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Mrna

Medical Genetics   Research Article

Genomic structure, polymorphism and expression analysis of growth hormone-releasing hormone and pituitary adenylate cyclase activating polypeptide genes in the half-smooth tongue sole (Cynoglossus semilaevis)

Authors: Q. Ma, S.F. Liu, Z.M. Zhuang, L. Lin, Z.Z. Sun, C.L. Liu, Y.Q. Su and Q.S. Tang

Growth hormone-releasing hormone (GHRH) and pituitary adenylate cyclase activating polypeptide (PACAP) regulate development and somatic growth in teleosts; they may be associated with sexual growth dimorphism in the half-smooth tongue sole (Cynoglossus semilaevis). We found that the full-length GHRH and PACAP gene sequences ob.. Read More»

Genet. Mol. Res. 10(4):
2011.December.12.1
DOI:
10.4238/2011.December.12.1
Medical Genetics   Research Article

Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis.

Authors: C. Wang, D.Z. Hu and J.Z. Liu

To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.19
DOI:
10.4238/2015.May.22.19
Medical Genetics   Research Article

Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis

Authors: C. Wang D.Z. Hu and J.Z. Liu

To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»

Genet. Mol. Res. 14(2):
2015.May.22.19
DOI:
10.4238/2015.May.22.19
Medical Genetics   Research Article

Porcine MAP3K5 analysis: molecular cloning, characterization, tissue expression pattern, and copy number variations associated with residual feed intake

Authors: L. Pu, L.C. Zhang, J.S. Zhang, X. Song, L.G. Wang, J. Liang, Y.B. Zhang, X. Liu, H. Yan, T. Zhang, J.W. Yue, N. Li, Q.Q. Wu and L.X. Wang

Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is essential for apoptosis, proliferation, differentiation, and immune responses, and is a candidate marker for residual feed intake (RFI) in pig. We cloned the full-length cDNA sequence of porcine MAP3K5 by rapid-amplification of cDNA ends. The 5451-bp gene contains a 5'-untranslated region (UTR) .. Read More»

Genet. Mol. Res. 15(3):
gmr.15037998
DOI:
10.4238/gmr.15037998
Animal Genetics   Research Article

14-3-3 Gene expression in regenerating rat liver after 2/3 partial hepatectomy

Authors: D.M. Xue, X.Q. Guo, R. Chen, Z.P. Niu and C.S. Xu

14-3-3 Proteins are a ubiquitous family of molecules that participate in protein kinase signaling pathways in all eukaryotic cells. Functioning as phosphoserine/phosphothreonine-binding modules, 14-3-3 proteins participate in the phosphorylation-dependent protein-protein interactions that control progression through the cell cycle, initiation and.. Read More»

Genet. Mol. Res. 14(1):
2015.March.20.12
DOI:
10.4238/2015.March.20.12
Animal Genetics   Research Article

Differential gene expression of epigenetic modifying enzymes between Tibet pig and Yorkshire in high and low altitudes

Authors: D.M. Ban, B. Zhang, Z.X. Wang, H. Zhang and C.X. Wu

Epigenetic modifying enzymes play important roles in the adaptation to hypoxia, although no studies have examined their expression levels in Tibet pigs. The lung is an important functional organ in hypoxia adaptation. In this study, we examined the mRNA expression level of 5 enzymes in the lung of Tibet pigs using real-time polymerase chain reaction to de.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.13.6
DOI:
http://dx.doi.org/10.4238/2015.April.13.6
Human Genetics   Research Article

A C-type lectin fold gene from Japanese scallop Mizuhopecten yessoensis, involved with immunity and metamorphosis

Authors: X.B. Bao, C.B. He, C.D. Fu, B. Wang, X.M. Zhao, X.G. Gao andW.D. Liu

C-type lectins are a superfamily of Ca2+-dependent carbohydrate-recognition proteins that are well known for their participation in pathogen recognition and clearance. In this study, a putative C-type lectin fold (MyCLF) gene was identified from the Japanese scallop Mizuhopecten yessoensis. The full-length of MyCLF was 645 bp, encoding a polypeptide of 16.. Read More»

Genet. Mol. Res. 14(1):
2015.March.27.11
DOI:
10.4238/2015.March.27.11
Microbial Genetics   Research Article

Molecular cloning, characterization, and expression of vacuolar-type-H+-ATPase B1 (VHAB1) gene in the gill of Anguilla marmorata

Authors: L. Li, Y.H. Jia, P. Li, S.W. Yin, G.S. Zhang, X.L. Wang, Y.Y. Wang and X.J. Wang

We explored the molecular mechanism of the regulation of vacuolar-type-H+-ATPase B1 (VHAB1) in elvers in the response to salinity. The full-length cDNA of VHAB1 in Anguilla marmorata (designated as AmVHAB1), which was 1741 base pairs (bp) in length, was found to encompass a 1512-bp open reading frame encoding a polypeptide with 503 amino acids (55.9 kDa),.. Read More»

Genet. Mol. Res. 14(3):
2015.July.17.9
DOI:
10.4238/2015.July.17.9
Animal Genetics   Research Article

Molecular cloning and expression analysis of a matrix Gla protein gene in the spinyhead croaker, Collichthys lucidus

Authors: W. Song, M.D. Zhao, K.J. Jiang, F.Y. Zhang, M. Zhao, Y.Y. Meng and L.B. Ma

The matrix Gla (gamma-carboxyglutamic acid-rich) protein (MGP), a vitamin K-dependent and Gla-containing protein, is a calcification inhibitor that mainly functions in tissue calcification and mineralization. In this study, we obtained the complete cDNA sequence of MGP from the spinyhead croaker (Collichthys lucidus), which we.. Read More»

Genet. Mol. Res. 15(4):
gmr15049028
DOI:
10.4238/gmr15049028
Animal Genetics   Research Article

Molecular cloning and sequence analysis of follicle-stimulating hormone beta polypeptide precursor cDNA from the bovine pituitary gland

Authors: L.S. Dai, Y.M. Zhao, G.L. Zhang, R.F. Zhao, H. Jiang, T.H. Ma, Y. Gao, B. Yuan, Y.L. Xu, W.Y. Yu, Z.H. Zhao and J.B. Zhang

Follicle-stimulating hormone (FSH) plays an essential role in mammalian spermatogenesis and follicular development. In a previous study, we demonstrated that some bulls carry numerous linked mutations in the FSH beta-subunit (FSHB) gene, and that these bulls have poor-quality semen, low fertility, and slightly lower serum FSH .. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr997
DOI:
10.4238/vol10-3gmr997