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Expression and serological diagnosis of Mycobacterium tuberculosis CFP-10 and Rv2626c proteins
Authors: Z.Y. Zhu, D. Zhang, H.B. Wang, J.Z. Xiao, Y.F. Qiu, L. Yan, D. Chen, A.G. Liu and X. Yang
We constructed a Mycobacterium tuberculosis vector expressing CFP-10 and Rv2626c to examine the expression of these proteins in Escherichia coli as well as their immunoreactivity. The CFP-10 and Rv2626c genes were amplified from tuberculosis H37Rv genomic DNA using polymerase chain reaction. They were ligated.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.12.5
- DOI:
- 10.4238/2014.September.12.5
DNA barcoding and evolutionary relationships of the Phasianidae family in China
Authors: Z.H. Huang and D.H. Ke
A DNA barcode is a short sequence of standardized genomic region that is specific to a species. According to studies of bird species, the 694-bp sequence of the mitochondrial gene encoding cytochrome c oxidase 1 (COI) is extremely useful for species identification and phylogeny. In the present study, we analyzed the COI barcod.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.12.7
- DOI:
- 10.4238/2014.September.12.7
Expression of COX-2 and VEGF-C in cholangiocarcinomas at different clinical and pathological stages
Authors: Z. You, L. Bei, L.P. Cheng and N.S. Cheng
The aim of this study was to investigate the expression and clinical significance of cyclooxygenase 2 (COX-2) and vascular endothelial growth factor C (VEGF-C) in cholangiocarcinomas at different clinical and pathological stages. Eighty cholangiocarcinoma samples of patients treated with surgery between January 2012 and January 2014 were collected. Immuno.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.9
- DOI:
- 10.4238/2015.June.9.9
Diffuse large B-cell lymphoma in the primary bone marrow
Authors: Y. Hu, S.L. Chen, Z.X. Huang, W. Gao and N. An
This study aimed to improve understanding of the diagnosis, treatment, and prognosis of primary bone marrow (PBM) diffuse large B-cell lymphoma (DLBCL), a rare illness. We report a 56-year-old man with pancytopenia and hyperbilirubinemia but without lymphadenopathy, hepatomegaly, or splenomegaly. Bone marrow aspiration, flow cytometry, biopsy, and immunoh.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.10
- DOI:
- 10.4238/2015.June.9.10
Association between the FCGR2A gene H131R polymorphism and risk of Kawasaki disease: a meta-analysis
Authors: L. Lin, S.Y. Wang, S.B. Yang and F.C. Xiao
Several previous studies have investigated whether the FCGR2A gene H131R polymorphism confers an increased risk of Kawasaki disease (KD), but conflicting results have been reported. To further explore the association of this polymorphism with KD susceptibility, we performed an extensive search of relevant studies and conducted a meta-analysis to obtain a .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.9.12
- DOI:
- 10.4238/2015.June.9.12
Association of DNA repair gene polymorphisms with response to chemotherapy and prognosis of gastric cancer
Authors: Z.H. Chen, L. Wang and L.P. Luo
We investigated the correlation between the response to chemotherapy in patients and excision repair cross-complimentary group 1 gene (ERCC1) and xeroderma pigmentosum complementation group F gene (XPF) polymorphisms and the effect of these polymorphisms on the clinical outcome of gastric cancer. Samples from a total of 255 patients with.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.12.15
- DOI:
- 10.4238/2014.September.12.15
Cardioprotective effects mitochondrial ATP-sensitive potassium channel in exercise conditioning
Authors: F.-L. Peng, Y.-J. Guo, W.-B. Mo, S.-M. Xu and H.-P. Liao
We investigated the mitochondrial ATP-sensitive potassium channel [mito-K (ATP)] in exercise preconditioning of myocardial ischemia-reperfusion injury in rats. Eighty SD rats were randomly divided into high-, moderate-, low-intensity, and control groups. The exercise groups were divided into control and inhibited groups. The c.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.12.17
- DOI:
- 10.4238/2014.September.12.17
Meta-analysis of TAFI polymorphisms and risk of cardiovascular and cerebrovascular diseases
Authors: S.W. Wang, H.H. Zhang, C.Y. Dong and H.H. Sun
Cardiovascular and cerebrovascular diseases (CCVDs) are common and have high rates of morbidity, mortality, and recurrence. Thrombin-activatable fibrinolysis inhibitor (TAFI) is also known as carboxypeptidase B2 and is encoded by the CPB2 gene; CPB2 polymorphisms have been explored in a variety of studies, but their correlatio.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026718
- DOI:
- 10.4238/gmr.15026718
Prediction of genetic risk factors of atherosclerosis using various bioinformatic tools
Authors: H.X. Wang and Y.X. Zhao
The aim of this study was to identify potential markers of atherosclerosis development in familial hypercholesterolemia (FH) patients. GSE13985 microarray data, generated using blood samples from 5 FH patients and 5 matched controls, was downloaded from the Gene Expression Omnibus. Differentially expressed genes (DEGs) between.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027347
- DOI:
- 10.4238/gmr.15027347
Post-transcriptional silencing of the SGE1 gene induced by a dsRNA hairpin in Fusarium oxysporum f. sp cubense, the causal agent of Panama disease
Authors: J.S. Fernandes, P.C.S. Angelo, J.C. Cruz, J.M.M. Santos, N.R. Sousa and G.F. Silva
Fusarium oxysporum f. sp cubense (Foc), the causal agent of Panama disease, is responsible for economic losses in banana crops worldwide. The identification of genes that effectively act on pathogenicity and/or virulence may contribute to the development of different strategies for disease control and the production of resista.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027941
- DOI:
- 10.4238/gmr.15027941