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Geometry applied to breeding common beans (Phaseolus vulgaris)
Authors: J.G. Lima and M.A.P. Ramalho
The primary components of common bean (Phaseolus vulgaris) grain yield (W) are the number of pods (X), the number of grains per pod (Y), and the weight of the grains (Z). In 1964, Grafius suggested using geometry in plant breeding; W corresponds to the volume of a parallelepiped with three axes, X, Y, and Z. Because the cube i.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027873
- DOI:
- 10.4238/gmr.15027873
Increased miR-155-5p expression in dermal mesenchymal stem cells of psoriatic patients: comparing the microRNA expression profile by microarray
Authors: R.X. Hou, R.F. Liu, X.C. Zhao, Y.R. Jia, P. An, Z.P. Hao, J.Q. Li, X.H. Li, G.H. Yin and K.M. Zhang
Mesenchymal stem cells (MSCs) have pleiotropic immuno-modulatory effects and pro-angiogenic ability, leading to the presumption that MSCs may be involved in the pathogenesis of many inflammatory or autoimmune disorders, including psoriasis. In a previous study, we reported the specific gene expression profile ofdermal MSCs fro.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038631
- DOI:
- 10.4238/gmr.15038631
Association between the -1438A/G polymorphism of the serotonin 2A receptor gene and late-onset psoriasis in a Thai population
Authors: C. Ronpirin, T. Tencomnao and J. Wongpiyabovorn
Expression of serotonin 2A receptor (5-HTR2A) is known to increase in psoriasis, a chronic inflammatory skin disease. We investigated a possible association between the -1438A/G single nucleotide polymorphism (rs6311) in the promoter region of 5-HTR2A gene and psoriasis in a Thai population. One hundred and twelve psoriatic pa.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr718
- DOI:
- 10.4238/vol9-1gmr718
Genetic relationship between the Nordestino horse and national and international horse breeds
Authors: D.A.F. Pires, E.G.A. Coelho, J.B. Melo, D.A.A. Oliveira, M.N. Ribeiro, E. Gus Cothran and R. Juras
Knowledge of genetic diversity and relationships between breeds is very important for conservation programs. Hair samples were collected from 393 individual Nordestino horses and genotyped using 14 microsatellite markers in order to investigate the genetic relationship between this breed and 66 international horse breeds. Ther.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027881
- DOI:
- 10.4238/gmr.15027881
Analysis of FKBP10, SERPINH1, and SERPINF1 genes in patients with osteogenesis imperfecta
Authors: C. Barbirato, M. Trancozo, M.R.G.O. Rebou�§as, V. Sipolatti, V.R.R. Nunes and F. Paula
Osteogenesis imperfecta (OI) is a heterogeneous disorder that causes fragility, deformity, and fractures in bones. A large number of genes that are associated with the disease have been identified in the last decade; this makes the genetic diagnosis of OI more difficult. To improve our knowledge of the genetic mutation profile.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038665
- DOI:
- 10.4238/gmr.15038665
Functional analysis of a TGA factor-binding site located in the promoter region controlling salicylic acid-induced NIMIN-1 expression in Arabidopsis
Authors: J.P. Fonseca, M. Menossi, F. Thibaud-Nissen and C.D. Town
TGA factors play a key role in plant defense by binding to the promoter region of defense genes, inducing expression. Salicylic acid (SA) induces the expression of the gene encoding NIMIN-1, which interacts with NPR1/NIM1, a key regulator of systemic acquired resistance. We investigated whether the TGA2-binding motif TGACG located upstream of the NIMIN-1 .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr704
- DOI:
- 10.4238/vol9-1gmr704
A rapid method for isolation of total DNA from pathogenic filamentous plant fungi
Authors: D. GonzÃ?¡lez-Mendoza, R. Argumedo-Delira, A. Morales-Trejo, A. Pulido-Herrera, L. Cervantes-DÃ?Âaz, O. Grimaldo-Juarez and A. AlarcÃ?³n
DNA isolation from some fungal organisms of agronomic importance is difficult because they have cell walls or capsules that are relatively unsusceptible to lysis. We have developed a fast DNA isolation protocol for Fusarium oxysporum, which causes fusarium wilt disease in more than 100 plant species, and for Pyrenochaeta terre.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr680
- DOI:
- 10.4238/vol9-1gmr680
Caspase-3/-8/-9, Bax and Bcl-2 expression in the cerebellum, lymph nodes and leukocytes of dogs naturally infected with canine distemper virus
Authors: H.L. Del Puerto, A.S. Martins, L. Moro, A. Milsted, F. Alves, G.F. Braz and A.C. Vasconcelos
Canine distemper is an immunosuppressive disease caused by the canine distemper virus (CDV). Pathogenesis mainly involves the central nervous system and immunosuppression. Dogs naturally infected with CDV develop apoptotic cells in lymphoid tissues and the cerebellum, but this apoptotic mechanism is not well characterized. To .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr717
- DOI:
- 10.4238/vol9-1gmr717
A literature-based systematic HuGE review and meta-analysis show that CASP gene family polymorphisms are associated with risk of lung cancer
Authors: Z.Y. Zhang, Y. Xuan, X.Y. Jin, X. Tian and R. Wu
The caspase (CASP) gene family is known to be involved in apoptosis, cytokine maturation, cell growth, and differentiation. A large number of single nucleotide polymorphisms (SNPs) in the CASP gene family have been increasingly recognized as important regulators in the development of lung cancer. However, this specific association is still controversial. .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.January.4.22
- DOI:
- 10.4238/2013.January.4.22
Polymorphisms in the LPL gene and their association with growth traits in Jiaxian cattle
Authors: L.S. Gui, Y.M. Huang, J.Y. Hong and L.S. Zan
Previous studies showed that the lipoprotein lipase (LPL) gene was involved in metabolism and transport of lipids, suggesting that the LPL is a potential candidate gene affecting growth traits in animals. The aim of this study was to identify polymorphism in the bovine LPL gene and analyze its possible association with growth .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027590
- DOI:
- 10.4238/gmr.15027590