Polymorphism
CYP1A2 polymorphism in Chinese patients with acute liver injury induced by Polygonum multiflorum
Authors: K.F. Ma, X.G. Zhang and H.Y. Jia
The objective of this study was to evaluate the genotype and allelic frequencies of CYP1A2 in Chinese patients with acute liver injury induced by Polygonum multiflorum. We examined the clinical mechanism of acute liver injury induced by P. multiflorum. According to the diagnostic criteria for drug-induced liv.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.19
- DOI:
- 10.4238/2014.July.25.19
XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress
Authors: O. �°sbir, U. G�¶rm�¼��, H.A. Ergen, B. ��akmako��lu, ��.T. Kahraman and N. Baykan
Knee replacement surgery is an ischemia/reperfusion model, as it uses tourniquet applied to the knee area to stop the blood flow during the operation. Fifty patients that were undergoing elective arthroscopic knee surgery were included in our study. Human 8-oxoguanine glycosylase 1 (hOGG1) is an enzyme to repair specific DNA l.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.19.4
- DOI:
- 10.4238/2011.December.19.4
HIF1A gene Pro582Ser polymorphism and susceptibility to digestive tract cancers: a meta-analysis of case-control studies
Authors: J. Xu, L. Xu, L.T. Li, Q. You, L.S. Cha
Many existing studies have demonstrated that common polymorphisms in the hypoxia inducible factor-1α (HIF-1A) may contribute to the development of digestive tract cancers, but individually published studies showed inconclusive results. This meta-analysis aimed to derive a precise estimation of the relationships between H.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.29
- DOI:
- 10.4238/2014.July.25.29
Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population
Authors: X.P. Hu, Z.Q. Li, J.Y. Zhou, Z.H. Yu, J.M. Zhang and M.L. Guo
Environmental influences on the development and progression of dental caries are well known; however, there is little evidence of a genetic component imparting susceptibility to dental caries. The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibi.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.15
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.15
Isolation and characterization of novel microsatellite markers from the sika deer (Cervus nippon) genome
Authors: Y.M. Li, C.Y. Bai, W.P. Niu, H. Yu, R.J. Yang, S.Q. Yan, J.Y. Zhang, M.J. Zhang and Z.H. Zhao
Microsatellite markers are widely and evenly distributed, and are highly polymorphic. Rapid and convenient detection through automated analysis means that microsatellite markers are widely used in the construction of plant and animal genetic maps, in quantitative trait loci localization, marker-assisted selection, identification of genetic relationships, .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.September.28.4
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.4
Genetic diversity of Qatari date palm using SSR markers
Authors: K. Elmeer and I. Mattat
The genetic diversity in the date palm germplasm of 59 female accessions representing 12 cultivars from different locations in Qatar was investigated using 14 loci of simple-sequence repeat (SSR) primers. A total of 94 alleles, with a mean of 6.7 alleles per locus, were scored. The number of alleles per locus varied from 3 (primer mPdCIR090) to 11.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.6.9
- DOI:
- 10.4238/2015.March.6.9
Meta-analysis of epidemiological studies of association of P53 codon 72 polymorphism with bladder cancer
Authors: D.B. Li, X. Wei, L.H. Jiang, Y. Wang and F. Xu
Although there have been many studies investigating a possible association between p53 codon 72 polymorphism and risk of bladder cancer, the results have been inconsistent. We conducted a meta-analysis of six epidemiological studies, which included 597 bladder cancer cases and 731 controls. Patients with bladder cancer had a s.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr882
- DOI:
- 10.4238/vol9-3gmr882
Correlation analysis of the PNPLA7 gene polymorphism and susceptibility to menstrual disorder
Authors: Y. Su, G.L. Kong, Y.L. Su, Y. Zhou, L.F. Lv, Q. Wang, B.P. Huang,R.Z. Zheng, Q.Z. Li, H.J. Yuan and Z.G. Zhao
We examined the correlation between PNPLA7 gene polymorphisms at the rs61754920 and rs11137410 loci and menstrual disorder in women of reproductive age in the Central Plain. Genomic DNA was extracted from peripheral blood; polymerase chain reaction-ligase detection reaction and SNaPshot genotyping were used to detect polymorphisms in the rs61754920 and rs.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.6.20
- DOI:
- 10.4238/2015.March.6.20
Association between the LXR�± polymorphism and stroke in a Chinese population
Authors: J.S. Yang, J.J. Hao, S.S. Wang, Z.F. Zhu, Q. Fang, H. Bao and H.P. Zhang
We examined the relationship between the liver X receptor α gene (LXRα) polymorphism and the susceptibility to stroke. We utilized the single fluorescent-labeled probe technique to detect the genotype of rs12221497 in the LXRα gene in 400 stroke patients and 400 healthy control subjects. The difference in genotype distribution between th.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.13.2
- DOI:
- 10.4238/2015.March.13.2
Identification and analysis of phospholipid transfer protein polymorphisms and their association with marbling score in Hanwoo (Korean cattle)
Authors: J. Seong, J.D. Oh, H.K. Lee, G.J. Jeon and H.S. Kong
Phospholipid transfer protein (PLTP) regulates high-density lipoprotein metabolism. The gene encoding PLTP is located on bovine chromosome 13. The objective of this study was to identify single nucleotide polymorphisms (SNPs) in the Hanwoo (Bos taurus coreanae) PLTP gene to detect novel mutations affecting economically important traits. Five SNPs were ide.. Read More»
- Genet. Mol. Res. 12(1):
- 2013
- DOI:
- 10.4238/2013