Polymorphism
Genetic characterization of the mite Varroa destructor (Acari: Varroidae) collected from honey bees Apis mellifera (Hymenoptera, Apidae) in the State of Santa Catarina, Brazil
Authors: R. Strapazzon, F.E. Carneiro, J.C.V. Guerra Jr. and G. Moretto
The mite Varroa destructor is an ectoparasite that is considered a major pest for beekeeping with European honey bees. However, Africanized bee colonies are less threatened by this ectoparasite, because infestation levels remain low in these bees. The low reproductive ability of female mites of the Japanese biotype (J), introduced to Brazil early in .. Read More»
- Genet. Mol. Res. 8(3):
- vol8-3gmr567
- DOI:
- 10.4238/vol8-3gmr567
Meta-analysis confirms that a common G/C variant in the pre-miR-146a gene contributes to cancer susceptibility and that ethnicity, gender and smoking status are risk factors
Authors: A.-X. Wang B. Xu N. Tong S.-Q. Chen Y. Yang X.-W. Zhang H. Jiang N. Liu J. Liu X.-N. Hu G.-Z. Sha M. Chen
Evidence has shown that miR-146a is involved in carcinogenesis, and a common G/C variant (rs2910164) in the pre-miR-146a gene has been associated with various types of cancer. We summarized the data from 22 published case-control studies on the association between rs2910164 and cancer risk and performed subgroup analyses by ethnicity, gender and smoking stat.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.31.2
- DOI:
- 10.4238/2012.August.31.2
Association between C807T(C/T) polymorphism of platelet glycoprotein gene and sensitivity to ischemic stroke: a meta-analysis
Authors: C. Luo, L.H. Fan, H. Zhang, J. Zhao, L. Li, L. Zhang, H.X. Zhang and M.M. Ma
Ischemic stroke can lead to loss of neurologic functions. It occurs due to obstruction in blood supply to the brain. It has been proposed that C807T(C/T) polymorphism within the platelet glycoprotein gene may be associated with density and function of glycoprotein Ia/IIa receptors and contributes to the pathogenesis of thrombo.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019416
- DOI:
- 10.4238/gmr16019416
CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer
Authors: T.D. Silva A.V. Felipe C.A.M. Pimenta K. BarĂ?£o N.M. Forones
We investigated a possible association between alcoholism, cigarette smoking, obesity and CYP2E1 RsaI and 96-bp insertion genetic polymorphisms with risk for colorectal cancer (CRC). Patients with CRC (70 women and 61 men) were matched for gender and age to 206 healthy controls. The mean age of the two groups was 62 years. Meat intake, cigarette smoking a.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.3.2
- DOI:
- 10.4238/2012.September.3.2
Role of interleukin-6 gene polymorphisms in the development of prostate cancer
Authors: C.H. Chen, M. Gong, Q.T. Yi and J.H. Guo
We investigated the role of two functional polymorphisms, IL-6-174G>C (rs1800795) and IL-6-572C>G (rs1800796), in the development of prostate cancer. A total of 212 consecutive primary prostate cancer patients and 236 control subjects were recruited between May 2012 and May 2014. The IL-6-174G>C (rs1800795) and IL-6-572C>G (rs1800796) polymorp.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.26.34
- DOI:
- 10.4238/2015.October.26.34
Significant interaction of APOE rs4420638 polymorphism with HDL-C and APOA-I levels in coronary heart disease in Han Chinese men
Authors: Y. Huang, H.D. Ye, X. Gao, S. Nie, Q.X. Hong, H.H. Ji, J. Sun, S.J. Zhou, B. Fei, K.Q. Li, J.K. Zhao, Z.P. Wang, M.Q. Xu and S.W. Duan
Apolipoprotein E (APOE) is recognized for its importance in lipoprotein metabolism and cardiovascular disease. We evaluated the association between APOE rs4420638 genotypes and circulating lipid concentrations along with the risk of coronary heart disease (CHD). We conducted a case-control study involving 1508 individuals to investigate the contribution o.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.3
- DOI:
- 10.4238/2015.October.28.3
GSTM1 polymorphism in patients with primary open-angle glaucoma
Authors: A.M. Barbosa A.B. Frare N.B. Costa R.E. Silva K.K.V.O. Moura
Primary open-angle glaucoma (POAG) is characterized by loss of retinal ganglion cells, optic nerve damage and irreversible loss of visual field. Glaucoma is the second leading cause of blindness worldwide. It was estimated that in 2010 there were about 60.5 million glaucoma cases worldwide; among these patients, 4.5 million will become bilaterally blind. .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.12.8
- DOI:
- 10.4238/2012.September.12.8
Identification and characterization of microsatellite markers from the tropical sea cucumber, Stichopus horrens (Selenka)
Authors: J.B. Shangguan, Z.B. Li, Y. Yuan and Y.S. Huang
Tropical commercial sea cucumber Stichopus horrens is extensively distributed throughout the tropical Indo-Pacific region, and wild stocks have been severely depleted over the past decade. In this study, we used the microsatellite enrichment library of S. horrens to identify and characterize 13 microsatellite loci, including 11 polymorphic loci and 2 mono.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.18
- DOI:
- 10.4238/2015.October.28.18
Application of ISSR markers for verification of F1 hybrids in mungbean (Vigna radiata)
Authors: P. Khajudparn T. Prajongjai O. Poolsawat P.A. Tantasawat
Mungbean improvement via hybridization requires the identification of true F1 hybrids from controlled crosses before further generations of selfing/crossing and selection. We utilized inter-simple sequence repeat (ISSR) markers for identifying putative F1 hybrids from six cross combinations whose morphological characteristics were very similar to those of th.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.17.3
- DOI:
- 10.4238/2012.September.17.3
Meta-analysis of epidemiological studies of association of two polymorphisms in the interleukin-10 gene promoter and colorectal cancer risk
Authors: Y.M. Zhang X.C. Zhou Z. Xu C.J. Tang
In order to make a comprehensive assessment of the potential association between two genetic variants in the IL-10 gene promoter, -1082 A>G (rs1800896) and -592 C>A (rs1800872), and colorectal cancer (CRC) risk, we conduced a meta-analysis of seven epidemiological studies, which included 1469 colorectal cancer cases and 2566 controls. Neither of the.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.7
- DOI:
- 10.4238/2012.September.25.7