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Plant Genetics   Research Article

A SCAR marker for the analysis of chloroplast DNA from different cultivars of Cornus officinalis

Authors: L. Zhang, R.X. Liu, J. Wang, T. Zhang, J. Li, J.H. Shi, B.Y. Kang and S.Q. Chen

The aims of this study were to establish a random amplified polymorphic DNA (RAPD) fingerprint database of chloroplast DNA (cpDNA) from different cultivars of Cornus officinalis and to convert RAPD markers to sequence characterized amplified regions (SCAR) markers. A method of extraction was established that was suitable for obtaining cpDNA from samples r.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.17
DOI:
10.4238/2015.December.16.17
Animal Genetics   Research Article

Distribution of LIM domain kinase 1 in the olfactory bulb, cerebral cortex, hippocampus, and cerebellum of the App/PS+/- mice

Authors: L. An, J. Liu, W.W. Li, Y.J. Shi, X.H. Lin, D.M. Yu, J.B. Deng and X.Q. Ren

LIM domain kinase 1 (LIMK1), an actin-binding kinase, can phosphorylate and inactivate its substrates, and can regulate long-term memory and synaptic plasticity. Both β-amyloid precursor protein (App) and presenilin (PS) are functional degeneration factors during early neuronal development, and are considered as potential factors that contribute to t.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.24
DOI:
10.4238/2015.December.16.24
Medical Genetics   Research Article

Major quality trait analysis and QTL detection in hexaploid wheat in humid rain-fed agriculture

Authors: H.M. Li, Z.X. Tang, H.Q. Zhang, B.J. Yan and Z.L. Ren

Humid rain-fed agriculture is a special environment for wheat (Triticum aestivum) culture that tends to negatively affect wheat yield and quality. To identify quality characters of wheat in a humid environment, we conducted quality analysis and quantitative trait loci (QTL) detection in a recombinant inbred line whose parent had a high level of quality fo.. Read More»

Genet. Mol. Res. 12(2):
2013.May.21.5
DOI:
10.4238/2013.May.21.5
Animal Genetics   Research Article

Identification of genes and pathways related to lipopolysaccharide signaling in duckling spleens

Authors: B. Deng, T. Yu, W. Liu, S.Q. Ye, L.X. Wang, Y. Yang, P. Gong, Z.P. Ran, H.J. Huang and J.H. Wen

Lipopolysaccharide (LPS), the major component of the outer cell wall of Gram-negative bacteria, activates the immune system and threatens the health of livestock and poultry. However, little is known about the genes and pathways involved in the immune response of ducklings to LPS. To elucidate the genes involved in the response of 7-day-old duckling splee.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.32
DOI:
10.4238/2015.December.16.32
Plant Genetics   Research Article

Genetic potential of segregating populations of red beans conducted by the bulk method with selection

Authors: J.A.N. Menezes J�ºnior, J.E.S. Carneiro, V.M.P.S. Menezes and P.C.S. Carneiro

This study evaluated the performance and estimated the genetic potential of segregating populations of red bean. Twenty populations of the second cycle of recurrent selection for red bean breeding at Universidade Federal de Viçosa were advanced to the F5 generation in bulk with selection for grain appearance. Population.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027329
DOI:
10.4238/gmr.15027329
Microbial Genetics   Research Article

Analysis of the beta-globin gene in DNA of suspected thalassemic great apes

Authors: J. Vuch, M.S. Siori, M.P. Bigatti, L. Segat, G. De Fabrizio and S. Crovella

DNA was recovered from teeth of 2 great ape skeletons, Pan troglodytes (Ptr) and Pongo pygmaeus (Ppy), belonging to a 19th-century zoological collection. The skeletons presented morphological alterations possibly associated with β-thalassemia: Ptr had deformation of the calvaria and oro-maxillo-facial bones with porotic hyperostosis and extend.. Read More»

Genet. Mol. Res. 12(2):
2013.May.21.4
DOI:
10.4238/2013.May.21.4
Human Genetics   Research Article

Expression of IL-21 in rats with inflammatory bowel disease

Authors: J.N. Mao, Y.S. Shen, X.Y. Luo and Y.L. Zhi

The purpose of this study was to investigate the expression of interleukin (IL)-21 in rats with inflammatory bowel disease (IBD). Fifty adult Wistar rats were randomly divided into two groups: DSS, in which IBD was induced by giving the rats 7% DSS for seven days in their water, and a water control. Blood samples were collected and the concentration of IL.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.33
DOI:
10.4238/2015.December.16.33
Animal Genetics   Research Article

A single nucleotide polymorphism in GABAA receptor isoforms is potentially responsible for isoflurane sensitivity in mice

Authors: X. Wang, Z.G. Song, D.X. Huang, H. Gao, Q. Wang and Z.P. Wang

GABAA receptors are chloride channels in the brain that are activated by binding with g-aminobutyric acid (GABA). The cDNA sequences of GABAA receptor subunits from two strains of mice with different sensitivities to isoflurane were compared to identify nucleotide mutations. Included 80 mice from two strains with different sen.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027340
DOI:
10.4238/gmr.15027340
Plant Genetics   Research Article

In silico characterization of putative members of the coffee (Coffea arabica) ethylene signaling pathway

Authors: A.A. Lima, S.A. S�¡gio, A. Chalfun-J�ºnior and L.V. Paiva

The plant hormone ethylene is involved in several developmental and physiological processes in plants, including senescence, fruit ripening and organ abscission, as well as in biotic and abiotic stress responses. Initiation of these processes involves complex regulation of both ethylene biosynthesis and the ability of cells to.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1314
DOI:
10.4238/vol10-2gmr1314
Human Genetics   Research Article

Genetic parameters for carcass traits and body weight using a Bayesian approach in the Canchim cattle

Authors: S.L.C. Meirelles, F.B. Mokry, A.C. Espasand�­n, M.A.D. Dias, M.M. Baena and L.C. de A. Regitano

Correlation between genetic parameters and factors such as backfat thickness (BFT), rib eye area (REA), and body weight (BW) were estimated for Canchim beef cattle raised in natural pastures of Brazil. Data from 1648 animals were analyzed using multi-trait (BFT, REA, and BW) animal models by the Bayesian approach. This model i.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027471
DOI:
10.4238/gmr.15027471