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Gene silencing during development ofin vitro-produced female bovine embryos
Authors: G.K.F. Merighe, F.H. Biase, W.K.F. Santos-Biase, M.S. Miranda,T.H.C. de Bem, Y.F. Watanabe and F.V. Meirelles
In early development, female embryos (XX) produce twice the transcripts of X-linked genes compared with male embryos (XY). During the course of development, inactivation of the X chromosome equilibrates gene dosage, making the development of female embryos viable. Moreover, the biotechnologies used for producing embr.. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr638
- DOI:
- 10.4238/vol8-3gmr638
Chloroplast diversity of Casearia grandiflora in the Cerrado of Piau� State
Authors: M.F. Costa, A.A. Pereira, J.B. Pinheiro, M.I. Zucchi, A.S.F. Ara�ºjo, R.L.F. Gomes, S.E.S. Valente, M.E.A. Oliveira and A.C.A. Lopes
Casearia grandiflora (Salicaceae) is a typical Cerrado species adapted to disturbed environments, making it useful for restoration projects. Knowledge of genetic diversity is important for establishing conservation strategies for this species. This study aimed to compare chloroplast haplotype diversity and structure of C. gran.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019572
- DOI:
- 10.4238/gmr16019572
Complete mitochondrial genome of the Amur hedgehog Erinaceus amurensis (Erinaceidae) and higher phylogeny of the family Erinaceidae
Authors: N.H. Kim, S.J. Lim, H.M. Chae and Y.C. Park
We sequenced and characterized the complete mitogenome (KX964606) of the Amur hedgehog Erinaceus amurensis to provide more data for comparative mitogenomics of the genus Erinaceus (Erinaceidae). The mitogenome of E. amurensis is a circular molecule 16,941 bp long, consisting of a control region and a conserved set of 37 genes .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019300
- DOI:
- 10.4238/gmr16019300
Mitochondria-dependent apoptogenic activity of the aqueous root extract of Croton membranaceus against human BPH-1 cells
Authors: D.K. Afriyie, G.A. Asare, K. Bugyei, J. Lin, J. Peng and Z. Hong
The results of previous case-control studies examining the relationship between the interleukin (IL)-6 gene -174G>C polymorphism and lung cancer are controversial. In this study, we evaluated the relationship between the IL-6 gene -174G>C polymorphism and lung cancer. We selected 5 case-control studies related to the IL-6 gene -174G>C polymorphis.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.15.18
- DOI:
- 10.4238/2015.January.15.18
Marsdenia tenacissima extract sensitizes MG63 cells to doxorubicin-induced apoptosis
Authors: T. Huang, W.H. Gong, C.P. Zou, X.C. Li, G.J. Jiang, X.H. Liand H. Qian
Marsdenia tenacissima extract (MTE) is a new plate-derived biotechnology product that is frequently used, but occasionally reported, in the field of chemotherapy. In this study, we assessed the antitumor activity and related mechanisms of MTE by various biotechnological methods. The survival rates of MG63 osteosarcoma cells tr.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.3
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.3
Serum thyroid hormone reference intervals in the apparently healthy individuals of Zhengzhou area of China
Authors: P. Wang, Y.J. Gao, J. Cheng, G.L. Kong, Y. Wang, X.Y. Wu, Z.G. Zhao and H.J. Yuan
This study aimed to establish reference intervals for serum thyroid hormones [serum thyroid-stimulating hormone (TSH), triiodothyronine (TT3), thyroxine (TT4), free triiodothyronine (FT3), and free thyroxine (FT4)] in apparently healthy individuals living in Zhengzhou. According to the requirement for laboratory support for th.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.15
- DOI:
- 10.4238/2014.April.14.15
Molecular cloning and differential expression of the glucocorticoid receptorgene in the estuarine tapertail anchovy Coilia nasus
Authors: F.K. Du, G.C. Xu, Y. Li, Z.J. Nie and P. Xu
To understand the regulation of the glucocorticoid receptor gene (Gcr) during loading and transport stress in fish, the Gcr gene of Coilia nasus was cloned. Gcr in C. nasus is expressed strongly in the liver and muscle, and less stronglyin the gills, brain, spleen, intestine, trunk kidney, and head kidney. Gcr expression in bo.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029125
- DOI:
- 10.4238/gmr16029125
Computational prediction and experimental validation of a novel miRNA in Suaeda maritima, a halophyte
Authors: S.A. Gharat and B.P. Shaw
The lack of available transcriptome data for plants of no economic or agronomic importance limits the identification of miRNAs in many species. Considering the possible similarity of the transcriptome between related species, the present study used expressed sequence tags (ESTs) of Suaeda salsa and Suaeda glauca to identify conserved miRNAs, which were va.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017527
- DOI:
- 10.4238/gmr.15017527
Isolation and characterization of a novel acidic matrix protein hic22 from the nacreous layer of the freshwater mussel, Hyriopsis cumingii
Authors: X.J. Liu, C. Jin, L.M. Wu, S.J. Dong, S.M. Zeng and J.L. Li
Matrix proteins that either weakly acidic or unusually highly acidic have important roles in shell biomineralization. In this study, we have identified and characterized hic22, a weakly acidic matrix protein, from the nacreous layer of Hyriopsis cumingii. Total protein was extracted from the nacre using 5 M EDTA and hic22 was purified using a DEAE-sepharo.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038656
- DOI:
- 10.4238/gmr.15038656
Variation and genetic structure of Tunisian Festuca arundinacea populations based on inter-simple sequence repeat pattern
Authors: N. Chtourou-Ghorbel, H. Elazreg, S. Ghariani, N. Ben Mheni, M. Sekmani, M. Chakroun and N. Trifi-Farah
Tunisian tall fescue (Festuca arundinacea Schreb.) is an important grass for forages or soil conservation, particularly in marginal sites. Inter-simple sequence repeats were used to estimate genetic diversity within and among 8 natural populations and 1 cultivar from Northern Tunisia. A total of 181 polymorphic inter-simple sequence repeat markers were ge.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.17
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.17