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Bioinformatics   Research Article

Characterization of glucose-tolerant �²-glucosidases used in biofuel production under the bioinformatics perspective: a systematic review

Authors: D.C.B. Mariano, C. Leite, L.H.S. Santos, L.F. Marins, K.S. Machado, A.V. Werhli, L.H.F. Lima and R.C. de Melo-Minardi

β-glucosidases are enzymes that catalyze the hydrolysis of oligosaccharides and disaccharides, such as cellobiose. These enzymes play a key role in cellulose degrading, such as alleviating product inhibition of cellulases. Consequently, they have been considered essential for the biofuel industry. However, the majority of.. Read More»

Genet. Mol. Res. 16(3):
gmr16039740
DOI:
10.4238/gmr16039740
Plant Genetics   Research Article

Diallel and prediction (REML/BLUP) for yield components in intervarietal maize hybrids

Authors: I.R. Carvalho, A.J. de Pelegrin, V.J. Szareski, M. Ferrari, T.C. da Rosa, T.S. Martins, N.L. dos Santos, M. Nardino, V.Q. de Souza, A.C. de Oliveira and L.C. da Maia

Genetic improvement is essential to achieve increments in maize (Zea mays L.) grain yield components. It may be obtained through crosses, which enable to exploit the effects of intervarietal heterosis, allelic complementarity, as well as gene actions and effects. This study estimated the components of variance and genetic para.. Read More»

Genet. Mol. Res. 16(3):
gmr16039734
DOI:
10.4238/gmr16039734
Human Genetics   Research Article

Mutational screening in the LDLR gene among patients presenting familial hypercholesterolemia in the Southeast of Brazil

Authors: G.A. Molfetta, D.L. Zanette, J.E. Santos and W.A. Silva Jr

Familial hypercholesterolemia (FH) is a dominant, autosomal disease characterized by high LDL levels in blood plasma, and is caused by a defect in the gene encoding the LDL receptor (LDLR). The clinical diagnosis is based on personal and familial history, physical examination findings, and measures of high LDL cholesterol conc.. Read More»

Genet. Mol. Res. 16(3):
gmr16039226
DOI:
10.4238/gmr16039226
Human Genetics   Research Article

MiR-200c inhibits metastasis of breast tumor via the downregulation of Foxf2

Authors: T. Zhang, J.G. Wan, J.B. Liu and M. Deng

The forkhead box F2 (Foxf2) gene suppresses epithelial-mesenchymal transition via the modulation of transcription of zinc finger E-box-binding homeobox 1 (Zeb1) and epithelial (E)-cadherin, thereby inhibiting tumor metastasis. Additionally, the specific binding of microRNA (miR)-200c to Foxf2 mRNA impedes metastatic pulmonary .. Read More»

Genet. Mol. Res. 16(3):
gmr16038971
DOI:
10.4238/gmr16038971
Human Genetics   Research Article

Assessment of genetic diversity of a native population of Eplingiella fruticosa: a plant with therapeutic potential

Authors: D.C. Silva, L.E.C. Diniz, A.F. Blank, D.A.C. Nizio, J.A.O. Pinto, K.L.G. Pereira and M.F. Arrigoni-Blank

Eplingiella fruticosa (Salzm. ex Benth.) Harley & J.F.B. Pastore, ex Hyptis fruticosa Salzm. ex Benth. is an aromatic and medicinal plant of the family Lamiaceae, found mainly in regions with intense anthropic activity. Information on the genetic diversity of this species is scarce. However, it can be assessed using molecu.. Read More»

Genet. Mol. Res. 16(3):
gmr16039749
DOI:
10.4238/gmr16039749
Human Genetics   Research Article

Synergic effect of oral contraceptives, GSTP1 polymorphisms, and high-risk HPV infection in development of cervical lesions

Authors: B.S. Chagas, A.P.A.D. Gurgel, S.S.L. Paiva J�ºnior, R.C.P. Lima,M.N. Cordeiro, R.R. Moura, A.V.C. Coelho, K.C.G. Nascimento,J.C. Silva Neto, S. Crovella and A.C. Freitas

Human papillomavirus (HPV) infection is considered a risk factor for cervical cancer. Even if the high-risk HPV (HR-HPV) infection is necessary, environmental co-factors and genetic susceptibility also play an important role in cervical cancer development. In this study, a possible association of rs1695 GSTP1 polymorphisms, HR.. Read More»

Genet. Mol. Res. 16(3):
gmr16039742
DOI:
10.4238/gmr16039742
Plant Genetics   Research Article

Stability of annual biomass energy production of elephant grass (Pennisetum purpureum Schum.) genotypes in the Northern region of the Rio de Janeiro State, Brazil

Authors: M.S.B. Ara�ºjo, R.F. Daher, B.R.S. Menezes, G.A. Gravina, V.B. Silva, A.T. Amaral J�ºnior, E.V. Rodrigues, B.O. Almeida and N.J. Ponciano

The objectives of this study were to estimate the stability of dry biomass production of elephant grass genotypes under an annual harvest regime, in soil-climatic conditions of the Northern region of the Rio de Janeiro State, Brazil, and to compare methodologies for stability analyses of Yates and Cochran (YC), Plaisted and Pe.. Read More»

Genet. Mol. Res. 16(3):
gmr16039041
DOI:
10.4238/gmr16039041
Plant Genetics   Research Article

Genotypic gain with simultaneous selection of production, nutrition, and culinary traits in cowpea crosses and backcrosses using mixed models

Authors: D.G. Oliveira, M.M. Rocha, K.J. Damasceno-Silva, F.V. S�¡, L.R.L. Lima, and M.D.V. Resende

The aim of this study was to estimate the genotypic gain with simultaneous selection of production, nutrition, and culinary traits in cowpea crosses and backcrosses and to compare different selection indexes. Eleven cowpea populations were evaluated in a randomized complete block design with four replications. Fourteen traits .. Read More»

Genet. Mol. Res. 16(3):
gmr16039736
DOI:
10.4238/gmr16039736
Plant Genetics   Research Article

Evaluation of genotype x environment interactions in cotton using the method proposed by Eberhart and Russell and reaction norm models

Authors: R.S. Alves, P.E. Teodoro, F.C. Farias, F.J.C. Farias, L.P. Carvalho, J.I.S. Rodrigues, L.L. Bhering and M.D.V. Resende

Cotton produces one of the most important textile fibers of the world and has great relevance in the world economy. It is an economically important crop in Brazil, which is the world’s fifth largest producer. However, studies evaluating the genotype x environment (G x E) interactions in cotton are scarce in this country... Read More»

Genet. Mol. Res. 16(3):
gmr16039726
DOI:
10.4238/gmr16039726
Plant Genetics   Research Article

Correlation study of resistance components in the selection of Capsicum genotypes resistant to the fungus Colletotrichum gloeosporioides

Authors: A.C. Maracahipes, J.W.S. Correa, P.E. Teodoro, K.L. Ara�ºjo, M.A.A. Barelli and L.G. Neves

Anthracnose is among the major diseases of the Capsicum culture. It is caused by different species of the genus Colletotrichum, which may result in major damages to the cultivation of this genus. Studies aiming to search for cultivars resistant to diseases are essential to reduce financial and agricultural losses. The objectiv.. Read More»

Genet. Mol. Res. 16(3):
gmr16039720
DOI:
10.4238/gmr16039720