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Reproductive outcome of male carriers of chromosomal abnormalities: multidisciplinary approach for genetic counseling and its implications
Authors: K.M. Guo, B. Wu, H.B. Wang and R.H. Tian
Chromosomal abnormality is the most common genetic cause of infertility. Infertility, as a psychological problem, has received an increasing amount of attention. Psychological interventions have been shown to have beneficial effects on infertile patients with chromosomal abnormalities. The present study explored reproductive o.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048963
- DOI:
- 10.4238/gmr15048963
Characterization of the Toxoplasma gondii hsp60 gene sequences from different hosts and geographical locations
Authors: J. Lu, D.H. Zhou, J. Chen, N.Z. Zhang, R.A. Wang, Y.B. Weng and X.Q. Zhu
The intracellular protozoan Toxoplasma gondii is one of the most successful parasites, with the ability to invade all warm-blooded animals, including humans. T. gondii heat shock protein 60 (TgHSP60) plays an important role in intracellular survival and in the differentiation of the parasite, and is also recognized as being associated wi.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.29.13
- DOI:
- 10.4238/2014.August.29.13
Role of glutathione and other antioxidants in the inhibition of apoptosis and mesenchymal transition in rabbit lens epithelial cells
Authors: H.J. Wang, J. Zhu and G.Y. Zheng
This study aimed to discuss the effect and mechanism of glutathione (GSH) and catalase (CAT) on transforming growth factor beta (TGF-β)-induced lens epithelial cell (LEC) apoptosis and epithelial mesenchymal transition (EMT) to prevent and control cataracts. Healthy rabbits (4 weeks old) were randomly selected, and LECs f.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.1.1
- DOI:
- 10.4238/2014.September.1.1
Isolation and characterization of novel microsatellite markers from Siamese fighting fish (Betta splendens, Osphronemidae, Anabantoidei) and their transferability to related species, B. smaragdina and B. imbellis
Authors: V. Chailertrit, A. Swatdipong, S. Peyachoknagul, J. Salaenoi and K. Srikulnath
Ten novel microsatellite markers were developed and characterized from Siamese fighting fish (Betta splendens). Nine of ten markers were polymorphic, exhibiting an allelic number (NA) from 2 to 6 alleles per locus. The effective number of alleles (NE) ranged from 1.60 to 3.08 (average of 2.30). The observed (HO) and expected (.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.1
- DOI:
- 10.4238/2014.September.5.1
Cryopreservation of Schisandra chinensis (Turcz.) Baill callus and subsequent plant regeneration
Authors: D. Sun, Y.-F. Yu, H.-Y. Qin, P.-L. Xu, Y. Zhao, Y.-X. Liu, Z.-X. Wang, S.-T. Fan, Y.-M. Yang and J. Ai
Cryopreservation has been proven significance as a technique for promising the long-term conservation of plant germplasms. This study aimed to establish a cryopreservation protocol for calli of Schisandra chinensis (Turcz.) Baill, and to explore the effects of different process parameters on callus viability. Effects of desicc.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049342
- DOI:
- 10.4238/gmr15049342
Matrix metalloproteinase gene polymorphisms and susceptibility to systemic sclerosis
Authors: T.F. Rech, S.B.C. Moraes, M. Bredemeier, J. de Paoli, J.C.T. Brenol, R.M. Xavier, J.A.B. Chies and D. Simon
The major pathological hallmark of the systemic sclerosis (SSc) is skin and internal organ fibrosis, which results from normal tissue architecture alterations and extracellular matrix (ECM) protein deposition. ECM components are degraded by matrix metalloproteinases (MMP). Promoter region polymorphisms in MMP genes may influen.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049077
- DOI:
- 10.4238/gmr15049077
Genetic variations of 21 STR markers on chromosomes 13, 18, 21, X, and Y in the south Iranian population
Authors: J. Saberzadeh, M.R. Miri, M.B. Tabei, M. Dianatpour and M. Fardaei
Quantitative fluorescent polymerase chain reaction (QF-PCR), in recent years, has been accepted as a rapid, high throughput, and sensitive method for prenatal diagnosis of common chromosomal aneuploidies. Since short tandem repeats (STRs) are the cornerstone of QF-PCR technique, selection of the most polymorphic STR markers is.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049065
- DOI:
- 10.4238/gmr15049065
Genetic progress in oat associated with fungicide use in Rio Grande do Sul, Brazil
Authors: D.N. Follmann, A. Cargnelutti Filho, A.D. L�?ºcio, V.Q. de Souza, M. Caraffa and C.A. Wartha
The State of Rio Grande do Sul (RS) is the largest producer of oat in Brazil with the aid of consolidated breeding programs, which are constantly releasing new cultivars. The main objectives of this study were to: 1) evaluate the annual genetic progress in grain yield and hectoliter weight of the oat cultivars in RS, with and .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049390
- DOI:
- 10.4238/gmr15049390
Drosha, DGCR8, and Dicer mRNAs are downregulated in human cells infected with dengue virus 4 - Genet. Mol. Res. 15 (2): gmr.15027891 Drosha, Dicer, and TRBP mRNA are downregulated in Vero cells with the 3 UTR of Dengue virus
Authors: J.A. Castillo and S. Urcuqui-Inchima
A recent paper (Casseb et al., 2016) published in the journal Genetics and Molecular Research described the interesting concept that dengue virus (DENV)-4 infection, in the human cell line A-549, leads to the downregulation of expression of key components of microRNA (miRNA) biogenesis, such as Drosha, Dicer, and DGCR8. For th.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039050
- DOI:
- 10.4238/gmr.15039050
Genomic selection of seed weight based on low-density SCAR markers in soybean
Authors: Y.J. Shu, D.S. Yu, D. Wang, X. Bai, Y.M. Zhu and C.H. Guo
With the development of molecular marker technology, crop breeding has been accelerated by marker-assisted selection for the improvement of quantitative traits. However, due to the traits’ polygenic nature, traditional marker-assisted selection methods are ill-suited for identification of quantitative trait loci. Genomic selection (GS) was introduce.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.3.2
- DOI:
- 10.4238/2013.July.3.2