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Mrna

Animal Genetics   Research Article

Molecular cloning and characterization of a novel Y-box gene from Sepiella maindroni

Authors: H.P. Si, C.L.Wang, Y.Y. Zhang, C.K. Mu, P.P. Zhan, R.H. Li and W.W. Song

Y-box proteins are a family of highly conserved nucleic acid binding proteins that interact with genome and transcription product to modulate the transcriptional and translational processes. In the present study, a complete mRNA of Y-box binding protein (designated SmYB) was obtained from Sepiella maindroni by amplification of flanking sequences. The full.. Read More»

Genet. Mol. Res. 14(2):
2015.May.29.7
DOI:
10.4238/2015.May.29.7
Microbial Genetics   Research Article

mRNA expression of prolactin receptor in sheep pituitary and its effect on maternal behavior

Authors: L.P. Wang

Prolactin receptor (PRLR) is the specific receptor for prolactin. Brain-specific control of PRLR gene expression is correlated with the induction of maternal behavior. The aim of this study was to investigate the dynamic changes in the PRLR mRNA level in the sheep pituitary gland and its effect on ewe maternal behavior. The mRNA expression of PRLR during .. Read More»

Genet. Mol. Res. 14(3):
2015.July.31.13
DOI:
10.4238/2015.July.31.13
Human Genetics   Research Article

Drosha, DGCR8, and Dicer mRNAs are down-regulated in human cells infected with dengue virus 4, and play a role in viral pathogenesis

Authors: S.M.M. Casseb, D.B. Simith, K.F.L. Melo, M.H. Mendon�§a, A.C.M. Santos, V.L. Carvalho, A.C.R. Cruz and P.F.C. Vasconcelos

Dengue virus (DENV) and its four serotypes (DENV1-4) belong to the Flavivirus genus of the Flaviviridae family. DENV infection is a life-threatening disease, which results in up to 20,000 deaths each year. Viruses have been shown to encode trans-regulatory small RNAs, or microRNAs (miRNAs), which bind to messenger RNA and nega.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027891
DOI:
10.4238/gmr.15027891
Human Genetics   Research Article

HPV infection-associated anogenital cyto-colpo-histological findings and molecular typing in HIV-positive women

Authors: F.K. Tso, C.L.L. Rodrigues, J.E. Levi, M.G. Mattosinho de Castro Ferraz, N.M.G. Speck and J.C.L. Ribalta

HIV and human papillomavirus (HPV) coinfection is increasing, especially in the anal canal (AC) and cervico-vaginal regions.We identified anal epithelium abnormalities related to high-risk HPV (HR-HPV) lesions in the lower genital tracts (LGTs) of HIV-positive women, described the HPV genotypes identified, and assessed the expression of E6/E7 oncogenes in.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.36
DOI:
10.4238/2015.December.21.36
Human Genetics   Research Article

Expression of human papillomavirus E6 and E7 oncoprotein mRNA in women with low-grade squamous intraepithelial lesions or less

Authors: D.C. Casagrande, J.C.L. Ribalta, K.D.P.F. Leite, M. Schimidt and N.M.D.G. Speck

We verified the prevalence of human papillomavirus (HPV) E6/E7 protein mRNA expression in patients with low-grade squamous intraepithelial lesions (LSILs) and negative cervicovaginal cytology. To investigate the relationship between mRNA expression and viral infection type, we assessed genotyping in single infections. Samples from 825 women were submitted.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017916
DOI:
10.4238/gmr.15017916
Animal Genetics   Research Article

Genetic effect of an A/G polymorphism in the HSP70 gene on thermotolerance in chicken

Authors: Z.Y. Chen, W.W. Zhang, J.K. Gan, L.N. Kong, X.Q. Zhang,D.X. Zhang and Q.B. Luo

Studying thermotolerance is important for the prevention of thermostress in chickens. This study aimed to analyze the effect of mutations in the heat shock protein 70 (HSP70) gene on chicken thermotolerance. The C.-69A>G SNP in the 5'-flanking region of the HSP70 gene was genotyped in Lingshan and White Recessive Rock (WRR).. Read More»

Genet. Mol. Res. 15(2):
gmr.15028271
DOI:
10.4238/gmr.15028271