Polymorphism
Genetic variability among natural populations of Zaprionus indianus (Drosophilidae) in the States of S�£o Paulo and Minas Gerais, Brazil
Authors: D. Braganholi, M. B�©lo, B.W. Bertoni, A.L. Fachin, R.O. Beleboni and S.M. Zingaretti
Random amplified polymorphic DNA (RAPD) was used to detect polymorphisms among Zaprionus indianus fly populations collected from six municipalities in the States of São Paulo and Minas Gerais, Brazil. This species is an important, recently introduced fruit fly pest of figs and other fruit. Among 21 primers, 16 produced .. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr879
- DOI:
- 10.4238/vol9-3gmr879
Genetic differences between strains of Biomphalaria glabrata (Planorbidae) that are susceptible and unsusceptible to schistosomiasis
Authors: A.L.D. Oliveira, D. Da Silva, B.C. Manzano, A.Z. Abdel-Hamid, M.Y. Marcelino, E.M. Zanotti-Magalh�£es, L.A. Magalh�£es and J.T. Ribeiro-Paes
Despite the implementation control programs, schistosomiasis continues to spread throughout the world. Among modern control strategies, vector control is currently being emphasized. Within this context, analysis of the genetic variability of intermediate host snails (Biomphalaria spp) is important because it allows identificat.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr821
- DOI:
- 10.4238/vol9-3gmr821
Frequency of ABO blood group system polymorphisms in Plasmodium falciparum malaria patients and blood donors from the Brazilian Amazon region
Authors: D.B. Carvalho, L.C. de Mattos, W.C. Souza-Neiras, C.R. Bonini-Domingos, A.B. C�³simo, L.M. Storti-Melo, G.C. Cassiano, A.A.A. Couto, A.J. Cordeiro, A.R.B. Rossit and R.L.D. Machado
We investigated the ABO genotypes and heterogeneity of the O alleles in Plasmodium falciparum-infected and non-infected individuals from the Brazilian Amazon region. Sample collection took place from May 2003 to August 2005, from P. falciparum malaria patients from four endemic regions of the Brazilian Amazon. The control grou.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr803
- DOI:
- 10.4238/vol9-3gmr803
Correlation between polymorphisms in the IL-17A and IL-17F genes and development of coronary artery disease
Authors: G.Y. Geng, H.L. Liu, Y.J. Zhao, L. Wu, L. Mao and N. Ba
A case-control study was conducted to investigate the association between genetic variants of IL-17A rs2275913 and IL-17F rs763780 and the development of coronary artery disease (CAD) in a Chinese population. A total of 306 individuals with CAD and 306 unaffected individuals were enrolled from the Zhengzhou People’s Hospital between May 2012 and May.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.25.15
- DOI:
- http://dx.doi.org/10.4238/2015.September.25.15
Investigation of the effects of single-nucleotide polymorphisms in DNA repair genes on the risk of glioma
Authors: K. Gao, S.Q. Mu and Z.X. Wu
Several single-nucleotide polymorphisms (SNPs) in DNA repair gene have been shown to affect DNA repair and to modify susceptibility to cancer. In this study, to investigate the role of these SNPs in glioma, we examined the potential association of 14 SNPs in DNA repair genes with the glioma risk in a Chinese population. We inc.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.27.5
- DOI:
- http://dx.doi.org/10.4238/2014.February.27.5
Polymorphisms of +2836 G>A in the apoE gene are strongly associated with the susceptibility to essential hypertension in the Chinese Hui population
Authors: Y. Yang, J.R. Xu, X.M. Liu, J. Zhou, B. Yang, M. Li and Y.J. Wang,
In the present study, the correlation of polymorphisms of the apolipoprotein E (apoE) gene with the susceptibility of essential hypertension (EH) was investigated. Single nucleotide polymorphisms of the apoE gene at the -491 A>T, +969 C>G, and +2836 G>A sites were determined in 221 non-EH individuals and 109 subjects .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.27.6
- DOI:
- http://dx.doi.org/10.4238/2014.February.27.6
Association of -619C/T polymorphism in CDSN gene and psoriasis risk: a meta-analysis
Authors: Y. Wu, B. Wang, J.L. Liu, X.H. Gao, H.D. Chen and Y.H. Li
Previous studies investigating the association between corneodesmosin (CDSN) polymorphisms and psoriasis risk have provided inconsistent results. The aim of our study was to clarify the effects of CDSN -619C/T polymorphism on psoriasis risk by conducting a meta-analysis. We conducted searches of the published literature in Pub.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.21.6
- DOI:
- 10.4238/2011.October.21.6
Meta-analysis of an association of codon 72 polymorphisms of the p53 gene with increased endometrial cancer risk
Authors: Y. Gu, X. Zhou and S.L. Zhang
Polymorphisms of the p53 gene have been associated with susceptibility to endometrial cancer. However, whether there is a specific association is still controversial. We investigated a possible association between p53 codon 72 polymorphism and endometrial cancer risk by conducting a meta-analysis. Publications addressing this .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.11
- DOI:
- 10.4238/2011.October.31.11
Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: a meta-analysis
Authors: L.P. Zhou, H. Luan, X.H. Dong, G.J. Jin, D.L. Man and H. Shang
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in a number of pathologic processes, including angiogenesis, tumor growth and metastasis. Polymorphisms of the VEGF gene have been associated with susceptibility to colorectal cancer (CRC). However, the specific association still remains.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.13
- DOI:
- 10.4238/2011.October.31.13
Influence of glutathione S-transferase polymorphisms on type-2 diabetes mellitus risk
Authors: M.A. Amer, M.H. Ghattas, D.M. Abo-ElMatty and S.H. Abou-El-Ela
Glutathione S-transferase (GST) protects cells against oxidative stress. We evaluated the effect of genetic polymorphisms of the GST gene family on the risk of developing type-2 diabetes mellitus and on glycemic control. We also investigated the effects of smoking combined with these polymorphisms on type-2 diabetes mellitus r.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.14
- DOI:
- 10.4238/2011.October.31.14