Polymorphism
Comparative characteristics of DNA polymorphisms of �º-casein gene (CSN3) in the horse and donkey
Authors: Comparative characteristics of DNA polymorphisms of �º-casein gene (CSN3) in the horse and donkey
The aims of this study were to assess the genetic variability in the exon 1 of the κ-casein gene in four Italian horse populations (Italian Saddle horse, Italian Trotter, Italian Heavy Draught horse, and Murgese horse) and in a sample of Martina Franca donkey by estimating genotype, allele and haplotype frequencies, as well as several population gen.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.20
- DOI:
- 10.4238/2015.November.18.20
Characterization of HSP70 and its expression in tissue: correlation with physiological and immune indices in goose (Anser cygnoides) serum
Authors: W.W. Zhang, X. Xiao, J.K. Gan, X.Q. Zhang, L.N. Kong and Q.B. Luo
We cloned the goose heat shock protein 70 gene (HSP70), to determine its sequence variation and elucidate its mRNA expression. We designed primers to amplify the entire goose HSP70 sequence. We used 10 commercial Wuzong goslings in a heat-stress experiment. We collected tissue samples for RNA extraction and quantitative real-t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.17
- DOI:
- 10.4238/2015.October.9.17
Genetic variation and genetic structure of the endangered species Sinowilsonia henryi Hemsi. (Hamamelidaceae) revealed by amplified fragment length polymorphism (AFLP) markers
Authors: H. Zhang, W.L. Ji, M. Li and L.Y. Zhou
Comprehensive research of genetic variation is crucial in designing conservation strategies for endangered and threatened species. Sinowilsonia henryi Hemsi. is a tertiary relic with a limited geographical distribution in the central and western areas of China. It is endangered because of climate change and habitat fragmentati.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.14.1
- DOI:
- 10.4238/2015.October.14.1
Study of polymorphic variants of the serotonin 2A receptor gene (5-HT2A) and its possible effects on smoking habits of a population from northeastern Brazil
Authors: E.S. Ramos Neto1,2, J.O. M�¡gulas1,2, J.J.S. Sousa 1, A.C.M. Moura1, G.R. Pinto1,2, F.K.N. Yoshioka1,2, R. Canalle1,2 and F.J.N. Motta1,2
Previous studies have revealed a genetic component, including genetic polymorphisms in the serotonergic pathway, particularly in the serotonin receptor gene (5-HT2A). The aim of this study was to investigate associations of the T102C (rs6313) and A-1438G (rs6311) polymorphisms with tobacco use in a population from northeastern Brazil. We evaluated these p.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.3
- DOI:
- 10.4238/2014.October.20.3
Association between polymorphisms of fat mass and obesity-associated gene and metabolic syndrome in Kazakh adults of Xinjiang, China
Authors: Y.H. Hu, J.M. Liu, M. Zhang, R.L. Ma, H. Guo, K. Wang, J. He, Y.Z. Yan, D.S. Rui, F. Sun, L.T. Mu, Q. Niu, Y.S. Ding, J.Y. Zhang, S.G. Li and S.X. Guo
The aim of this study was to assess the association between three FTO polymorphisms (rs9939609, rs8057044, and rs1421085) and metabolic syndrome (MS)-related outcomes in the low-income, rural, nomadic minority Khazakh population in far western China. A total of 489 subjects (245 MS patients, 244 controls) were included in the study and DNA samples were ge.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.23
- DOI:
- 10.4238/2015.November.18.23
APOA5 -1131T/C polymorphism and coronary artery disease susceptibility in Chinese population: an updated meta-analysis and review
Authors: J. Zhang, D.G. Wan, H.L. Song and W.G. Zhang
Although many studies have investigated the association of the APOA5 -1131T/C polymorphism with coronary artery disease (CAD), definite conclusions have not been drawn. To understand the effects of the APOA5 -1131T/C polymorphism on the risk of developing CAD, we performed an updated meta-analysis in the Chinese population. Re.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.22
- DOI:
- 10.4238/2015.October.9.22
Effect of miR-146a polymorphism on biochemical recurrence risk after radical prostatectomy in southern Chinese population
Authors: M. Chen, Z.Y. Zhou, J.G. Chen, N. Tong, S.Q. Chen, Y. Yang, X.W. Zhang, H. Jiang, N. Liu, J. Liu, G.Z. Sha, W.D. Zhu, L.X. Hua, Z.J. Wang and B. Xu
Evidence has shown that miR-146a is involved in carcinogenesis and a common G/C variant (rs2910164) in the pre-miR-146a gene has been found to be associated with various cancers. We investigated the potential prognostic role of miR-146a polymorphism in prostate cancer after radical prostatectomy... Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.18.3
- DOI:
- 10.4238/2014.December.18.3
Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study anda meta-analysis
Authors: W.G. Hu, R.J. Pan, W. Cai, Z.T. Wang and Z.G. Zhu
The association between the human 8-oxoguanine glycosylase 1 (hOGG1) gene Ser326Cys polymorphism (rs1052133) and gastric cancer has been widely evaluated, yet a definitive answer to whether this association exists is lacking. We first conducted a case-control study to assess this association in a large Han Chinese population, and then performed a meta-ana.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.31
- DOI:
- 10.4238/2015.November.18.31
Lack of association between the vitamin D receptor polymorphism rs2228570 and chronic periodontitis in a Han Chinese population
Authors: X. Wang, T.L. Zhang and D. Chen
The vitamin D receptor (VDR) is involved in the immune response and bone metabolism, both of which are implicated in the pathogenesis of chronic periodontitis (CP). In this study, we investigated the association between the VDR single nucleotide polymorphism rs2228570 and CP susceptibility in a Han Chinese population consistin.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.18
- DOI:
- 10.4238/2015.October.9.18
KCNE1 112G>A polymorphism and atrial fibrillation risk: a meta-analysis
Authors: H.G. Han, H.S. Wang, Z. Yin, H. Jiang, M. Fang and J. Han
KCNE1, a membrane protein that spans the membrane once is responsible for modulating potassium channel functions and plays an important role in the etiology of arrhythmia. Emerging evidence indicates that a common polymorphism (112G>A; rs1805127 G>A) in the KCNE1 gene contributes to atrial fibrillation (AF) risk; however, these studies showed inconc.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.12
- DOI:
- 10.4238/2014.October.20.12