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Promoter

Human Genetics   Short communication

Mitochondrial sirtuins in cancer

Authors: Mitochondrial sirtuins in cancer

All living beings require energy and the ultimate source for this energy in eukaryotes are mitochondria – originally an organelle of bacterial origin and eventually incorporated into the cytoplasm. Mitochondrial bioenergetics and dynamics are essential for the maintenance of cellular and metabolic homeostasis and any imbalance can result in diseases.. Read More»

Genet. Mol. Res. 20(6):
Human Genetics   Editorials

A brief study about DNA polymerase

Authors: Mohammad irani hafeez

Ribonucleases (RNases) are key players of the host immunity and contribute to maintaining tissue homeostasis and body fluid sterility. Secreted upon a diversity of cellular injuries, they mediate signaling processes, and have been classified as alarmins. Recent literature reveals how the immune response system uses common strategies to fight both cance.. Read More»

Genet. Mol. Res. 20(6):
Human Genetics   Short communication

Lac operon: It's structure and function

Authors: Stephan Morris*

Early bits of knowledge into components of transcriptional guideline came from investigations of E. coli by scientists Francois Jacob and Jacques Monod. In E. coli, and numerous different microscopic organisms, qualities encoding a few distinct proteins might be situated on a solitary record unit called an operon. The qualities in an operon share the equi.. Read More»

Genet. Mol. Res. 20(4):
Animal Genetics   Research Article

Promoter identification and analysis of key glycosphingolipid biosynthesis-globo series pathway genes in piglets

Authors: W.Y. Qin, L.N. Gan, R.W. Xia, W.H. Dong, S.Y. Sun, G.Q. Zhu,S.L. Wu and W.B. Bao

Glycosphingolipid biosynthesis-globo series pathway genes (FUT1, FUT2, ST3GAL1, HEXA, HEXB, B3GALNT1, and NAGA) play an important regulatory role in the defense against Escherichia coli F18 in piglets. In this study, we identified the transcription initiation site and promoter of this gene cluster by mined previous RNA-seq res.. Read More»

Genet. Mol. Res. 16(2):
gmr16029574
DOI:
10.4238/gmr16029574
Plant Genetics   Research Article

TaALMT1 promoter sequence compositions, acid tolerance, and Al tolerance in wheat cultivars and landraces from Sichuan in China

Authors: C. Han1*, S.F. Dai1*, D.C. Liu1, Z.J. Pu2, Y.M. Wei1, Y.L. Zheng1, D.J. Wen1, L. Zhao1 and Z.H. Yan1

Previous genetic studies on wheat from various sources have indicated that aluminum (Al) tolerance may have originated independently in USA, Brazil, and China. Here, TaALMT1 promoter sequences of 92 landraces and cultivars from Sichuan, China, were sequenced. Five promoter types (I', II, III, IV, and V) were observed in 39 cultivars, and only three promot.. Read More»

Genet. Mol. Res. 12(4):
2013.November.18.9
DOI:
10.4238/2013.November.18.9
Human Genetics   Research Article

Influence of the human MIF promoter polymorphism on hepatocellular carcinoma prognosis

Authors: T. Yuan, C. Tang, M. Chen, S. Deng and P. Chen

Hepatocellular carcinoma (HCC) is one of the most common worldwide malignancies. A relative complete diagnosis system for primary carcinoma of liver has already been established, but the surgical prognosis for HCC, which depends mainly on postoperative pathological classification and data of recurrence and metastasis, lacks valid experimental indicators. .. Read More»

Genet. Mol. Res. 12(4):
2013.January.4.3
DOI:
10.4238/2013.January.4.3
Microbial Genetics   Research Article

Aberrant promoter methylation of the CD4 gene in peripheral blood cells of mastitic dairy cows

Authors: X.S. Wang, Y. Zhang, Y.H. He, P.P. Ma, L.J. Fan, Y.C. Wang,Y.I. Zhang, D.X. Sun, S.L. Zhang, C.D. Wang, J.Z. Song and Y. Yu

Bovine mastitis is the most common and costly disease of dairy cattle. Cluster of differentiation 4 (CD4) is closely related to the immune response in mastitis. We quantified promoter CpG methylation levels of the CD4 gene in Chinese Holsteins with clinical mastitis (CM) and in healthy controls; these levels were quantitatively detected with bisulfite pyr.. Read More»

Genet. Mol. Res. 12(4):
2013.December.4.10
DOI:
10.4238/2013.December.4.10
Animal Genetics   Research Article

Identification and analysis of a 5-bp indel of a porcine BMP7 gene promoter

Authors: P. Lu, X. Feng, J.S. Zhou, X.B. Liu, Q.X. Chen and M. Li

Bone morphological protein7 (BMP7), a member of the transforming growth factor-β (TGF-β) family, was first identified because of its ability to induce ectopic chondro-osteogenesis in vivo. It also plays a crucial role in the growth, development, and physiological functioning of the reproductive system. Among intra-ov.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.9.19
DOI:
http://dx.doi.org/10.4238/2014.June.9.19
Plant Genetics   Research Article

Cloning and functional analysis of the chitinase gene promoter in peanut

Authors: X.L. Chen, R.T. Song, M.Y. Yu, J.M. Sui, J.S. Wang and L.X. Qiao

Chitinase is an important pathogenesis-related protein in plants, and it can accumulate when induced by salicylic acid (SA) or other elicitors. Here, we found that chitinase mRNA levels were 4.5-times greater when peanut seedlings were sprayed with 1.5 mM SA, as compared to water. The upstream promoter sequence of the chitinas.. Read More»

Genet. Mol. Res. 14(4):
2015.October.19.15
DOI:
10.4238/2015.October.19.15
Cytogenomics   Research Article

Construction of the intermediate vector pVBG2307 by incorporating vital elements of expression vectors pBI121 and pBI221

Authors: S.S. Ahmed Z.-H. Gong J.-J. Ji Y.-X. Yin H.-J. Xiao M.A. Khan A. Rehman I. Ahmad

Molecular chaperones of plasmid pBI121 carrying CaMV35S promoter and a nucleotide sequence of plasmid pBI221 were inserted into plasmid pCAMBIA2300 to construct an intermediate vector: pVBG2307. This novel vector pVBG2307 contains a greatly expanded multiple cloning site with an adjacent imported CaMV35S promoter sequence. This vector allows controlled tr.. Read More»

Genet. Mol. Res. 11(3):
2012.August.31.7
DOI:
10.4238/2012.August.31.7