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Plant Genetics   Research Article

Altered callose deposition during embryo sac formation of multi-pistil mutant (mp1) in Medicago sativa

Authors: H.C. Zhou, L. Jin, J. Li and X.J. Wang

Whether callose deposition is the cause or result of ovule sterility in Medicago sativa remains controversial, because it is unclear when and where changes in callose deposition and dissolution occur during fertile and sterile embryo sac formation. Here, alfalfa spontaneous multi-pistil mutant (mp1) and wild-type plants were u.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027968
DOI:
10.4238/gmr.15027968
Animal Genetics   Research Article

Cloning and functional analysis of goat SWEET1

Authors: L.Q. Zhu, Z.K. Bao, W.W. Hu, J. Lin, Q. Yang and Q.H. Yu

SWEETs are a recently discovered class of sugar transporters that mediate glucose uptake in the intestine and mammary glands. Our objectives were to clone goat SWEET1 and conduct a functional analysis of its effect on glucose efflux in goat mammary gland epithelial cells. We cloned and sequenced the goat SWEET1 gene from goat mammary glands, then conducte.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.12
DOI:
10.4238/2015.December.16.12
Human Genetics   Research Article

Analysis of genetic diversity of Laeliinae (Orchidaceae) in the State of Sergipe using ISSR markers

Authors: M.F. Arrigoni-Blank, M.S. Santos, A.F. Blank, A.R.C. Rabbani, R. Silva-Mann, J.B. Santos, A.S. Costa and T.S.A. Menezes

The Orchidaceae represent one of the largest and most diverse families on the planet. However, this family is constantly threatened by predators and by the advancement of urban centers over its natural habitats. The objective of this study was to use inter-simple sequence repeat markers to evaluate the genetic diversity betwee.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027997
DOI:
10.4238/gmr.15027997
Animal Genetics   Research Article

New polymorphic microsatellite loci of threadsail filefish, Stephanolepis cirrhifer (Teleostei, Monacanthidae), from Korean waters

Authors: C.-M. An, H.S. An, J.W. Lee and S.W. Hong

The threadsail filefish, Stephanolepis cirrhifer (Monacanthidae), is found mainly in the western Pacific. It is intensively caught in Korea and is a highly appreciated seafood delicacy. Consequently, the natural population of this species has drastically decreased, despite introductions from hatcheries. To provide information necessary for its conservatio.. Read More»

Genet. Mol. Res. 12(2):
2013.May.14.8
DOI:
10.4238/2013.May.14.8
Human Genetics   Research Article

Study of the relationship between IL-10 polymorphism and serum lipoprotein levels in Han Chinese individuals

Authors: W.Q. Yang

Previous studies have shown that cytokines can affect serum lipoprotein concentrations. The aim of this study was to examine the association between IL-10 gene polymorphisms and serum lipoprotein levels of Han Chinese individuals. A total of 359 Han Chinese people were enrolled in this investigation. IL-10 -592, -819, and -108.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028016
DOI:
10.4238/gmr.15028016
Plant Genetics   Research Article

Isolation and characterization of microsatellite markers for Osmanthus fragrans (Oleaceae) using 454 sequencing technology

Authors: W.J. Yuan, Y. Li, Y.F. Ma, Y.J. Han and F.D. Shang

Osmanthus fragrans (Oleaceae) is an evergreen shrub or small tree that grows in south China. In this study, Roche 454 FLX+ sequencing combined with the magnetic bead enrichment method was used to isolate microsatellite markers from the genome of O. fragrans. A total of 1471 microsatellites that contained enough flanking sequences for primer pair design we.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.15
DOI:
10.4238/2015.December.16.15
Human Genetics   Research Article

Single-nucleotide polymorphisms in dopamine receptor D1 are associated with heroin dependence but not impulsive behavior

Authors: J.H. Liu,H.J. Zhong,J. Dang,L. Peng and Y.S. Zhu

Previous studies suggested that dopamine receptors may be associated with drug dependence and impulsive behavior. In this study, we examined whether dopamine receptor D1 (DRD1) is associated with heroin dependence and the impulsive behavior in patients with heroin dependence. The participants included 367 patients with heroin dependence and 372 healthy co.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.19
DOI:
http://dx.doi.org/10.4238/2015.April.27.19
Human Genetics   Research Article

Association between NOS3 genetic variants and coronary artery disease in the Han population

Authors: G.L. Zhao, Q.J. Li and H.Y. Lu

The enzyme endothelial nitric oxide synthase (NOS3) is an important mediator of atherosclerotic disease and is associated with coronary artery disease (CAD). There is growing evidence that polymorphisms in NOS3 influence the progression of CAD; however, there is also a controversy regarding the association of polymorphisms in .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028044
DOI:
10.4238/gmr.15028044
Medical Genetics   Research Article

R337H mutation of the TP53 gene as a clinical marker in cancer patients: a systematic review of literature

Authors: L.M. Borges and F.M. Ayres

The germline R337H mutation of the TP53 gene has been associated with the development of many tumor types. This systematic review of literature investigated the association between the R337H mutation and the patients’ family history and its predictive and prognostic value in cancer. Data were collected from articles archived in the PubMed, LILACS, M.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.4
DOI:
10.4238/2015.December.16.4
Human Genetics   Research Article

Interaction between ALOX5AP-SG13S114A/T and COX-2-765G/C increases susceptibility to cerebral infarction in a Chinese population

Authors: X.Y. Yi, Q. Zhou, J. Lin, L.F. Chi and W.Z. Chi

We made a case-control study to investigate a possible association between ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T polymorphisms with cerebral infarction in a Chinese population. A total of 411 cases with cerebral infarction were included; 411 controls matched for age, gender, and risk factors were also selected. The ALOX5AP-SG13S114A/T (rs1050.. Read More»

Genet. Mol. Res. 12(2):
2013.May.14.6
DOI:
10.4238/2013.May.14.6