Rna
MicroRNAs function primarily in the pathogenesis of human anencephalyvia the mitogen-activated protein kinase signaling pathway
Authors: W.D. Zhang, X. Yu, X. Fu, S. Huang, S.J. Jin, Q. Ning and X.P. Luo
Anencephaly is one of the most serious forms of neural tube defects (NTDs), a group of congenital central nervous system (CNS) malformations. MicroRNAs (miRNAs) are involved in diverse biological processes via the post-transcriptional regulation of target mRNAs. Although miRNAs play important roles in the development of mammal.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.20.3
- DOI:
- 10.4238/2014.February.20.3
Paracoccidioides brasiliensis RNA biogenesis apparatus revealed by functional genome analysis
Authors: PatrÃ?Âcia Albuquerque, Alessandra J. Baptista, Lorena da Silveira Derengowsky, Luciano ProcÃ?³pio, AndrÃ?© Moraes Nicola, FabrÃ?Âcio B.M. Arraes, Diorge Paulo de Souza, Cynthia Maria Kyaw and Ildinete Silva-Pereira
The RNA biogenesis machinery of Paracoccidioides brasiliensis was assessed by comparative analyses of PbAESTs (P. brasiliensis assembled expressed sequence tags (ESTs)) with sequences from Saccharomyces cerevisiae MIPS database. PbAESTs related to almost all categories of S. cerevisiae RNA biogenesis were found. Two of the 12 .. Read More»
- Genet. Mol. Res. 4(2):
Characterization of microRNAs and their target genes associated with transcriptomic changes in gamma-irradiated Arabidopsis
Authors: J.H. Kim, Y.S. Go, J.K. Kim and B.Y. Chung
MicroRNAs (miRNAs) regulate gene expression in response to biotic and abiotic stress in plants. We investigated gamma-ray-responsive miRNAs in Arabidopsis wild-type and cmt3-11t mutant plants using miRNA microarray analysis. miRNA expression was differentiated between the wild-type and cmt3-11t mutants. miR164a, miR169d, miR169h, miR172b*, and miR403 were.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038386
- DOI:
- 10.4238/gmr.15038386
Functional polymorphisms in microRNAs and susceptibility to liver cancer: a meta-analysis and meta-regression
Authors: B.S. Wang, Z. Liu, W.X. Xu and S.L. Sun
MicroRNAs (miRNAs) are small non-coding RNA molecules that play a fundamental role in controlling a variety of biological functions. Emerging evidence has shown that common genetic polymorphisms in miRNAs may be associated with the development of liver cancer; however, several individually published studies showed inconclusive.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.22
- DOI:
- 10.4238/2014.July.24.22
Effect of karst rocky desertification on soil fungal communities in Southwest China
Authors: P.C. Wang, B.T. Mo, Y. Chen, Q.F. Zeng and L.B. Wang
Karst mountainous ecosystems are associated with karst rocky desertification (KRD), which can greatly impact soil structure and function. Despite the importance of soil microbes as a major factor maintaining ecosystem stability, we know little about the effect on soil fungal communities of KRD in karst regions. We investigated this relationship across a g.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038460
- DOI:
- 10.4238/gmr.15038460
Effect of heat stress on heat-shock protein (Hsp60) mRNA expression in rainbow trout Oncorhynchus mykiss
Authors: H.N. Shi, Z. Liu, J.P. Zhang, Y.J. Kang, J.F. Wang, J.Q. Huang and W.M. Wang
The enhanced expression of heat shock proteins (hsps) in organisms can be detected in response to many kinds of stressor. For fish, high temperature is an important stressor, and hsp expression is associated with differences in environmental temperature. In this study, rainbow trout (Oncorhynchus mykiss) that were accustomed to an aquatic temperature of 1.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.20
- DOI:
- 10.4238/2015.May.18.20
De novo assembly and characterization of skin transcriptome using RNAseq in sheep (Ovis aries)
Authors: Y.J. Yue, J.B. Liu, M. Yang, J.L. Han, T.T. Guo, J. Guo, R.L. Feng and B.H. Yang
Wool is produced via synthetic processes of wool follicles, which are embedded in the skin of sheep. The development of new-generation sequencing and RNA sequencing provides new approaches that may elucidate the molecular regulation mechanism of wool follicle development and facilitate enhanced selection for wool traits through gene-assisted selection or .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.13.16
- DOI:
- 10.4238/2015.February.13.16
Prevalence of hepatitis A viral RNA and antibodies among Chinese blood donors
Authors: P. Sun, N. Su, F.Z. Lin, L. Ma, H.J. Wang, X. Rong, Y.D. Dai4, J. Li, Z.W. Jian6, L.H. Tang, W. Xiao and C.Q. Li
Like other developing countries, China was reported to have a relatively high seroprevalence of anti-hepatitis A antibodies (anti-HAV). However, no studies have evaluated the prevalence of anti-HAV and HAV RNA among voluntary blood donors with or without elevated serum alanine transaminase (ALT) levels. Anti-HAV antibodies were detected using an enzyme-li.. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
Up-regulation of Id1 in peripheral blood of psoriatic patients
Authors: C. Ronpirin, M. Achariyakul, T. Tencomnao, J. Wongpiyabovorn and W. Chaicumpa
Although the precise causes of psoriasis are unclear, it is widely accepted that psoriasis is a disorder in which factors in the immune system, enzymes, and other biochemical substances that regulate skin cell division are impaired, leading to rapid proliferation of keratinocytes and incomplete keratinization. Expression of th.. Read More»
- Genet. Mol. Res. 9(4):
- vol9-4gmr963
- DOI:
- 10.4238/vol9-4gmr963
Screening of crucial long non-coding RNAs in oral epithelial dysplasia by serial analysis of gene expression
Authors: X. Han, Y.B. Wei, G. Tian, Z. Tang, J.Y. Gao and X.G. Xu
Oral epithelial dysplasia (OED) is a premalignant lesion of the oral mucosa. Considering the poor 5-year survival rate of oral cancer, further investigation is needed in order to determine the pathogenesis of OED. In the present study, serial analysis of gene expression (SAGE) data from patients with OED were compared to norma.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.2.6
- DOI:
- 10.4238/2015.October.2.6