Polymorphism
Lack of association between the aryl hydrocarbon receptor rs2066853 polymorphism and breast cancer: A meta-analysis on Ahr polymorphism and breast cancer
Authors: Y. Li, H.Z. Qin, Q. Song, X.D. Wu and J.H. Zhu
Published data regarding the association between aryl hydrocarbon receptor (Ahr) rs2066853 polymorphism and the risk of breast cancer shows conflicting results. We performed a meta-analysis on 2999 patients and 3050 controls from three related case-control studies to estimate the association between Ahr rs2066853 polymorphism and the risk of breast cancer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Estrogen receptor alpha gene PvuII polymorphism and risk of fracture in postmenopausal women: a meta-analysis
Authors: W. Deng, J.C. Han, L. Chen and W.L. Qi
Numerous studies have evaluated the association between estrogen receptor alpha (ESR1) gene PvuII polymorphism and fracture risk in postmenopausal women. However, the results have been inconsistent. We performed a meta-analysis to examine the association between the ESR1 gene PvuII polymorphism and fracture risk in postmenopausal women. Studies published fro.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.8
- DOI:
- 10.4238/2015.February.13.8
Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers
Authors: Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers
Thyroid hormones play an important role in regulating metabolism and can affect metabolism-related traits such as fat deposition. The thyroglobulin (TG) gene produces the precursor of thyroid hormones and has been proposed as a candidate gene for a quantitative trait locus with an effect on fat deposition. In this study, we identified 4 novel single nucle.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.2
- DOI:
- 10.4238/2015.May.22.2
Association between C1GALT1 variants and genetic susceptibility to IgA nephropathy in Uygur
Authors: W.L. Li and C. Lu
Immunoglobulin A (IgA) nephropathy (IgAN) is a common form of primary glomerulonephritis characterized by diffuse glomerular mesangial IgA1 deposition leading to mesangial proliferation and chronic glomerular inflammation. Analyses of serum IgA1 from IgAN patients revealed abnormal galactosylation of the O-linked carbohydrate moieties of IgA that may resu.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.3
- DOI:
- 10.4238/2015.May.22.3
Type II deiodinase polymorphisms and serum thyroid hormone levels in patients with mild cognitive impairment
Authors: M. Luo, X.H. Zhou, T. Zou, K. Keyim and L.M. Dong
We investigated type II deiodinase (DIO2 ) polymorphisms and serum thyroid hormone levels in subjects with mild cognitive impairment (MCI) in a Uygur population. We studied the DIO2 Thr92Ala (rs225014) and ORFa-Gly3Asp (rs12885300) polymorphisms of 129 unrelated MCI cases and 131 matched controls. All subjects were genotyped using SNaPshot SNP genotyping.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.10
- DOI:
- 10.4238/2015.May.22.10
Effectiveness of microsatellite and single nucleotide polymorphism markers for parentage analysis in European domestic pigs
Authors: G.C. Yu, Q.Z. Tang, K.R. Long, T.D. Che, M.Z. Li and S.R. Shuai
Parentage analysis and individual identification are recent, promising methods that have been applied to evolutionary and ecological studies, as well as conservation management. Parental exclusion relying on polymorphic microsatellites has been used worldwide in parentage determination, while the low mutation rate and genotyping error rate of single nucleoti.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.15
- DOI:
- 10.4238/2015.February.13.15
Association between GSTM1 polymorphisms and lung cancer: an updated meta-analysis
Authors: H. Liu, H.F. Ma and Y.K. Chen
The relationship between glutathione S-transferase M1 (GSTM1) genetic polymorphisms and lung cancer has been reported previously. However, the results are not consistent. Therefore, to clarify the association between GSTM1 polymorphisms and lung cancer, we performed a meta-analysis based on published studies. We used the Revman 5.0 software to perform lit.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.17
- DOI:
- 10.4238/2015.February.13.17
Analysis of the genetic effects of CAPN1 gene polymorphisms on chicken meat tenderness
Authors: J.T. Shu, M. Zhang, Y.J. Shan, W.J. Xu, K.W. Chen and H.F. Li
The micromolar calcium-activated neutral protease gene (CAPN1) is a physiological candidate gene for meat tenderness. Four previously identified single nucleotide polymorphism (SNP) markers located within the CAPN1 gene were evaluated for their associations with variation in the meat tenderness of a Chinese indigenous chicken breed, a higher meat quality .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.18
- DOI:
- 10.4238/2015.February.13.18
Investigation on the association between NLRP3 gene polymorphisms and susceptibility to primary gout
Authors: L.F. Wang, Y.J. Ding, Q. Zhao, X.L. Zhang
We conducted a case-control study to investigate the association between 3 common NALP3 polymorphisms (rs10754558, rs7512998, and rs12137901) and the susceptibility to primary gout. A total of 320 patients with primary gout and 320 controls were included in this study. The genotyping of NALP3 rs10754558, rs7512998, and rs12137901 were conducted by polymer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.
- DOI:
- 10.4238/2015.
Association between MTHFR 677C/T and 1298A/C gene polymorphisms and breast cancer risk
Authors: X.F. Zhang, T. Liu, Y. Li and S. Li
ABSTRACT. We performed a case-control study to investigate the association between single nucleotide polymorphisms in the MTHFR gene (677C/T and 1298A/C) and risk of breast cancer. This case-control study included 216 breast cancer cases and 216 controls. The MTHFR 677C/T and 1298A/C gene polymorphisms were assessed by polymerase chain reaction restrictio.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015