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Association of -238G/A and -863C/A polymorphisms in the TNF-�± gene with chronic obstructive pulmonary disease based on a meta-analysis
Authors: K. Cui, X.Y. Ge and H.L. Ma
Chronic obstructive pulmonary disease (COPD) is a chronic systemic inflammatory disease; increasing evidence indicates that the TNF-α polymorphism is associated with progression of this disease. Few studies have focused upon association between TNF-α -238G/A or -863C/A polymorphism and COPD risk. Reported associations have been controversial b.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.10
- DOI:
- 10.4238/2013.October.24.10
Genetic diversity of the Chinese traditional herb Blumea balsamifera (Asteraceae) based on AFLP markers
Authors: Y.X. Pang, W.Q. Wang, Y.B. Zhang, Y. Yuan, J.B. Yu, M. Zhu and Y.Y. Chen
Blumea balsamifera is a commercially important medicinal herb in China and other parts of Asia. It is used to produce borneol. This plant grows in the wild, but resources have diminished greatly in recent years. We examined the genetic diversity of this species to help develop conservation strategies; 35 plants from five provi.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.1
- DOI:
- 10.4238/2014.April.14.1
A multi-farm assessment of Greek black pig genetic diversity using microsatellite molecular markers
Authors: S. Michailidou, A. Kalivas, I. Ganopoulos, E. Stea, G. Michailidis, A. Tsaftaris and A. Argiriou
Local breeds are important for the maintenance of genetic diversity and future food security. Nowadays, the worldwide distribution of pigs is dominated by a few breeds, tending towards a severe loss of pig biodiversity. Thus, it is critical to maintain distinct populations of pig breeds. The Greek black pig, a breed raised loc.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.4
- DOI:
- 10.4238/2014.April.14.4
In vivo mechanism study of NGAL in rat renal ischemia-reperfusion injury
Authors: X.J. Zang1, S.X. An2, Z. Feng1, Y.P. Xia1, Y. Song and Q. Yu
This study aimed to determine the protective effect and mechanism of neutrophil gelatinase-associated lipocalin (NGAL) in rat kidney on ischemia/reperfusion injury (I/R). The rat I/R model was set up by cutting one kidney and clamping the contralateral renal pedicle for 45 min. Male SD rats were randomly divided into sham-oper.. Read More»
- Genet. Mol. Res. 13(4):
Multidrug-resistant genes of aminoglycoside-modifying enzymes and 16S rRNA methylases in Acinetobacter baumannii strains
Authors: J.-T. Wen, Y. Zhou, L. Yang and Y. Xu
We examined the distribution of genes of aminoglycoside-modifying enzymes and 16S rRNA methylases in multidrug-resistant Acinetobacter baumannii to explore the association of these genes with drug resistance. Strains isolated from clinical specimens were screened using an automatic microbial identification system, and 9 aminog.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.9
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.9
Inbreeding effects in Solanum lycocarpum A. St.-Hil populations, an endangered species of the Brazilian Cerrado
Authors: T.M. Moura, M.V.B.M. Siqueira, G.C.X. Oliveira
The inbreeding effective population size is an estimate of inbreeding and genetic drift in populations. It is an important tool for conservation genetics because it represents the number of individuals that are effectively contributing alleles to the subsequent generations. Several studies have been published in the last decad.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.10
- DOI:
- 10.4238/2013.November.26.10
Expression and enzymatic activity of phenylalanine ammonia-lyase and p-coumarate 3-hydroxylase in mango (Mangifera indica �Ataulfo�) during ripening
Authors: H. Palafox-Carlos, C.A. Contreras-Vergara, A. Muhlia-Almaz�¡n, M.A. Islas-Osuna and G.A. Gonz�¡lez-Aguilar
Phenylalanine ammonia lyase (PAL) and p-coumarate 3-hydroxylase (C3H) are key enzymes in the phenylpropanoid pathway. The relative expression of PAL and C3H was evaluated in mango fruit cultivar ‘Ataulfo’ in four ripening stages (RS1, RS2, RS3, and RS4) by quantitative polymerase chain reaction. In addition, enzyme.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.10
A preliminary mutation analysis of phenylketonuria in southwest Iran
Authors: N. Ajami1*, S.R. Kazeminezhad1*, A.M. Foroughmand1, M. Hasanpour1 and M. Aminzadeh2
Phenylketonuria (PKU) is a heterogeneous and autosomal recessive metabolic disorder that is mainly caused by mutations in the hepatic phenylalanine hydroxylase (PAH) gene. This study was designed to identify PAH mutations within exons 6, 7, and 10-12 in PKU patients from southwest Iran. Forty Iranian patients with clinical and biochemically confirmed PKU .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.7
- DOI:
- 10.4238/2013.October.24.7
Molecular and biochemical characterization of the effects of insecticidal toxin from meloidae beetles on Helicoverpa armigera (Hub.) (Lepidoptera: Noctuidae)
Authors: R.A. Khan1, M. Rashid1, D. Wang2 and Y.L. Zhang1
The molecular and biochemical effects of an insecticidal toxin extracted from Meloidae beetles were investigated on Helicoverpa armigera. The toxin was identified as cantharidin, a well-known natural compound produced by beetles of family Meloidae and Oedemeridae. Furthermore, the effect of the toxin on the metabolic enzymes alkaline phosphatase (ALP) and.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.5
- DOI:
- 10.4238/2013.October.10.5
Expression of heat shock protein 90 alpha (Hsp90�±) in primary neonatal rat myocardial cells exposed to various periods of heat stress in vitro
Authors: A. Islam, B. Rehana, M. Zhang, Z.J. Liu, S. Tang, J. Hartung and E.D. Bao
The objective of this study was to investigate the mechanism of heat shock protein 90 alpha (Hsp90α) protection against heart damage resulting from heat stress by detecting Hsp90α mRNA, Hsp90α protein, protein localization, and cell damage in primary myocardial cells of neonatal rats in response to heat stres.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.9
- DOI:
- 10.4238/2014.April.14.9