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Rna

Human Genetics   Research Article

Genetic variations in microRNA genes and susceptibility to hepatocellular carcinoma

Authors: D. Li, J.J. Peng, Y. Tan, T. Chen, D. Wei, M. Du and T. Zhang

We conducted a hospital-based case-control study to investigate the effect of the miR-146aG>C and miR-499A>G polymorphisms on the risk of hepatocellular carcinoma (HCC) in a Chinese population. This study was 1:1 matched case-control study consisting of 184 HCC patients and 184 control subjects. miR-146aG>C and miR-499A>G polymorphisms were ge.. Read More»

Genet. Mol. Res. 14(1):
2015.March.20.2
DOI:
10.4238/2015.March.20.2
Animal Genetics   Research Article

RNA interference of leptin receptor in chicken adipocytes

Authors: A.X. Huang, J.J. Li, Y. Tian, J.D. Shen, Z.R. Tao, G.Q. Li, L.Z. Lu, Y. Fu and T.X. Wu

In this study, chicken adipocytes were cultured to evaluate RNA interference by the leptin receptor gene. A small interfering RNA of the leptin receptor gene was synthesized, with a suppression rate of 60% being generated (P peroxisome proliferator-activated receptor γ, fatty acid synthase, .. Read More»

Genet. Mol. Res. 13(3):
2014.August.7.5
DOI:
10.4238/2014.August.7.5
Medical Genetics   Research Article

Reason and treatment of failure of proximal femoral nail antirotation internal fixation for femoral intertrochanteric fractures of senile patients

Authors: J.J. Liu, L.C. Shan, B.Y. Deng, J.G. Wang, W. Zhu and Z.D. Cai

The cause of postoperative failure after the treatment of femoral intertrochanteric fracture with proximal femoral nail antirotation (PFNA) was analyzed, and the reoperative methods were examined. Nine failures of 308 femoral intertrochanteric fracture patients with PFNA were treated with femoral prosthesis total hip replaceme.. Read More»

Genet. Mol. Res. 13(3):
2014.August.7.10
DOI:
10.4238/2014.August.7.10
Plant Genetics   Research Article

Temporal genetic differentiation in cultured and natural beds of the brown mussel Perna perna (Mytilidae)

Authors: Appio KT and Weber LI

Perna perna is the most important cultivated mussel of Santa Catarina, Brazil, sustaining an important economic input for many local families. Natural stocks of P. perna are depleted by the extraction of adults and seeds for consumption and culture. The aim of the present study was to use the microsatellite locus pms-2 to stud.. Read More»

Genet. Mol. Res. 6(1):
Human Genetics   Research Article

Low metallothionein 1M expression association with poor hepatocellular carcinoma prognosis after curative resection

Authors: J. Ding and S.C. Lu

According to the typical clinical characteristics of hepatocellular carcinoma (HCC), recurrence and prognosis can differ dramatically between patients. Using RNA sequencing, we identified differential expression of the gene metallothionein 1M (MT1M) by comparing early-recurrence HCC (N = 11), no-recurrence HCC (N = 10), and no.. Read More»

Genet. Mol. Res. 15(4):
gmr.15048735
DOI:
10.4238/gmr.15048735
Animal Genetics   Research Article

Effect of lentivirus-mediated RNA interference of APC-Cdh1 expression on spinal cord injury in rats..

Authors: Y.-H. Qi, W.-L. Yao, C.-H. Zhang and Y.-Q. Guo

This study investigated cadherin-1 (Cdh1) expression in the sensorimotor cortex of rats after spinal cord injury (SCI). The repairing effect of Cdh1 was evaluated by silencing its expression with lentivirus-mediated RNAi. Twenty male Sprague-Dawley (SD) rats were randomly divided into a normal group and an operation group. Rat.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.28.9
DOI:
http://dx.doi.org/10.4238/2014.February.28.9
Animal Genetics   Research Article

Effect of lentivirus-mediated RNA interference of APC-Cdh1 expression on spinal cord injury in rats.

Authors: Y.-H. Qi, W.-L. Yao, C.-H. Zhang and Y.-Q. Guo

This study investigated cadherin-1 (Cdh1) expression in the sensorimotor cortex of rats after spinal cord injury (SCI). The repairing effect of Cdh1 was evaluated by silencing its expression with lentivirus-mediated RNAi. Twenty male Sprague-Dawley (SD) rats were randomly divided into a normal group and an operation group. Rat.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.28.9
DOI:
http://dx.doi.org/10.4238/2014.February.28.9
Human Genetics   Research Article

Effect of lentivirus-mediated RNA interference of APC-Cdh1 expression on spinal cord injury in rats

Authors: Y.-H. Qi, W.-L. Yao, C.-H. Zhang and Y.-Q. Guo

This study investigated cadherin-1 (Cdh1) expression in the sensorimotor cortex of rats after spinal cord injury (SCI). The repairing effect of Cdh1 was evaluated by silencing its expression with lentivirus-mediated RNAi. Twenty male Sprague-Dawley (SD) rats were randomly divided into a normal group and an operation group. Rat.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.28.9
DOI:
http://dx.doi.org/10.4238/2014.February.28.9
Animal Genetics   Original Articles

A rapid protocol for purification of total RNA for tissues collected from pigs at a slaughterhouse

Authors: V. M�©ndez, E. Avelar, A. Morales, M. Cervantes, A. Araiza and D. Gonz�¡lez

Since RNA extraction is a crucial step in many molecular techniques, the protocols for sample collection and RNA purification need to be adapted to optimize their performance when samples are collected from animals at commercial facilities. Here we provide an RNA purification protocol for animal tissues collected from slaughte.. Read More»

Genet. Mol. Res. 10(4):
2011.December.22.3
DOI:
10.4238/2011.December.22.3
Medical Genetics   Research Article

Molecular variation of Sporisorium scitamineum in Mainland China revealed by internal transcribed spacers

Authors: Y.Y. Zhang, N. Huang, X.H. Xiao, L. Huang, F. Liu, W.H. Su and Y.X. Que

Sugarcane smut caused by the fungus Sporisorium scitamineum is a worldwide disease and also one of the most prevalent diseases in sugarcane production in mainland China. To study molecular variation in S. scitamineum, 23 S. scitamineum isolates from the 6 primary sugarcane production areas in mainland, China (Guangxi, Yunnan, Guangdong, Hainan, Fujian, an.. Read More»

Genet. Mol. Res. 14(3):
2015.July.14.15
DOI:
10.4238/2015.July.14.15