Regeneration
Branches of the NF-�ºB signaling pathway regulate proliferation of oval cells in rat liver regeneration
Authors: W.M. Zhao, Y.L. Qin, Z.P. Niu, C.F. Chang, J. Yang, M.H. Li, Y. Zhou and C.S. Xu1,
The NF-kB (nuclear factor kB) pathway is involved in the proliferation of many cell types. To explore the mechanism of the NF-kB signaling pathway underlying the oval cell proliferation during rat liver regeneration, the Rat Genome 230 2.0 Array was used to detect expression changes of NF-kB signaling pathway-related genes in .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017750
- DOI:
- 10.4238/gmr.15017750
Impact of cold ischemia on cytokines after partial liver transplantation in rats
Authors: Q.-A. Qi, Z.-Y. Yang, K.-S. Ma, Q. Lu, S.-G. Wang, X.-W. Li, F. Xia, W. Liu and P. Bie
To study the impact of cold ischemia on tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10) expression after liver transplantation, a stable model of partial liver transplantation in rats was established. The experimental animals were divided into the following groups: a partial hepatectomy control group, a group that received partial liv.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.27.1
- DOI:
- 10.4238/2013.September.27.1
Tetradecyl 2,3-dihydroxybenzoate promotes functional recovery after spinal cord injury in adult rats
Authors: Y.M. Ding, J.Y. Zhu, S.J. Zhang, S.S. Zhang, C. Wang, L.L. Wang and X. Zhang
Tetradecyl 2,3-dihydroxybenzoate (ABG001) is a small molecule separated from gentian extract that has a similar effect to nerve growth factor. It is not clear whether it can promote functional recovery in animals suffering from a central nervous system injury. In order to explore the role of ABG001 in restoration of tissue str.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028653
- DOI:
- 10.4238/gmr.15028653
Improved Agrobacterium-mediated transformation and high efficiency of root formation from hypocotyl meristem of spring Brassica napus �Precocity� cultivar
Authors: X.X. Liu, S.R. Lang, L.Q. Su, X. Liu and X.F. Wang
Rape seed (Brassica napus L.) is one of the most important oil seed crops in the world. Genetic manipulation of rapeseed requires a suitable tissue culture system and an efficient method for plant regeneration, as well as an efficient transformation procedure. However, development of transgenic B. napus has been problematic, and current studies are limite.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.14.11
- DOI:
- 10.4238/2015.December.14.11
MicroRNA-21 promotes proliferation of rat hepatocyte BRL-3A by targeting FASLG
Authors: J.J. Li,W.H. Chan,W.Y. Leung,Y. Wang and C.S. Xu
Rat liver regeneration (RLR) induced by partial hepatectomy involves cell proliferation regulated by numerous factors, including microRNAs (miRNAs). miRNA high-throughput sequencing has been established and used to analyze miRNA expression profiles. This study showed that 39 miRNAs were related to RLR through the analysis of miRNA high-throughput sequenci.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.30
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.30
Effect of neural stem cell transplantation combined with erythropoietin injection on axon regeneration in adult rats with transected spinal cord injury
Authors: Y. Zhao, Y. Zuo, X.L. Wang, H.J. Huo, J.M. Jiang, H.B. Yan and Y.L. Xiao
We investigated the effect of neural stem cells (NSC) and erythropoietin (EPO) on axon regeneration in adult rats with transected spinal cord injury, and provided an experimental basis for clinical treatment. Forty Wistar rats with T10-transected spinal cord injury were randomly divided into four groups of ten rats: a control group (group A), an NSC-trans.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.4
- DOI:
- 10.4238/2015.December.22.4
Expression patterns of the STAG gene in intact and regenerating planarians (Dugesia japonica)
Authors: Z.Q. Yuan, B.S. Zhao and J.Y. Zhang
We examined the spatial and temporal expression of the planarian Dugesia japonica STAG-related gene (DjStag), in both intact and regenerating planarians, by whole-mount in situ hybridization and relative quantitative real-time PCR. The first localized transcripts of DjStag were detected in the blastemas three days after amputa.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1042
- DOI:
- 10.4238/vol10-1gmr1042