Polymorphism
VKORC1 rs2359612 and rs9923231 polymorphisms correlate with high risks of cardiovascular and cerebrovascular diseases
Authors: Y. Li, J. Zhu and J.Q. Ding
We aimed to confirm the correlations between rs2359612 and rs9923231 single nucleotide polymorphisms (SNPs) in the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene and the risk of cardiovascular and cerebrovascular diseases (CCVDs) using meta-analysis. Electronic databases were exhaustively searched for rel.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.38
- DOI:
- 10.4238/2015.November.18.38
Association of neuropeptide Y and gonadotrophin-releasing hormone receptor gene SNPs with breeding value for growth and egg production traits in Mazandaran native chickens
Authors: S.A. Fatemi, H. Mehrabani-Yeganeh, A. Nejati-Javaremi and Sh. Niknafs
Neuropeptide Y (NPY) and gonadotrophin-releasing hormone receptor (GnRHR) are two candidate genes with a wide variety of physiological functions in growth and especially in reproduction processes. We examined the association of one SNP from each of these genes with growth- and egg production-related traits in Mazandaran native chickens. Two hundred and si.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.9
- DOI:
- 10.4238/2012.July.10.9
Nine polymorphic STR loci in the HLA region in the Shaanxi Han population of China
Authors: H.B. Zhang, S.G. Wei, B. Yu, L. Li and J.H. Lai
A large number of microsatellite genetic markers have been identified in the human leukocyte antigen (HLA) region. We investigated genetic polymorphism of the nine short tandem repeat (STR) loci (D6S276, MOGCA, D6S265, MIB, D6S273, G51152, TAP1CA, RING3CA, and D6S291) in the HLA region in the Shaanxi Han population. Using a fluorescence-labeled multiplex-.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.8
- DOI:
- 10.4238/2012.July.10.8
Multidrug resistance gene (MDR1) polymorphisms may not be directly associated with response to imatinib in chronic myeloid leukemia
Authors: J.L. Wang, H.J. Liu, F. Li, W.Y. Yang, J.M. Wang, S.F. Tan and Q. Wang
Our study aimed to investigate the association between multidrug resistance (MDR1) gene polymorphisms and the response to imatinib (IM) in chronic myeloid leukemia (CML). An electronic databases in PubMed, Cochrane Library, Wanfang, China National Knowledge Infrastructure, and VIP were searched using combinations of k.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.4
- DOI:
- 10.4238/2015.November.24.4
Angiotensin II type 1 receptor gene A1166C polymorphism and breast cancer susceptibility
Authors: L. Li, F. Wang, P.W. Lv, M.Z. Zhu, J.J. He, G.C. Guo, Y.T. Gu and M.L. Han
Numerous studies have evaluated the association between the angiotensin II type-1 receptor (AGTR1) gene A1166C polymorphism and breast cancer risk. However, the specific association is controversial. The aim of the present study was to derive a more precise estimation of the relationship. A comprehensive research was conducted.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.9
- DOI:
- 10.4238/2015.November.24.9
RANTES gene polymorphisms (-403G>A and -28C>G) associated with hepatitis B virus infection in a Saudi population
Authors: A. Al-Qahtani, S. Alarifi, M. Al-Okail, Z. Hussain4, A. Abdo, F. Sanai, M. Al-Anazi, N. Khalaf, H. Al-Humaidan, M. Al-Ahdal and F.N. Almajhdi
Besides the host immune response, genetic and environmental factors play crucial roles in the manifestation of hepatitis B virus (HBV) infection. “Regulated on activation normal T-cell expressed and secreted” factor (RANTES) plays a vital role in CD4+, CD8+ T-lymphocyte and dendritic cell activation and proliferati.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.1
- DOI:
- 10.4238/2012.April.10.1
Association between methylene tetrahydrofolate reductase and glutathione S-transferase M1 gene polymorphisms and chronic myeloid leukemia in a Brazilian population
Authors: G.S. Lordelo, A.L. Miranda-Vilela, A.K. Akimoto, P.C.Z. Alves, C.O. Hiragi, A. Nonino, M.B. Daldegan, M.N. Klautau-Guimar�£es and C.K. Grisolia
Chronic myeloid leukemia is a hematopoietic stem cell disorder that causes uncontrolled proliferation of white blood cells. Although the clinical and biological aspects are well documented, little is known about individual susceptibility to this disease. We conducted a case-control study analyzing the prevalence of the polymor.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.19.6
- DOI:
- 10.4238/2012.April.19.6
Isolation and expression analysis of the soybean GmPic gene
Authors: A.-H. Sha, H. Wu, X.-M. Fu, Q.-L. Zhang, Q.-L. Guo, Y.-H. Chen and X.-A. Zhou
The differential screening method was used to isolate the soy photoperiodic response-related genes and to further elucidate the molecular mechanisms of the soybean photoperiodic response. The light-sensitive species Zhong Dou 24 was used to receive long-time sunshine, short-time sunshine, and natural sunshine treatment. The cD.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.11.2
- DOI:
- http://dx.doi.org/10.4238/2014.June.11.2
Genetic diversity analysis of Jatropha curcas L. (Euphorbiaceae) based on methylation-sensitive amplification polymorphism
Authors: T. Kanchanaketu, N. Sangduen, T. Toojinda and V. Hongtrakul
Genetic analysis of 56 samples of Jatropha curcas L. collected from Thailand and other countries was performed using the methylation-sensitive amplification polymorphism (MSAP) technique. Nine primer combinations were used to generate MSAP fingerprints. When the data were interpreted as amplified fragment length polymorphism (.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.13.2
- DOI:
- 10.4238/2012.April.13.2
Methylation-sensitive amplified polymorphism-based genome-wide analysis of cytosine methylation profiles in Nicotiana tabacum cultivars
Authors: J. Jiao, J. Wu, Z. Lv, C. Sun, L. Gao, X. Yan, L. Cui, Z. Tang, B. Yan and Y. Jia
This study aimed to investigate cytosine methylation profiles in different tobacco (Nicotiana tabacum) cultivars grown in China. Methylation-sensitive amplified polymorphism was used to analyze genome-wide global methylation profiles in four tobacco cultivars (Yunyan 85, NC89, K326, and Yunyan 87). Amplicons with meth.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.6
- DOI:
- 10.4238/2015.November.25.6