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Cytogenomics   Research Article

Gene expression patterns of invertase gene families and modulation of the inhibitor gene in tomato sucrose metabolism

Authors: Y.L. Zhang, A.H. Zhang and J. Jiang

Patterns of gene expression in the different types of sucrose metabolism in the tomato are highly variable and heritable. This genetic variation causes considerable functional differences. We examined the patterns of expression of invertase (Inv) gene families and an invertase inhibitor (INH) gene involved in elongating roots, hypocotyls, and fruit of the.. Read More»

Genet. Mol. Res. 12(3):
2013.January.24.1
DOI:
10.4238/2013.January.24.1
Medical Genetics   Research Article

Reply to commentary by G. Sikri and S. Dua on the article â??Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edemaâ? published in Genetics and Molecular Research 14 (3): 11562-11572 to the letter published in Genet. Mol. Res. 14 (4): 15904-15905

Authors: L.J. Wu

The object in this study was a Han Chinese population in Lhasa, with 3658 m in altitude from Chengdu, which has 505 m in altitude by air. Within 24 to 48 h before the subjects arrived in the plateau, they completed a basic situation questionnaire, under the guidance of medical staff. Within 24 to 48 h after they reached the plateau, the subjects completed.. Read More»

Genet. Mol. Res. 15(1):
gmr.15016155
DOI:
10.4238/gmr.15016155
Bioinformatics   Research Article

Association between the TRAIL single nucleotide polymorphism rs1131580 and type 2 diabetes mellitus in a Han Chinese population

Authors: M.Y. Yu, P.Q. Zhao, X.H. Yan, B. Liu, Q.Q. Zhang, R. Wang, C.H. Ma, X.H. Liang, F.L. Zhu and L.F. Gao

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is expressed in different tissues and cells, including the pancreas and lymphocytes, and it can selectively induce apoptosis in tumor cells but not in most normal cells. TRAIL plays critical roles in type 1 diabetes mellitus, and is involved in type 2 diabetes mellitus (T2DM). We recent.. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.2
DOI:
10.4238/2013.September.10.2
Cytogenomics   Research Article

Genetic variability in Melipona scutellaris from Rec?´ncavo, Bahia, Brazil

Authors: J.L. Viana, A.K. Francisco, C.A.L. Carvalho and A.M. Waldschmidt

Bees play a key role in pollination and thereby help maintain plant diversity. The stingless bee Melipona scutellaris is an important pollinator in northeastern Brazil because it is endemic to this region. Both deforestation and timber harvesting have reduced the nesting sites for this species, thus reducing its population and range. Genetic studies may h.. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.1
DOI:
10.4238/2013.September.10.1
Microbial Genetics   Research Article

Molecular cloning and functional analysis of MRLC2 in Tianfu, Boer, and Chengdu Ma goats

Authors: H.G. Xu, G.Y. Xu, L. Wan and J. Ma

To determine the molecular basis of heterosis in goats, fluorescence quantitative polymerase chain reaction (PCR) was performed to investigate myosin-regulatory light chain 2 (MRLC2) gene expression in the longissimus dorsi muscle tissues of the Tianfu goat and its parents, the Boer and Chengdu Ma goats. The goat MRLC2 gene was differentially expressed in.. Read More»

Genet. Mol. Res. 12(3):
2013.March.15.7
DOI:
10.4238/2013.March.15.7
Cytogenomics   Research Article

Genetic diversity of gabiroba based on random amplified polymorphic DNA markers and morphological characteristics

Authors: E.S. de Assis, E.F. dos Reis, J.F.N. Pinto, L.A.S. Contim and L.A.S. Dias

The fragmentation of the original vegetation of the Cerrado biome, caused by the expansion of agricultural areas, mainly in central-west Brazil, calls for an assessment of the native population of this vegetation, especially of the species of interest for domestication and sustainable use. The purpose of this study was to characterize the genetic diversit.. Read More»

Genet. Mol. Res. 12(3):
2013.March.11.7
DOI:
10.4238/2013.March.11.7
Medical Genetics   Research Article

Comparative and joint analyses of gene expression profiles under drought and rewatering in Arabidopsis

Authors: Z.H. Xu and W.R. Wu

Drought is a major limiting factor in crop production. Rewatering is a process opposite to drought, allowing plants to recover to their normal physiological state. To understand more thoroughly the set of genes involved in plant response to drought, we comparatively and jointly analyzed the microarray data of drought and rewatering experiments in Arabidop.. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.6
DOI:
10.4238/2013.September.13.6
Cytogenomics   Research Article

Genetic determinants of the defense response of resistant and susceptible pepper (Capsicum annuum) cultivars infected with Phytophthora capsici (Oomycetes; Pythiaceae)

Authors: Y.-L. Zhang, D.-W. Li, Z.-H. Gong, J.-E. Wang, Y.-X. Yin and J.-J. Ji

Based on culture isolation and morphological observation blight-infected pepper plants in Shaanxi Province, China, we identified the pathogen causing pepper phytophthora blight as Phytophthora capsici. Varieties that differed in resistance (CM334, PBC602, and B27) were inoculated with this pathogen. The root activity of resistant CM334 variety was the hig.. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.5
DOI:
10.4238/2013.September.13.5
Microbial Genetics   Research Article

Molecular analysis of the SMN gene mutations in spinal muscular atrophy patients in China

Authors: W.L. Liu, F. Li, Z.X. He, R. Ai and H.W. Ma

Spinal muscular atrophy (SMA) is one of the most common autosomal recessive diseases. Survival motor neuron1 (SMN1) is the SMA disease-determining gene. We examined the molecular basis of SMA in 113 Chinese SMA patients. Homozygous exon 7 and 8 deletions in SMN1 were detected by PCR-RFLP. Heterozygous deletion of SMN1 was analyzed based on variation of th.. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.4
DOI:
10.4238/2013.September.13.4
Microbial Genetics   Research Article

Mutagenicity, genotoxicity, and scavenging activities of extracts from the soft coral Chromonephthea braziliensis: a possibility of new bioactive compounds

Authors: R.M. Carpes, B.G. Fleury, B.G. Lages, A.C. Pinto, C.A.F. Aiub and I. Felzenszwalb

Coral reefs are diverse ecosystems that have a high density of biodiversity leading to intense competition among species. These species may produce unknown substances, many with pharmacological value. Chromonephthea braziliensis is an invasive soft coral from the Indo-Pacific Ocean that is possibly transported by oil platforms and whose presence can be a .. Read More»

Genet. Mol. Res. 12(3):
2013.September.13.2
DOI:
10.4238/2013.September.13.2