Rna
Marker-Assisted elimination of drought-susceptible accessions in upland rice breeding
Authors: Ariadna Faria Vieira, Gabriel Feresin Pantali�£o, Fernanda Martins Abreu, Ricardo Dias Silveira, Ana Letycia Basso Garcia, Leandro Gomide Neves, Rosana Pereira Vianello, Adriano Pereira Castro, Claudio Brondani
Breeding for water-deficit tolerance is fundamental to guarantee the sustainability of upland rice production, mainly due to the possibility of an increased frequency of drought episodes due to climate change. This work aimed to identify single nucleotide polymorphism (SNP) markers, derived from RNA sequencing (RNA-Seq), genom.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039886
- DOI:
- 10.4238/gmr16039886
LC-MS based identification of secondary metabolites from marine antagonistic endophytic bacteria
Authors: Fehmida Bibi, Muhammad Imran Naseer, Muhammad Yasir, Ahmed Abdullah Khalaf Al-Ghamdi, Esam Ibrahim Azhar
Halophytes occupy coastal and sub-coastal area of marine environment. They potential candidates for search of novel and new bacterial flora that have immense potential to yield novel therapeutic agents. Six different endophytic bacteria have been isolated from pneumatophores and roots of three halophytes (Salsola imbricata, Av.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039857
- DOI:
- 10.4238/gmr16039857
Decrypting the microRNA signatures in gastric cancer using high-throughput miRNA array coupled with systems biological approaches for precision medicine
Authors: Fehmida Bibi, Peter Natesan Pushparaj, Muhammad I. Naseer, Muhammad yasir, Esam I. Azhar
MicroRNAs (miRNAs) are non-coding small RNA molecules that regulate the differential expression of genes. The expression of miRNAs is dysregulated in various types of cancers, including Gastric Cancer (GC), and has both prognostic and diagnostic potential. To interpret the role of miRNA expression in GC, we evaluated the expre.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039845
- DOI:
- 10.4238/gmr16039845
Association between polymorphisms in TLR4 gene targeted by microRNA-140 and cervical precancerous lesion in south Chinese women: a case control study
Authors: Chuican Huang , Zhongyi Li , Xingming Zhong, Yao Wang, Xingguang Ye, Lipeng Jing, Shiqi Huang, Qian Yin , Zhulin Miao, Zixing Zhou, Yang Liu, Xiaohong Ye, Yajing Han, Meiling Ou, Di Xiao , Congcong Guo, Chengli Zeng, Guang Yang, Chunxia Jing, Xiangcai Wei
Toll-like receptor 4 (TLR4), one of the key immune system effectors, plays a main role in immune recognition of cervical cancer. Micro-RNAs are involved in regulation of multiple important genes in the progression of cervical cancer. A case-control study of 592 people was conducted from Yun’an County, Yunfu City, Guangdo.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039831
- DOI:
- 10.4238/gmr16039831
BmICE-2 interference vector construction and its silencing effect in the BmN-SWU1 cells
Authors: Hua-Shan Yi and Xianping Ma
Investigate the function of BmICE-2 gene in silkworm cells by constructing a BmICE-2 interference vector and analysing its interference effect. Online RNAi design software was used to predict the interference target sequence of Bmice-2. An optimized sequence was selected and inserted into the backbone of interference microRNA... Read More»
- Genet. Mol. Res. 16(4):
- gmr16039819
- DOI:
- 10.4238/gmr16039819
In vivo antimutagenic activity of the medicinal plants Pfaffia glomerata (Brazilian ginseng) and Ginkgo biloba
Authors: I.V. Almeida, E. D�¼sman, G.I. Mattge, F. Toledo, A.F. Reusing and V.E.P. Vicentini
Complementary and alternative therapies, including the use of medicinal plants, have become almost standard among the world’s population. Pfaffia glomerata (PG), popularly known as Brazilian ginseng, is widely used as a restorer of vital functions, increasing mental balance, and is used for the treatment of diabetes and .. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039785
- DOI:
- 10.4238/gmr16039785
Chemotherapeutical effects of the herbal medicine Uncaria tomentosa (Willd.) DC.
Authors: I.V. Almeida, L.C. Soares, F.T. Lucio, L.B. Cantagalli, A.F. Reusing and V.E.P. Vicentini
The use of medicinal plants dates back to the beginning of humanity, and today their application as complementary therapy has been widely disseminated as an alternative to conventional therapy. The medicinal plant named Uncaria tomentosa (Willd.) DC. (known as cat’s claw) is a common woody vine of the Amazon forest that .. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039782
- DOI:
- 10.4238/gmr16039782
Anthropization as a determinant factor in the genetic structure of Copernicia prunifera (Arecaceae)
Authors: L.G. Pinheiro, K.P.T. Chagas, A.S.M. Freire, M.C. Ferreira,C.G. Fajardo and F.A. Vieira
This study uses ISSR molecular markers to characterize the demographic pattern, and spatial genetic structure (SGS) at different life stages of development (cohorts) in a natural population of Copernicia prunifera in the Rio Grande do Norte State, Brazil. All individuals were sampled and georeferenced in a 0.55-ha plot. The de.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039768
- DOI:
- 10.4238/gmr16039768
Mating system and intrapopulational genetic diversity of Copernicia prunifera (Arecaceae): a native palm from Brazilian semiarid
Authors: R.A.R. Silva, C.G. Fajardo and F.A. Vieira
The aim of this study was to investigate the mating system and genetic diversity of the palm Copernicia prunifera using inter-simple sequence repeat markers. We found that the C. prunifera has multiple inflorescences with hermaphroditic flowers and pollen viability of 62%. Outcrossing rates at the population level (N = 267) pr.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039764
- DOI:
- 10.4238/gmr16039764
Inexpensive metagenomic DNA extraction protocol with high quality from marine sediments contaminated by petroleum hydrocarbons
Authors: I. GarcÃ?Âa-Bautista, T. Toledano-Thompson, E. DantÃ?¡n-GonzÃ?¡lez, J. GonzÃ?¡lez-Montilla and R. Valdez-Ojeda
Marine environments are a reservoir of relevant information on dangerous contaminants such as hydrocarbons, as well as microbial communities with probable degradation skills. However, to access microbial diversity, it is necessary to obtain high-quality DNA. An inexpensive, reliable, and effective metagenomic DNA (mgDNA) extra.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039743
- DOI:
- 10.4238/gmr16039743