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Microbial Genetics   Research Article

Molecular evolution of the melanocortin 1-receptor pigmentation gene in rodents

Authors: G.L. Gon�§alves, V.R. Paix�£o-C�´rtes and T.R.O. Freitas

Adaptive variation in the melanocortin 1-receptor gene (MC1R), a key locus in melanogenesis, has been identified in some species of rodents. However, in others, MC1R has no causative role in pigmentation phenotypes despite their coat color variation. In this study, we characterized the rates and patterns of MC1R nucleotide and amino acid sequence evolutio.. Read More»

Genet. Mol. Res. 12(3):
2013.February.28.24
DOI:
10.4238/2013.February.28.24
Human Genetics   Short communication

Abnormal hemoglobin phenotypes in carriers of mild anemia in Latin America

Authors: P.J.A. Zamaro and C.R. Bonini-Domingos

We looked for abnormal hemoglobins in blood samples sent for diagnosis of anemia. Identification of the hemoglobins was made using electrophoretic, chromatographic and molecular procedures. The 2020 blood samples were of patients from various regions of Brazil and from some other Latin American countries. Among the abnormal he.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr721
DOI:
10.4238/vol9-1gmr721
Human Genetics   Research Article

Efficient human paternity testing with a panel of 40 short insertion-deletion polymorphisms

Authors: J.R. Pimenta and S.D.J. Pena

We developed a panel of 40 multiplexed short insertion-deletion (indel) polymorphic loci with widespread chromosomal locations and allele frequencies close to 0.50 in the European population. We genotyped these markers in 360 unrelated self-classified White Brazilians and 50 mother-child-probable father trios with proven pater.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr838
DOI:
10.4238/vol9-1gmr838
Plant Genetics   Research Article

Genetic characterization of pea (Pisum sativum) germplasm from Turkey using morphological and SSR markers

Authors: G. Sar�±kam�±��, R. Yanmaz, S. Ermi��, M. Bak�±r and C. Y�¼ksel

The need for the conservation of plant genetic resources has been widely accepted. Germplasm characterization and evaluation yield information for more efficient utilization of these valuable resources. The aim of the present study was to characterize the pea germplasm conserved at the Aegean Agricultural Research Institute of.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr762
DOI:
10.4238/vol9-1gmr762
Human Genetics   Research Article

Artificial intelligence in the selection of common bean genotypes with high phenotypic stability

Authors: A.M. Corr�ªa, P.E. Teodoro, M.C. Gon�§alves, L.M.A. Barroso,M. Nascimento, A. Santos and F.E. Torres

Artificial neural networks have been used for various purposes in plant breeding, including use in the investigation of genotype x environment interactions. The aim of this study was to use artificial neural networks in the selection of common bean genotypes with high phenotypic adaptability and stability, and to verify their .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028230
DOI:
10.4238/gmr.15028230
Human Genetics   Research Article

Association of the programmed cell death-1 PD1.5 C>T polymorphism with cervical cancer risk in a Chinese population

Authors: X.F. Li, X.Q. Jiang, J.W. Zhang and Y.J. Jia

The association of the programmed cell death-1 PD1.5 C>T polymorphism with cervical cancer risk has not been investigated. In this hospital-based case-control study, we analyzed 256 patients with cervical cancer and 250 healthy controls. Pearson chi-square test was used to examine differences in the distribution of genotype.. Read More»

Genet. Mol. Res. 15(1):
gmr.15016357
DOI:
10.4238/gmr.15016357
Cytogenomics   Research Article

Cloning and molecular characterization of a cDNA encoding a small GTPase from Hevea brasiliensis

Authors: H.L. Li, D. Guo, W.M. Tian and S.Q. Peng

Small GTPases play a critical role in the regulation of a range of cellular processes including growth, differentiation, and intracellular transportation. The cDNA encoding a small GTPase, designated as HbGTPase1, was isolated from Hevea brasiliensis. HbGTPase1 was 882 bp long containing a 612-bp open reading frame encoding a putative protein of 203 amino.. Read More»

Genet. Mol. Res. 12(3):
2013.September.3.7
DOI:
10.4238/2013.September.3.7
Human Genetics   Research Article

Genetic variation in WDR1 is associated with gout risk and gout-related metabolic indices in the Han Chinese population

Authors: L.J. Liu, X.Y. Zhang, N. He K Liu, X.G. Shi, T. Feng, T.T. Geng, D.Y. Yuan, L.L. Kangand T.B. Jin

Gout is the most common form of inflammatory arthritis affecting men, and current evidence suggests that genetic factors contribute to its progression. As a previous study identified that WD40 repeat protein 1 (WDR1) is associated with gout in populations of European descent, we sought to investigate its relationship with this.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027381
DOI:
10.4238/gmr.15027381
Bioinformatics   Research Article

Isolation and identification of new pollen-specific SFB genes in Japanese apricot (Prunus mume)

Authors: P.P. Wang, Z.H. Gao, Z.J. Ni, W.B. Zhuang and Z. Zhang

SFB, a candidate gene for the pollen S gene, has been identified in several species of Prunus (Rosaceae). We isolated 5 new SFB alleles from 6 Japanese apricot (Prunus mume) lines using a specific Prunus SFB primer pair (SFB-C1F and Pm-Vb), which was designed from conserved regions of Prunus SFB. The nucleotide sequences of these SFB genes were submitted .. Read More»

Genet. Mol. Res. 12(3):
2013.September.3.5
DOI:
10.4238/2013.September.3.5
Plant Genetics   Research Article

Analysis of QTLs for panicle exsertion and its relationship with yield and yield-related traits in rice (Oryza sativa L.)

Authors: C.F. Zhao, T. Chen*, Q.Y. Zhao, L.H. Zhou, L. Zhao, Y.D. Zhang, Z. Zhu, S. Yao and C.L. Wang

Panicle exsertion (PE) is an important morphological trait that is closely associated with spikelet fertility and grain yield. To understand the genetic basis of PE and its relationships with yield and yield-related traits, a recombinant inbred population consisting of 240 lines derived from a cross between an Indica cultivar .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027423
DOI:
10.4238/gmr.15027423