Polymorphism
Association between miR-137 polymorphism and risk of schizophrenia: a meta-analysis
Authors: M.L. Ou, G. Liu, D. Xiao, B.H. Zhang, C.C. Guo, X.G. Ye, Y. Liu, N. Zhang, M. Wang, Y.J. Han, X.H. Ye, C.X. Jing and G. Yang
miR-137, a brain-enriched microRNA, is involved in the control of neuronal proliferation, differentiation, and dendritic arborization, all of which are important for proper neurogenesis and relevant to schizophrenia. miR-137 is also known to regulate many genes implicated in schizophrenia risk. Although reports have associated the miR-137 polymorphism rs1.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038703
- DOI:
- 10.4238/gmr.15038703
Predictive role of vascular endothelial growth factor polymorphisms in the survival of renal cell carcinoma patients
Authors: Y.-Q. Yang and J. Chen
We conducted a study to investigate the possible role of the vascular endothelial growth factor (VEGF) polymorphisms -2578C/A, -1154G/A and -634C/G and clinical factors in renal cell carcinoma (RCC) prognosis in a cohort of 336 RCC cases. A total of 336 patients with RCC were recruited from PLA General Hospital between January.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.16
- DOI:
- 10.4238/2014.July.4.16
Association between the CDH1-472delA and -160C>A polymorphisms and diffuse and intestinal gastric cancer in a Mexican population
Authors: A.R. Bustos-Carpinteyro, N. Delgado-Figueroa, E. Santiago-Luna, M.T. Maga�±a-Torres and J.Y. S�¡nchez-L�³pez
Gastric cancer (GC), the third leading cause of cancer-related deaths in Mexico and worldwide, can be classified into diffuse (DGC) or intestinal (IGC) types based on its histological characteristics. DGC is characterized by reduced expression of the cell adhesion protein E-cadherin, which is encoded by CDH1. The -472delA (rs5030625) and -160C>A (rs162.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038715
- DOI:
- 10.4238/gmr.15038715
Association between peptidyl arginine deiminase 4 (PADI4)-104C/T polymorphism and rheumatoid arthritis: a meta-analysis in the Chinese population
Authors: L.L. Gong, J. Chang and Y.M. Yang
The correlation between the -104C/T polymorphism in the peptidyl arginine deiminase 4 (PADI4) gene and rheumatoid arthritis (RA) risk has been analyzed in several studies. However, the results are inconclusive and remain to be confirmed in several ethnic groups. The effect of the PADI4-104C/T polymorphism on RA risk in the Chinese population was evaluated.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038750
- DOI:
- 10.4238/gmr.15038750
Polymorphisms in CYP17, COMT, and ESR1 genes in women after menopause and association with bone mineral density
Authors: C.G. Gon�§alves, B.C. Almeida, C.M. Camargo-Kosugi, A.M.M. Costa, I.D.C.G. Silva, M.A. Haidar
In this study, we evaluated genetic factors related to the mineral density during post-menopause. We evaluated 110 women in the first 5 years post-menopause, without previous hormone replacement therapy. Cytochrome P450 17 (CYP17) (rs743572), catechol-O-methyl transferase (COMT) (rs4680), and estrogen receptor 1 (ESR1) (rs9322.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.32
- DOI:
- 10.4238/2015.December.1.32
Investigation of the association between Interleukin-10 polymorphisms and risk of acute pancreatitis in a Chinese population
Authors: H.L. Jia, P.L. Sun,C.Q. Lu
We conducted a case-control study to investigate the possible association between three common single nucleotide polymorphisms in interleukin-10 (IL-10) and the development of acute pancreatitis in a Chinese population. Between January 2013 and December 2014, 255 patients with acute pancreatitis and 255 control subjects were r.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.39
- DOI:
- 10.4238/2015.December.1.39
Relationship between the HLA-G 14bp insertion/deletion polymorphism and susceptibility to autoimmune disease: a meta-analysis
Authors: S.K. Kim, K.H. Jeong,I.J. Kang, J.H. Chung, M.K. Shin, M.H. Lee
Numerous studies have investigated the potential relationship between the human leukocyte antigen (HLA)-G 14-bp insertion/deletion (INS/DEL) polymorphisms and autoimmune disease (AID). However, published results are inconclusive. Our aim was to determine whether the 14-bp INS/DEL polymorphism in the HLA-G gene contributes to t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.35
- DOI:
- 10.4238/2015.December.1.35
Role of interleukin-10 gene polymorphisms in the development of coronary artery disease in Chinese population
Authors: H.M. Xu,Y.R. Liu
The aim of this study was to investigate the association between three common SNPs (-1082A/G, -819T/C, and -592A/C) in the interleukin 10 (IL-10) gene, and the development of coronary artery disease. Between January 2013 and December 2014, 272 patients with coronary artery disease and control subjects (each) were recruited for.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.38
- DOI:
- 10.4238/2015.December.1.38
Genetic polymorphisms in TLR4, CR1 and Duffy genes are not associated with malaria resistance in patients from Baixo Amazonas region, Brazil
Authors: S.C. Soares1,4, K. Ab�©-Sandes5,6, V.B. Nascimento Filho4, F.M.F. Nunes2 and W.A. Silva Jr.2,3
The main purpose of this research was to analyze the relation of the genetic polymorphisms frequently expressed by antigen-presenting cells, erythrocytes and malaria susceptibility/resistance with the human malaria infection cases. The sample used consisted of 23 Plasmodium vivax (Pv)- and P. falciparum (Pf)-infected patients, and 21 healthy individuals a.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr439
- DOI:
- 10.4238/vol7-4gmr439
A set of novel microsatellite markers developed for an economically important tree, Dracontomelon duperreanum, in China
Authors: Z.F. Wang, H.L. Cao, L.F. Wu, Y. Guo, Q.M. Mei, M. Li, Y. Wang and Z.M. Wang
Dracontomelon duperreanum, the most representative species of the family Anacardiaceae, is an important multipurpose tree in China and Vietnam. However, no genetic diversity studies have been reported on this species. In this study, we identified 11 microsatellite markers for D. duperreanum by using the restriction-site-associ.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029578
- DOI:
- 10.4238/gmr16029578