All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Polymorphism

Animal Genetics   Research Article

Development of swine-specific DNA markers for biosensor-based halal authentication

Authors: M.E. Ali, U. Hashim, M. Kashif, S. Mustafa, Y.B. Che Man and S.B. Abd Hamid

The pig (Sus scrofa) mitochondrial genome was targeted to design short (15-30 nucleotides) DNA markers that would be suitable for biosensor-based hybridization detection of target DNA. Short DNA markers are reported to survive harsh conditions in which longer ones are degraded into smaller fragments. The whole swine mitochondr.. Read More»

Genet. Mol. Res. 11(2):
http://dx.doi.org/2012.June.29.9
DOI:
http://dx.doi.org/10.4238/2012.June.29.9
Medical Genetics   Research Article

Association between single-nucleotide polymorphisms of fatty acid synthase gene and meat quality traits in Datong Yak (Bos grunniens).

Authors: M. Chu, X.Y. Wu, X. Guo, J. Pei, F. Jiao, H.T. Fang,C.N. Liang X.Z. Ding, P.J. Bao and P. Yan

Fatty acid synthase (FASN) is a key enzyme in fatty acid anabolism that plays an important role in the fat deposit of eukaryotic cells. Therefore, in this study, we detected 2 novel single-nucleotide polymorphisms (SNPs) in the FASN gene in 313 adult individuals of Datong yak using polymerase chain reaction-single strand conformation polymorphism and DNA .. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.21
DOI:
http://dx.doi.org/10.4238/2015.March.30.21
Cytogenomics   Research Article

Vascular endothelial growth factor gene 1154 G/A, 2578 C/A, 460 C/T, 936 C/T polymorphisms and association with recurrent pregnancy losses

Authors: H. ��aml�±, B.��. Demir, A. ��zg�¶z, M.A. Atalay and G. Uncu

Vascular endothelial growth factor (VEGF) regulates endothelial cell proliferation, migration and differentiation. VEGF plays a critical role in angiogenesis during placenta formation. We investigated whether VEGF gene polymorphisms are associated with recurrent pregnancy loss. Thirty-eight women with recurrent pregnancy loss and 30 control women with liv.. Read More»

Genet. Mol. Res. 11(4):
2012.December.17.6
DOI:
10.4238/2012.December.17.6
Human Genetics   Research Article

Effect of a pre-microRNA-149 (miR-149) genetic variation on the risk of ischemic stroke in a Chinese Han population

Authors: Q.Y. Chen, N. Liu, J. Ma, Y. Fang, Y. Cao, H. Li and Y.C. Liu

Clinical and experimental data have demonstrated that genetic factors play an important role in determining the susceptibility to ischemic stroke (IS). The present study was performed to clarify the association between the pre-microRNA-149 (miR-149) single nucleotide polymorphism rs71428439 and the risk of IS in the Jiangsu Han population. Polymerase chai.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.17
DOI:
http://dx.doi.org/10.4238/2015.March.30.17
Medical Genetics   Research Article

Cyclin D1 G870A polymorphism is associated with an increased risk of multiple myeloma

Authors: S. Wang, Y. Huang, R. Su, Z. Fang and M. Han

Cyclin D1 is an important cell cycle regulator implicated in the pathogenesis of many cancer types. In particular, translocation and overexpression of cyclin D1 are common events in multiple myeloma (MM), suggesting that it may drive the initiation and progression of this malignancy. However, the association between genetic polymorphisms of cyclin D1 and .. Read More»

Genet. Mol. Res. 14(2):
2015.June.1.2
DOI:
10.4238/2015.June.1.2
Plant Genetics   Research Article

Evaluation of the genetic diversity of Bupleurum using amplified fragment length polymorphism analysis

Authors: S.Y. Ke, L.L. Shi, Y.Z. Ma and X.J. Zhou

Radix bupleuri (Chaihu), the dried root of the Bupleurum plant, is an important component of traditional Chinese medicine. In this study, we examined the genetic diversity of 11 Bupleurum strains, originating from 7 provinces in China, using amplified fragment length polymorphism analysis. A total of 274 polymorphic bands were obtained using 6 primer comb.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.18
DOI:
http://dx.doi.org/10.4238/2015.March.30.18
Human Genetics   Research Article

Meta-analysis demonstrates association between Arg72Pro polymorphism in the P53 gene and susceptibility to keloids in the Chinese population

Authors: Y. Wu, B. Wang, Y.H. Li, X.G. Xu, Y.J. Luo, J.Z.S. Chen, H.C. Wei, X.H. Gao and H.D. Chen

Although there is evidence suggesting genetic susceptibility for keloids, studies investigating the association between Arg72Pro polymorphism in the P53 gene and tendency to form keloids have given variable results. We made a meta-analysis of the effects of P53 Arg72Pro polymorphism on keloid risk in the Chinese population by .. Read More»

Genet. Mol. Res. 11(2):
http://dx.doi.org/2012.June.29.2
DOI:
http://dx.doi.org/10.4238/2012.June.29.2
Human Genetics   Research Article

Influence of interleukin-18 gene polymorphisms on acute pancreatitis susceptibility in a Chinese population

Authors: H.B. Gui, X.G. Du, Z.H. Fu and X.M. Chen

We investigate the relationship between IL-18 -607C/A and -137G/C genetic polymorphisms and development of acute pancreatitis in a Chinese population. A total of 153 patients were consecutively recruited from the First Affiliated Hospital of Chongqing Medical University between January 2013 and November 2014. Genotyping of IL-.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038394
DOI:
10.4238/gmr.15038394
Medical Genetics   Research Article

Association between TNF-�± rs1800629 polymorphism and the risk of myocardial infarction: A meta-analysis

Authors: X.P. Hua, J. Qian, C.B. Cao, J. Xie, X.T. Zeng and Z.J. Zhang

The tumor necrosis factor-alpha (TNF-α) G-308A polymorphism has been suggested to be a susceptibility factor for myocardial infarction (MI). However, differing results from various studies have led to controversial conclusions. Hence, we performed a meta-analysis to evaluate the association between TNF-α G-308A pol.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037292
DOI:
10.4238/gmr.15037292
Human Genetics   Research Article

Role of IL-6 polymorphism on the development of cardiovascular events and coronary artery disease in patients receiving hemodialysis

Authors: Y. Song, H.D. Gu, Y. He and J.W. Wang

We aimed to investigate the role of IL-6 polymorphism on the development of cardiovascular events and coronary artery disease in patients receiving hemodialysis. Blood samples were collected from 216 patients receiving hemodialysis treatment. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to genotype IL-6 -634C/G, -.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.23
DOI:
http://dx.doi.org/10.4238/2015.March.30.23