Rna
Reduced miRNA-218 expression in pancreatic cancer patients as a predictor of poor prognosis
Authors: B.-S. Li, H. Liu and W.-L. Yang
microRNA-218 (miR-218) is a vertebrate-specific miRNA that plays a crucial role in tumorigenesis and tumor progression. This study analyzed the miR-218 expression level and clinical significance in pancreatic cancer. One hundred and seven pairs of pancreatic cancer and adjacent normal tissues were analyzed by quantitative reverse-transcriptase polymerase .. Read More»
- Genet. Mol. Res. 14(4):
- 2015
- DOI:
- 10.4238/2015
A C-type lectin fold gene from Japanese scallop Mizuhopecten yessoensis, involved with immunity and metamorphosis
Authors: X.B. Bao, C.B. He, C.D. Fu, B. Wang, X.M. Zhao, X.G. Gao andW.D. Liu
C-type lectins are a superfamily of Ca2+-dependent carbohydrate-recognition proteins that are well known for their participation in pathogen recognition and clearance. In this study, a putative C-type lectin fold (MyCLF) gene was identified from the Japanese scallop Mizuhopecten yessoensis. The full-length of MyCLF was 645 bp, encoding a polypeptide of 16.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.27.11
- DOI:
- 10.4238/2015.March.27.11
Comparison of different models to estimate genetic parameters for carcass traits in a commercial broiler line
Authors: J.L.B.M. Grosso, J.C.C. Balieiro, J.P. Eler, J.B.S. Ferraz, E.C. Mattos and T. Michelan Filho
The effect of genetic and non-genetic factors for carcass, breast meat and leg weights, and yields of a commercial broiler line were investigated using the restricted maximum likelihood method, considering four different animal models, including or excluding maternal genetic effect with covariance between direct and maternal g.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr773
- DOI:
- 10.4238/vol9-2gmr773
Molecular cloning, characterization, and expression of vacuolar-type-H+-ATPase B1 (VHAB1) gene in the gill of Anguilla marmorata
Authors: L. Li, Y.H. Jia, P. Li, S.W. Yin, G.S. Zhang, X.L. Wang, Y.Y. Wang and X.J. Wang
We explored the molecular mechanism of the regulation of vacuolar-type-H+-ATPase B1 (VHAB1) in elvers in the response to salinity. The full-length cDNA of VHAB1 in Anguilla marmorata (designated as AmVHAB1), which was 1741 base pairs (bp) in length, was found to encompass a 1512-bp open reading frame encoding a polypeptide with 503 amino acids (55.9 kDa),.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.17.9
- DOI:
- 10.4238/2015.July.17.9
Detection of genetic polymorphism among and within Echinococcus granulosus strains by heteroduplex analysis of a microsatellite from the U1 snRNA genes
Authors: P.A. Roratto, M.L. Bartholomei-Santos, A.M. Gutierrez, L. Kamenetzky, M.C. Rosenzvit and A. Zaha
Polymerase chain reaction of a pentanucleotide microsatellite in the U1 snRNA gene complex generated a multiple band pattern due to the priming of paralogous sequences. Denaturation and slow renaturation of polymerase chain reaction products allow the formation of heteroduplex DNA that can be detected by its differential mobil.. Read More»
- Genet. Mol. Res. 5(3):
Gynophore miRNA analysis at different developmental stages in Arachis duranensis
Authors: Y. Shen, Y.H. Liu, X.J. Zhang, Q. Sha and Z.D. Chen
Peanut is one of the most important oilseed crops in the world that provides a significant amount of lipids and protein for many people. The gynophore plays an important role in gynophore development after fertilization of the peanut ovule. MicroRNAs (miRNAs) play an important role in numerous developmental and physiological p.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048691
- DOI:
- 10.4238/gmr15048691
Inclusion of cytoplasmic lineage effect and direct-maternal genetic covariance for genetic evaluation of growth traits in Nellore cattle
Authors: L. Grigoletto, E.C. Mattos, M.H.A. Santana, F. Baldi, J.P. Eler and J.B.S. Ferraz
We evaluated the impact of cytoplasmic lineage effects (Lc) for growth traits on genetic evaluation, including the genetic covariance between direct and maternal effects (sam). Pedigree data from 496,190 Nellore animals and observations on birth weight (BW, N = 243,391), weaning weight (WW, N = 431,681), and post-weaning weight gain adjusted to 345 days (.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038812
- DOI:
- 10.4238/gmr.15038812
Molecular cloning and expression analysis of a matrix Gla protein gene in the spinyhead croaker, Collichthys lucidus
Authors: W. Song, M.D. Zhao, K.J. Jiang, F.Y. Zhang, M. Zhao, Y.Y. Meng and L.B. Ma
The matrix Gla (gamma-carboxyglutamic acid-rich) protein (MGP), a vitamin K-dependent and Gla-containing protein, is a calcification inhibitor that mainly functions in tissue calcification and mineralization. In this study, we obtained the complete cDNA sequence of MGP from the spinyhead croaker (Collichthys lucidus), which we.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049028
- DOI:
- 10.4238/gmr15049028
Genetic characterization of Brazilian strains of Aspergillus flavus using DNA markers
Authors: P.P. Batista, J.F. Santos, N.T. Oliveira, A.P.D. Pires, C.M.S. Motta and E.A. Luna-Alves Lima
The Aspergillus genus belongs to a filamentous fungal group characterized by wide dispersion in the environment. Some species are associated with diseases, especially in immunocompromised patients, while others are of economical importance due to aflatoxin production or biotechnological applications. Its species identification.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3gmr422
- DOI:
- 10.4238/vol7-3gmr422
Mutation in intron 5 of GTP cyclohydrolase 1 gene causes dopa-responsive dystonia (Segawa syndrome) in a Brazilian family
Authors: C.P. Souza, E.R. Valadares, A.L.C. Trindade, V.L. Rocha, L.R. Oliveira and A.L.B. Godard
Dopa-responsive dystonia (DRD), also known as Segawa syndrome or hereditary progressive dystonia with diurnal fluctuation, is clinically characterized by the occurrence of simultaneous or late Parkinsonism and by an excellent response to treatment with low doses of L-dopa. Diagnosis of DRD is essentially clinical. It is based .. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3gmr467
- DOI:
- 10.4238/vol7-3gmr467