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Plant Genetics   Research Article

Bulk segregant analysis (BSA) for improving cold stress resistance in maize using SSR markers

Authors: M.Q.U. Farooqi, K.J. Sa, T.K. Hong and J.K. Lee

In this study, eight inbred maize lines with high or low tolerance to cold temperature were investigated using bulk segregant analysis (BSA). Genetic diversity and genetic relationships were investigated using 100 simple sequence repeat (SSR) markers linked to cold tolerance in maize. A total of 319 alleles were identified. Am.. Read More»

Genet. Mol. Res. 15(4):
gmr15049326
DOI:
10.4238/gmr15049326
Animal Genetics   Research Article

Effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition in experimental biliary atresia mouse models

Authors: J.Y. Wang, Z.H. Li, M. Ye, Q. Feng, Z.M. Chen, X.S. Ye, Z.G. Wu, B. Wang, L. Liu and J. Yao

Biliary atresia (BA) is a destructive bile duct disease occurring in newborn children within a few weeks after birth. In this study, the effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition (EMT) in experimental BA was explored by constructing BA mouse models via Rhesus rotavirus vaccine infection. miR-29c and.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037753
DOI:
10.4238/gmr.15037753
Plant Genetics   Research Article

Genomic variability of Pantoea ananatis in maize white spot lesions assessed by AFLP markers

Authors: A.M. Miller, J.E.F. Figueiredo, C.L. Chaves, E.A. Ruas, M.I. Balbi-Pe�±a, N.B. Colauto and L.D. Paccola-Meirelles

Measures to control maize white spot (MWS) caused by Pantoea ananatis are preferentially based on resistant cultivars. A lack of knowledge on the genetic variability of pathogens could interfere with the development and utilization of controlling strategies in this pathosystem. The main goals of this study were to investigate .. Read More»

Genet. Mol. Res. 15(4):
gmr15049452
DOI:
10.4238/gmr15049452
Plant Genetics   Research Article

Genetic variability affecting Exserohilum turcicum resistance in popcorn lines grown under high and low phosphorus conditions

Authors: A.T. Amaral Jr., R.M. Ribeiro, P.H.D. Santos, T.P.S. Poltronieri, J.M.S. Vivas, I.F.S. Gerhardt, B.M. Carvalho, C.S. Freitas and S.B. Miranda

Northern leaf blight (NLB), caused by Exserohilum turcicum, is one of the main foliar diseases that affect popcorn culture. Farmers use many control measures to minimize damage caused by this disease, among which, the use of cultivars with genetic resistance is the most effective and economical. The aim of this study was to in.. Read More»

Genet. Mol. Res. 15(4):
gmr15049399
DOI:
10.4238/gmr15049399
Cytogenomics   Research Article

Gene expression in the lignin biosynthesis pathway during soybean seed development

Authors: A. Baldoni, E.V.R. Von Pinho, J.S. Fernandes, V.M. Abreu and M.L.M. Carvalho

The study of gene expression in plants is fundamental, and understanding the molecular mechanisms involved in important biological processes, such as biochemical pathways or signaling that are used or manipulated in improvement programs, are key for the production of high-quality soybean seeds. Reports related to gene expression of lignin in seeds are sca.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.2
DOI:
10.4238/2013.February.28.2
Human Genetics   Research Article

Association between TXNRD1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a prospective study

Authors: G.Y. Ji, Y. Wang, S.Q. Wu, Q.Q. Liu, J.C. Wu, M.M. Zhang, A.J. Sandford and J.Q. He

Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is a serious adverse reaction to anti-tuberculosis (TB) treatment. Thioredoxin reductase 1 (TXNRD1), encoded by the TXNRD1 gene, is an important enzyme involved in oxidant challenge. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells aga.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038296
DOI:
10.4238/gmr.15038296
Microbial Genetics   Research Article

Segregation and genetic linkage analyses of river catfish, Mystus nemurus, based on microsatellite markers

Authors: B.P. Hoh, S.S. Siraj, S.G. Tan and K. Yusoff

The river catfish Mystus nemurus is an important fresh water species for aquaculture in Malaysia. We report the first genetic linkage map of M. nemurus based on segregation analysis and a linkage map using newly developed microsatellite markers of M. nemurus. A total of 70 of the newly developed polymorphic DNA microsatellite markers were analyzed on pedi.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.1
DOI:
10.4238/2013.February.28.1
Medical Genetics   Research Article

Effects of ginsenoside Rg1 on the senescence of vascular smooth muscle cells

Authors: S.G. Li, M.Z. Yan, D. Zhang, M. Ye and J.J. Deng

The development of age-related cardiovascular disease is associated with the senescence of vascular cells. This study aimed to investigate the effect of ginsenoside Rg1 on vascular smooth muscle cell (VSMC) senescence. Primary VSMCs were cultured and divided into control, D-galactose (D-gal), Rg1-L, and Rg1-H groups, which wer.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038409
DOI:
10.4238/gmr.15038409
Plant Genetics   Research Article

Proposal of a super trait for the optimum selection of popcorn progenies based on path analysis

Authors: A.T. do Amaral J�ºnior, A. dos Santos, I.F.S. Gerhardt, R.N.F. Kurosawa, N.F. Moreira, M.G. Pereira, G. de A. Gravina and F.H. de L. Silva

A challenge faced by popcorn breeding programs is the existence of a negative correlation between the two main traits, popping expansion and yield, which hinders simultaneous gains. The objective of this study was to investigate the use of a new variable or super trait, which favors the reliable selection of superior progenies.. Read More»

Genet. Mol. Res. 15(4):
gmr15049309
DOI:
10.4238/gmr15049309
Medical Genetics   Research Article

Characterization and comparison of EST-SSR and TRAP markers for genetic analysis of the Japanese persimmon Diospyros kaki

Authors: C. Luo, F. Zhang, Q.L. Zhang, D.Y. Guo and Z.R. Luo

We developed and characterized expressed sequence tags (ESTs)-simple sequence repeats (SSRs) and targeted region amplified polymorphism (TRAP) markers to examine genetic relationships in the persimmon genus Diospyros gene pool. In total, we characterized 14 EST-SSR primer pairs and 36 TRAP primer combinations, which were amplified across 20 germplasms of .. Read More»

Genet. Mol. Res. 12(3):
2013.January.9.3
DOI:
10.4238/2013.January.9.3