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Human Genetics   Research Article

Genetic diversity of the Neotropical tree Hancornia speciosa Gomes in natural populations in Northeastern Brazil

Authors: H.J. Jimenez, L.S.S. Martins, A.V.V. Montarroyos, J.F. Silva Junior, A.L. Alzate-Marin and R.M. Moraes Filho

Mangabeira (Hancornia speciosa Gomes) is a fruit tree of the Apocynaceae family, which is native to Brazil and is a very important food resource for human populations in its areas of occurrence. Mangabeira fruit is collected as an extractive activity, and no domesticated varieties or breeding programs exist. Due to a reduction in the area of ecosystems wh.. Read More»

Genet. Mol. Res. 14(4):
2015.December.21.48
DOI:
10.4238/2015.December.21.48
Animal Genetics   Research Article

Effect of odanacatib on root resorption and alveolar bone metabolism during orthodontic tooth movement

Authors: X.X. Wei, J.P. Chu, Y.Z. Zou, N. Ru, S.X. Cui and Y.X. Bai

The aim of this study was to investigate the effect of local administration of odanacatib (ODN) on orthodontic root resorption and the status of alveolar bone metabolism in rat molars. All specimens were scanned using microcomputed tomography and then the raw images were reconstructed. The total volume of the root resorption craters of the 60 g-NS (normal.. Read More»

Genet. Mol. Res. 14(4):
2015.December.22.23
DOI:
10.4238/2015.December.22.23
Human Genetics   Research Article

Inactivation of putative PKS genes can double geldanamycin yield in Streptomyces hygroscopicus 17997

Authors: Y.H. Li, M. Li, W.Q. He, Y.G. Wang and R.G. Shao

The putative polyketide biosynthesis (PKS) genes cos10 and pg10 were inactivated by insertion of a kanamycin-resistance gene into the genome of the geldanamycin-producing strain, Streptomyces hygroscopicus 17997. The resultant inactivation were confirmed by PCR analysis. The abilities of the PKS gene inactivation strains to produce geldanamycin were compa.. Read More»

Genet. Mol. Res. 12(2):
2013.June.21.3
DOI:
10.4238/2013.June.21.3