Se
Sequence characterization of cytochrome P450 CYP6P9 in pyrethroid resistant and susceptible Anopheles funestus (Diptera: Culicidae)
Authors: T.S. Matambo, M.J.I. Paine, M. Coetzee and L.L. Koekemoer
Anopheles funestus, one of the main African malaria vectors, caused a major malaria outbreak in South Africa during 1999/2000, even though South Africa had an effective vector control program in place. The outbreak was due to pyrethroid resistant An. funestus invading KwaZulu/Natal. Increased activity of cytochrome P450 (monoo.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr719
- DOI:
- 10.4238/vol9-1gmr719
Lack of association between glutathione S-transferase polymorphisms and primary glioma in a case-control study in Rio de Janeiro
Authors: P. Coutinho, V. Sandim, J.A. Oliveira, G. Alves and A. Hatagima
The glutathione S-transferases (GSTs), a family of phase II isozymes, detoxify several carcinogens. Genetic variations in GSTs have been associated with increased risk for cancer due to a heritable deficiency in detoxification pathways for environmental carcinogens. Conflicting findings have been reported about the association.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr753
- DOI:
- 10.4238/vol9-1gmr753
A fast and simple method for the polymerase chain reaction-based sexing of livestock embryos
Authors: K.C.S. Tavares, I.S. Carneiro, D.B. Rios, C. Feltrin, A.K.C. Ribeiro, S. Gaud�ªncio-Neto, L.T. Martins, L.H. Aguiar, C.R. Lazzarotto, C.E.M. Calder�³n, F.E.M. Lopes, L.P.R. Teixeira, M. Bertolini and L.R. Bertolini
Embryo sexing is a powerful tool for livestock producers because it allows them to manage their breeding stocks more effectively. However, the cost of supplies and reagents, and the need for trained professionals to biopsy embryos by micromanipulation restrict the worldwide use of the technology to a limited number of speciali.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017476
- DOI:
- 10.4238/gmr.15017476
Positional effects of polymorphisms in probe-target sequences on genoplot images of oligonucleotide microarrays
Authors: T.L. Cui, H. Nakaoka, K. Akiyama, H. Kamura, K. Hosomichi, J. Bae, H. Cheong, H. Shin, T. Yada and I. Inoue
Single nucleotide polymorphisms (SNPs) present in probetarget sequences (SPTS) have been shown to be associated with abnormal genoplot images. We explored the effects of SPTS positions on genoplot images using a data set from a genome-wide association study typed on an Illumina Human Hap300 platform. We screened the physical g.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr737
- DOI:
- 10.4238/vol9-1gmr737
Isolation of a novel lipase from a metagenomic library derived from mangrove sediment from the south Brazilian coast
Authors: G.H. Couto, A. Glogauer, H. Faoro, L.S. Chubatsu, E.M. Souza and F.O. Pedrosa
A novel gene coding for a LipA-like lipase with 283 amino acids and a molecular mass of 32 kDa was isolated and characterized from a metagenomic library prepared from mangrove sediment from the south Brazilian coast. LipA was 52% identical to a lipolytic enzyme from an uncultured bacterium and shared only low identities (≤3.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr738
- DOI:
- 10.4238/vol9-1gmr738
Role of a homozygous A(TA)7TAA promoter polymorphism and an exon 1 heterozygous frameshift mutation UGT1A1 in Crigler-Najjar syndrome type II in a Thai neonate
Authors: P. Nilyanimit, A. Krasaelap, M. Foonoi, V. Chongsrisawat and Y. Poovorawan
Crigler-Najjar syndrome is a rare autosomal recessive disease caused by mutations in the UGT1A1 gene. These mutations result in the deficiency of UGT1A1, a hepatic enzyme essential for bilirubin conjugation. This report describes the case of a 4-month-old boy with the cardinal symptoms of Crigler-Najjar syndrome type II. Molecular genetic analysis showed .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.5
- DOI:
- 10.4238/2013.September.4.5
Association between a polymorphism of the �±-lactalbumin gene and milk production traits in Chinese Holstein cows
Authors: J.P. Zhou and C.H. Dong
The traits particularly important for milk production include milk yield, protein percentage, fat percentage, and the somatic cell score. Alpha-lactalbumin (α-LA) is an important whey protein of cow milk, and is also present in the milk of many other mammalian species. In this study, we analyzed the genetic polymorphisms of the α-LA gene and t.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.3
- DOI:
- 10.4238/2013.September.4.3
Association analysis of yield and fiber quality traits in Gossypium barbadense with SSRs and SRAPs
Authors: X.Q. Wang, Y. Yu, W. Li, H.L. Guo, Z.X. Lin and X.L. Zhang
Cotton is an important cash crop. Mining for quantitative trait loci related to yield and fiber quality traits using association analysis has many advantages for cotton research. In this study, 170 simple sequence repeats (SSRs) and 258 sequence-related amplified polymorphisms (SRAPs) were used to analyze the association of 3 yield component traits and 5 .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.4.1
- DOI:
- 10.4238/2013.September.4.1
Molecular characterization of Aspergillus flavus and aflatoxin contamination of wheat grains from Saudi Arabia
Authors: A.S. Al-Wadai, M.R. Al-Othman, M.A. Mahmoud and A.R.M. Abd El-Aziz
Twelve species belonging to six fungal genera were found to be associated with wheat (Triticum aestivum L.) grain samples collected from three main regions in Saudi Arabia. The most common genera (average frequency) were Aspergillus (14.3%), Fusarium (29.1%), Penicillium (9.3%), and Alternaria (8.2%). Nineteen isolates of Aspergillus flavus were screened .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.10
- DOI:
- 10.4238/2013.September.3.10
Lignocellulolytic enzymes and bacteria associated with the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae
Authors: R. Koroiva, C.W.O. Souza, D. Toyama, F. Henrique-Silva and A.A. Fonseca-Gessner
We analyzed the digestive activity of the enzymes that digest cellulose and hemicellulose and the bacterial community that is capable of hydrolyzing wood compounds in the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae, which are miners of decomposing submerged tree and bush branches. Based on quantification of reducing sugars, these la.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.April.2.2
- DOI:
- 10.4238/2013.April.2.2