfare as well as for economic losses. Moreover, the immunity decreases when animals are stressed. In silico analyses are important in reducing the cost and in increasing the accuracy of scientific results. A bioinformatics .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029423
- DOI:
- 10.4238/gmr16029423
Responsivity to PGE2 labor induction involves concomitant differential prostaglandin E receptor gene expression in cervix and myometrium
Authors: C.K. Konopka, W.G. Glanzner, M.L. Rigo, M.T. Rovani, F.V. Comim, P.B.D. Gon�§alves, E.N. Morais, A.Q. Antoniazzi, C.F. Mello and I.B.M. Cruz
Prostaglandin E2 (dinoprostone) is largely used for labor induction. However, one-third of patients do not respond to treatment. One cause of this poor response may be associated with changes in regulation of prostaglandin E receptors (EP1-4). In this study, we investigated EP mRNA expression in the uterine cervix and lower uterine segment myometrium for .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.25
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.25
Molecular cloning, tissue expression pattern, and copy number variation of porcine SCUBE3
Authors: X. Liu*, L.G. Wang*, L.C. Zhang, H. Yan, K.B. Zhao, J. Liang, N. Li, L. Pu,T. Zhang and L.X. Wang
The signal peptide CUB EGF-like domain-containing protein 3 (SCUBE3) gene is a member of SCUBE gene family and plays important roles in bone cell biology and the determination of limb bone length. In this study, the full-length transcript of porcine SCUBE3 was cloned using reverse transcription-polymerase chain reaction and rapid amplification of cDNA end.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017010
- DOI:
- 10.4238/gmr.15017010
Tissue-specific adaptive levels of glucocorticoid receptor alpha mRNA and their relationship with insulin resistance
Authors: R.B. Castro C.A. Longui C.D.C. Faria T.S. Silva F. Richeti M.N. Rocha M.R. Melo W.L. Pereira E.G. Chamlian L.A. Rivetti
Insulin resistance is an underlying cause of metabolic changes associated with cardiovascular diseases. Glucocorticoids are known determinant factors of insulin resistance. We quantified glucocorticoid receptor alpha (GRÃ?±) mRNA and 11 beta-hydroxysteroid dehydrogenase type 1 (11Ã?²-HSD1) mRNA in various tissues of 35 patients with previously established .. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.21.1
- DOI:
- 10.4238/2012.November.21.1
Identification of transgenic cloned dairy goats harboring human lactoferrin and methylation status of the imprinted gene IGF2R in their lungs
Authors: Y.L. Zhang, G.M. Zhang, Y.J. Wan, R.X. Jia, P.Z. Li, L. Han, F. Wang and M.R. Huang
Dairy goat is a good model for production of transgenic proteins in milk using somatic cell nuclear transfer (SCNT). However, animals produced from SCNT are often associated with lung deficiencies. We recently produced six transgenic cloned dairy goats harboring the human lactoferrin gene, including three live transgenic clones and three deceased transgen.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.22.3
- DOI:
- http://dx.doi.org/10.4238/2015.September.22.3
Effect of heat stress on heat-shock protein (Hsp60) mRNA expression in rainbow trout Oncorhynchus mykiss
Authors: H.N. Shi, Z. Liu, J.P. Zhang, Y.J. Kang, J.F. Wang, J.Q. Huang and W.M. Wang
The enhanced expression of heat shock proteins (hsps) in organisms can be detected in response to many kinds of stressor. For fish, high temperature is an important stressor, and hsp expression is associated with differences in environmental temperature. In this study, rainbow trout (Oncorhynchus mykiss) that were accustomed to an aquatic temperature of 1.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.20
- DOI:
- 10.4238/2015.May.18.20
Up-regulation of Id1 in peripheral blood of psoriatic patients
Authors: C. Ronpirin, M. Achariyakul, T. Tencomnao, J. Wongpiyabovorn and W. Chaicumpa
Although the precise causes of psoriasis are unclear, it is widely accepted that psoriasis is a disorder in which factors in the immune system, enzymes, and other biochemical substances that regulate skin cell division are impaired, leading to rapid proliferation of keratinocytes and incomplete keratinization. Expression of th.. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr963
- DOI:
- 10.4238/vol9-4gmr963