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Polymorphic microsatellite markers for the endangered fish, the slender shiner Pseudopungtungia tenuicorpa and cross-species amplification across five related species
Authors: K.S. Ki, S.J. Moo, S.H. Han2, K.Y. Kim and I.C. Bang
The slender shiner Pseudopungtungia tenuicorpa (Cypriniformes; Cyprinidae; Gobioninae) is an endangered freshwater fish species endemic to Korea. The current strategies for its conservation involve the study of population genetic characters and identification of management units. These strategies require suitable molecular mar.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038496
- DOI:
- 10.4238/gmr.15038496
Protective role of neuregulin-1 toward doxorubicin-induced myocardial toxicity
Authors: Y.Q. Liu, M. Yang, C.H. Duan, G.B. Su, J.H. Wang, Y.F. Liu and J. Zhang
The aim of this study was to investigate the role of the rat neuregulin-1 (NRG-1) protein in reducing doxorubicin (DOX)-induced myocardial toxicity and its underlying mechanism. The prokaryotic expression of the NRG-1 protein and the CCK8-determined activity of rat primary myocardial cells were evaluated under different DOX co.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.June.18.5
- DOI:
- 10.4238/2014.June.18.5
Study of the correlation between GH gene polymorphism and growth traits in sheep
Authors: J.L. Jia, L.P. Zhang, J.P. Wu, Z.J. Ha and W.W. Li
The growth hormone gene plays an important role in the physiological function of an organism. The current study aimed to investigate the correlation between polymorphisms in the 5êÂ?Â? regulatory region, exon 4, and 3êÂ?Â? untranslated region (UTR) of the sheep GH gene and sheep growth traits. The DNA from 510 adult sheep wa.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.5
- DOI:
- 10.4238/2014.September.5.5
Identification of genes involved in regulatory mechanism of pigments in broiler chickens
Authors: T.M. Tarique, S. Yang, Z. Mohsina, J. Qiu, Z. Yan, G. Chen and A. Chen
Chicken is an important model organism that unites the evolutionary gap between mammals and other vertebrates and provide major source of protein from meat and eggs for all over the world population. However, specific genes underlying the regulatory mechanism of broiler pigmentation have not yet been determined. In order to be.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.6
- DOI:
- 10.4238/2014.September.5.6
Protection from vascular endothelial dysfunction in acute glycemic load-induced primary hypertension by vitamin C and E
Authors: J.X. Xu, L. Su, L. Chen and J.X. Lin
This study aimed to investigate the influence of acute glycemic load on vascular endothelial function in patients with hypertension and to evaluate the protective effect of vitamins C and E during the acute glycemic phase. We randomly selected 39 hypertensive patients and 21 normal subjects and divided them into 3 groups: 75 g.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.9
- DOI:
- 10.4238/2014.September.5.9
IL-23 promotes osteoclastogenesis in osteoblast-osteoclast co-culture system
Authors: Y.K. Kang and M.C. Zhang
The aim of this study was to determine the effect of IL-23 on the activity and proliferation of osteoclasts (OC) in co-culture with osteoblasts (OB). OB and OC were individually separated from the skull and femoral bone of a SD rat. OB-OC co-culture with IL-23 added was designed as the experimental group, while the OB-OC co-cu.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.June.18.10
- DOI:
- 10.4238/2014.June.18.10
Torasemide reduces dilated cardiomyopathy, complication of arrhythmia, and progression to heart failure
Authors: L.N. Han, S.L. Guo, X.M. Lin, X.M. Shi, C.B. Zang, L.M. Yang and G.L. Ding
The aim of this study was to analyze the incidence and types of arrhythmia and their relationship with the severity and prognosis of chronic heart failure (CHF) in patients with dilated cardiomyopathy (DCM), and to investigate the therapeutic effect of torasemide versus furosemide on CHF and incidence of arrhythmia. DCM patien.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.11
- DOI:
- 10.4238/2014.September.5.11
Comparative analysis of soybean genotype resistance to Heterodera glycines and Meloidogyne species via resistance gene analogs
Authors: P.M.H. Vieira, F.A.S. Ar�ªdes, A. Ferreira and M.F.S. Ferreira
Nematodes are important pests of soybean throughout the world and cause high yield losses. As a control strategy, the identification of resistance genes is an important aim of breeding studies. Plants possess resistance genes (R), which are responsible for the recognition of pathogens and activation of the defense system. R ge.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038562
- DOI:
- 10.4238/gmr.15038562
Discovery of differentially expressed genes in cashmere goat (Capra hircus) hair follicles by RNA sequencing
Authors: X. Qiao, J.H. Wu,, R.B. W, R. Su, C. Li, Y.J. Zhang1, R.J. Wang, Y.H. Zhao, Y.X. Fan, W.G. Zhang and J.Q. Li
The mammalian hair follicle (HF) is a unique, highly regenerative organ with a distinct developmental cycle. Cashmere goatCapra hircus) HFs can be divided into two categories based on structure and development time: primary and secondary follicles. To identify differentially expressed genes (DEGs) in the primary and secondary .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038589
- DOI:
- 10.4238/gmr.15038589
Use of microsatellite markers in molecular analysis of segregating populations of papaya (Carica papaya L.) derived from backcrossing
Authors: F.O. Pinto, M.G. Pereira, L.N. Luz, D.L. Cardozo, H.C.C. Ramos and C.M.P. Macedo
Brazil is the world leader in papaya production. However, only a small number of cultivars are registered for commercial planting, mainly owing to delays in obtaining cultivars and the high costs of the field phase of breeding programs. These costs can be reduced when molecular tools are combined with conventional breeding methods. In the present study, w.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.8.6
- DOI:
- 10.4238/2013.July.8.6