Polymorphism
Correlation analysis between the delayed rectifier potassium channel KCNE1 (G38S) polymorphism and atrial fibrillation among the senior Uygur population in Xinjiang
Authors: N. Wugeti, G. Yu-Jun, S. Juan, A. Mahemuti
Current resources to support genetic screening among the Uygur population in Xinjiang territory for atrial fibrillation (AF) have not been well established and large-scale epidemiological analyses are needed. Using patients from the Xinjiang Uygur population as subjects, and the delayed rectifier potassium channel KCNE1 and it.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.4
- DOI:
- 10.4238/2015.December.7.4
SLC30A8 (ZnT8) variations and type 2 diabetes in the Chinese Han population
Authors: J. Xu, J. Wang and B. Chen
In recent genome-wide association studies, variants in the SLC30A8 gene have been found to be associated with risk for type 2 diabetes. We examined a possible association of tag SNPs spanning SLC30A8 and their haplotypes with type 2 diabetes in the Chinese Han population. There were 1508 Chinese Han type 2 diabetes patients an.. Read More»
- Genet. Mol. Res. 11(2):
- dx.doi.org/2012.May.24.1
- DOI:
- dx.doi.org/10.4238/2012.May.24.1
Association of the GSTT1 polymorphism in upper aerodigestive tract cancer with tobacco smoking
Authors: T.M. Silva, C.R. Marques, M.F. Marques Filho, A.B. Marques,G. Di Pietro and F. Rios-Santos
Polymorphisms in genes encoding xenobiotic-metaboli- zing enzymes might explain differences in the susceptibility to upper aerodigestive tract (UADT) cancers in individuals exposed to tobacco or other carcinogens. The present study aimed to evaluate the association of polymorphisms in the glutathione S-transferase (GST) candid.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.22
- DOI:
- 10.4238/2014.January.21.22
Role of VEGF gene polymorphisms in the clinical outcome of non-small cell lung cancer
Authors: N. Chen, C.N. Ma, M. Zhao, Y.J. Zhang
This report details a study conducted to assess the role of VEGF gene polymorphisms in the prognosis of advanced non-small cell lung carcinoma (NSCLC). Samples obtained from 210 advanced NSCLC patients admitted at the Huaihe Hospital of Henan University between January 2010 and December 2011 were recruited for this study. The .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.13
- DOI:
- 10.4238/2015.December.7.13
Association of tumor necrosis factor-�± 308G/A polymorphism with urogenital cancer risk: a systematic review and meta-analysis
Authors: J. Cai,M.Y. Yang, N. Hou, X. Li
We integrated all the eligible studies and investigated whether the TNF-α 308G/A polymorphism correlates with urogenital cancer risk. Tumor necrosis factor-α (TNF-α) is a risk factor for some urogenital cancers; however, in prostate and bladder cancers the results are controversial. PubMed, EMBASE, Web of Sci.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.22
- DOI:
- 10.4238/2015.December.7.22
Association between adiponectin gene T45G polymorphism and nonalcoholic fatty liver disease risk: a meta-analysis
Authors: W. Zhang1, L.Q. Zhu1, X.L. Huo2, J. Qin2 and G.Y. Yuan3
Numerous epidemiological investigations have evaluated the association between adiponectin gene T45G polymorphism and risk of nonalcoholic fatty liver disease (NAFLD). However, the results of these studies have proven to be inconsistent. Therefore, we conducted a meta-analysis to obtain a more accurate estimation of this association. Published articles we.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017190
- DOI:
- 10.4238/gmr.15017190
CYP4F2 gene single nucleotide polymorphism is associated with ischemic stroke
Authors: H.-Q. Yan, Y. Yuan, P. Zhang, Z. Huang, L. Chang and Y.-K. Gui
The objective of this study was to explore the relationship between CYP4F2 gene polymorphism and ischemic stroke (IS) in the Han Chinese population. We performed a case-control study to genotype four single nucleotide polymorphisms (SNPs) (rs2108622, rs3093100, rs3093105, rs3093135) in the CYF4F2 gene. The genotype and haplotype distributions were compare.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.8
- DOI:
- 10.4238/2015.January.30.8
Association of the ApoE gene polymorphism and dietary factors with cerebral infarction and circulating lipid concentrations
Authors: H.-Q. Yan, Y. Yuan, P. Zhang, Z. Huang, L. Chang and Y.-K. Gui
The aim of this study was to explore the relationship between the ApoE gene polymorphism and dietary factors with stroke and circulating lipid levels in the Chinese population. We selected 580 patients with stroke and 580 age- and gender-matched healthy controls, and examined their ApoE polymorphism genotype using the polymerase chain reaction-restriction.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.9
- DOI:
- 10.4238/2015.January.30.9
Genetic variations in the IGF-IGFR-IGFBP axis confer susceptibility to lung and esophageal cancer
Authors: X.P. Huang, W.H. Zhou and Y.F. Zhang
Recent evidence suggests that genetic variations in the insulin-like growth factor (IGF)-IGF receptor (IGFR)-IGF binding proteins (IGFBP) axis may impact an individual’s susceptibility to lung and esophageal cancer, but individually published results are inconclusive. Our meta-analysis aimed at providing a more precise e.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.24.17
- DOI:
- 10.4238/2014.January.24.17
Screening of molecular markers linked to dwarf trait in crape myrtle by bulked segregant analysis
Authors: Y.J. Ye, Y. Liu, M. Cai, D. He, J.S. Shen, Y.Q. Ju, X.M. Bian,H.T. Pan and Q.X. Zhang
Plant height is one of the most important traits of plant architecture as it modulates both economic and ornamental values. Crape myrtle (Lagerstroemia indica L.) is a popular ornamental woody plant because of its long-lasting mid-summer bloom, rich colors, and diversified plant architecture. These traits also make it an ideal model of woody species for g.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.30.10
- DOI:
- 10.4238/2015.April.30.10