Rna
MicroRNA variants and colorectal cancer risk: a meta-analysis
Authors: X.M. Pan, X. Xiao, H.J. Qin, Z. Zhang, Z.H. Li, L.B. Gao and J. Jia
Colorectal cancer (CRC) is a multi-factorial disease, and genetic background may contribute to its etiology. Single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) may be used as specific markers of predisposition for CRC diagnosis and preventionIn this review, we summarize and discuss recent publications evaluating the .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038478
- DOI:
- 10.4238/gmr.15038478
Genetic diversity and population structure of Fenneropenaeus penicillatus determined by mitochondrial DNA analyses
Authors: Y.Y. Cao and Z.B. Li
Fenneropenaeus penicillatus is a widely distributed economically and ecologically important shrimp species, which is endangered in China. Sequence analysis of 16s rRNA and control region (CR) fragments from mitochondrial DNA was conducted to obtain information on genetic diversity and population structure. Individuals from 12 .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038503
- DOI:
- 10.4238/gmr.15038503
Inactivation of Rab23 inhibits the invasion and motility of pancreatic duct adenocarcinoma
Authors: Z.Z. Cai, L.B. Xu, J.L. Cai, J.S. Wang, B. Zhou and H. Hu
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a poor prognosis and high mortality rate. In this study, we investigated the expression of Rab23 in non-tumor pancreatic tissues and PDACs via immunohistochemistry. Rab23 was found in 39 of 58 (67.2%) and in 11 of 30 (36.7%) of the PDAC and non-tumor pancreatic tissue samples (P = 0.007.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.31
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.31
Identification and abundance of miRNA in chicken hypothalamus tissue determined by Solexa sequencing
Authors: G.R. Sun, M. Li, G.X. Li, Y.D. Tian, R.L. Han and X.T. Kang
We used Solexa sequencing technology to identify and determine the abundance of miRNAs and compared the characteristics and expression patterns of miRNA of 1-day-old and 36-week-old chicken hypothalamuses. We obtained 17,825,753 and 10,928,745 high-quality reads from 36-week-old and 1-day-old chickens, respectively. Three hund.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.2.2
- DOI:
- 10.4238/2012.October.2.2
Abnormal male meiosis explains pollen sterility in the polyploid medicinal plant Pinellia ternata (Araceae)
Authors: Y. Liu, R.-K. Hui, R.-N. Deng, J.-J. Wang, M. Wang and Z.-Y. Li
Pinellia ternata is an important traditional Chinese medicinal plant. Its different populations in China have various ploidy levels, based on x = 13, as well as extensive aneuploid series. The microsporogenesis process was observed in specimens from three populations from three regions of Hubei Province; they were characterize.. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.January.17.1
- DOI:
- http://dx.doi.org/10.4238/2012.January.17.1
Involvement of the mitfa gene in the development of pigment cell in Japanese ornamental (Koi) carp (Cyprinus carpio L.)
Authors: J.H. Liu, S. Wen, C. Luo, Y.Q. Zhang, M. Tao, D.W. Wang,S.M. Deng and Y.M. Xiao
A colored phenotype is an important feature of ornamental fish. In mammals, microphthalmia-associated transcription factor (MITF) was found to regulate the development of melanocytes. In this study, the mitfa cDNA was first cloned from the Japanese ornamental (Koi) carp (Cyprinus carpio L.), an important ornamental freshwater fish. The full-length cDNA of.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.31.7
- DOI:
- http://dx.doi.org/10.4238/2015.March.31.7
Identification of conserved microRNAs and their target genes in Nile tilapia (Oreochromis niloticus) by bioinformatic analysis
Authors: X.H. Li, J.S. Wu, L.H. Tang and D. Hu
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in posttranscriptional regulation of target genes. miRNAs are involved in multiple biological processes by degrading targeted mRNAs or repressing mRNA translation in various organisms. Their conserved nature in various organisms makes them a good source of new miRNA discovery usin.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.31.8
- DOI:
- http://dx.doi.org/10.4238/2015.March.31.8
Evidence for the main foot protein gene in Perna perna (Mollusca, Mytilidae)
Authors: C. Clezar, L.I. Weber, g.S. Malaquias and p.O. Silva
Here, we investigated the gene that encodes the main protein component of the byssus in Perna perna (Ppfp) using a consensus fluorescent probe for the Mytilus group and by polymerase chain reaction amplification using specific and random primers. A 524-bp fragment resulting from polymerase chain reaction amplification was foun.. Read More»
- Genet. Mol. Res. 7(2):
Novel representation of RNA secondary structure used to improve prediction algorithms
Authors: Q. Zou, C. Lin, X.-Y. Liu, Y.-P. Han, W.-B. Li and M.-Z. Guo
We propose a novel representation of RNA secondary structure for a quick comparison of different structures. Secondary structure was viewed as a set of stems and each stem was represented by two values according to its position. Using this representation, we improved the comparative sequence analysis method results and the min.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1181
- DOI:
- 10.4238/vol10-3gmr1181
Molecular characterization of microduplication 22q11.2 in a girl with hypernasal speech
Authors: Y. Soysal, J. Vermeesch, N.A. Davani, N. ��ensoy, K. Hekimler and N. �°mirzal�±o��lu
We present a 12-year-old girl with karyotype 46,XX. A comparative genomic hybridization array revealed a 3.172-Mb microduplication on 22q11.2. This chromosome 22q11.2 region microduplication has been described in patients with variable phenotypes; a large majority of them have identical 3-Mb duplications. The girl presented mi.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1339
- DOI:
- 10.4238/vol10-3gmr1339