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A minimal DNA cassette as a vector for genetic transformation of soybean (Glycine max)
Authors: G.R. Vianna, F.J.L. Arag�£o and E.L. Rech
Currently, the market demands products committed to protecting human health and the environment, known as clean products. We developed a protocol using DNA fragments containing only the gene sequence of interest, to replace the circular vectors containing genes for antibiotic resistance and other undesirable sequences, for obt.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1058
- DOI:
- 10.4238/vol10-1gmr1058
Lack of association of single nucleotide polymorphisms of the bovine Flt-1 gene with growth traits in Chinese cattle breeds
Authors: Y.H. Pang, C.Z. Lei, C.L. Zhang, X.Y. Lan, S. Shao, X.M. Gao, J.Q. Wang and H. Chen
We analyzed 20 exons, with their intron-exon boundaries, of the bovine Flt-1 gene, using a strategy combining PCR amplification and single-strand conformational polymorphism analysis (PCR-SSCP), followed by nucleotide sequence analysis, in 675 cattle. We then looked for associations between polymorphisms and growth traits. Twe.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1041
- DOI:
- 10.4238/vol10-1gmr1041
Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study
Authors: T. Hasi, L. Hao, L. Yang and X.L. Su
Mongolians are known as heavy drinkers, and they have a high incidence of essential hypertension, which may be an associated pathology. We examined a possible association of essential hypertension and polymorphism of the aldehyde dehydrogenase 2 (ALDH2) gene in Mongolians from Inner Mongolia. Single nucleotide polymorphism rs6.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1056
- DOI:
- 10.4238/vol10-1gmr1056
Clinical application of high-sensitivity cardiac troponin T test in acute myocardial infarction diagnosis
Authors: J.A. Wang, Y. Qin, J. Lv, Y.F. Tian and Y.J. Dong
The aim of this study was to investigate the clinical application of a high-sensitivity cardiac troponin T (hs-cTnT) test in the diagnosis of acute myocardial infarction (AMI). Serum levels of hs-cTnT and cardiac troponin I (cTnI) were detected in 240 AMI patients and 200 healthy donors and used to plot receiver operating characteristic (ROC) curves. A cl.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.21
- DOI:
- 10.4238/2015.December.22.21
Effective sample selection for classification of pre-miRNAs
Authors: K. Han
To solve the class imbalance problem in the classification of pre-miRNAs with the ab initio method, we developed a novel sample selection method according to the characteristics of pre-miRNAs. Real/pseudo pre-miRNAs are clustered based on their stem similarity and their distribution in high dimensional sample space, respective.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1054
- DOI:
- 10.4238/vol10-1gmr1054
Structural modeling and analysis of dengue-mediated inhibition of interferon signaling pathway
Authors: B. Aslam,J. Ahmad,A. Ali,R.Z. Paracha,S.H.K. Tareen,S. Khusro,T. Ahmad,S.A. Muhammad,U. Niazi and V. Azevedo
Dengue virus (DENV) belongs to the family Flaviviridae and can cause major health problems worldwide, including dengue fever and dengue shock syndrome. DENV replicon in human cells inhibits interferon α and β with the help of its non-structural proteins. Non-structural protein 5 (NS5) of DENV is responsible for the proteasome-mediated degradati.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.28.4
- DOI:
- http://dx.doi.org/10.4238/2015.April.28.4
Assessment of CASP gene polymorphisms in periodontal disease
Authors: S.W. Kang, S.K. Kim, J.H. Chung and J.Y. Ban
Caspases (CASP) are intracellular proteases that play roles as mediators of apoptosis. Activation of caspase 3 is enhanced in chronic periodontitis. Thus, we hypothesized that single nucleotide polymorphisms (SNPs) of CASP genes might be associated with this condition in the Korean population. To investigate whether such polymorphisms might be involved in.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.33
- DOI:
- 10.4238/2015.December.22.33
Agro-ecological variations of sheath rot disease of rice caused by Sarocladium oryzae and DNA fingerprinting of the pathogen�s population structure
Authors: M. Tajul Islam Chowdhury, M. Salim Mian, M.A. Taher Mia, M.Y. Rafii and M.A. Latif
To examine the impact of regional and seasonal variations on the incidence and severity of sheath rot, a major seed-borne disease of rice caused by Sarocladium oryzae, data on incidence and severity were collected from 27 selected fields in the Gazipur, Rangpur, Bogra, Chittagong, Comilla, Gopalgonj, Jessore, Manikgonj, and Bhola districts of Bangladesh i.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.1
- DOI:
- 10.4238/2015.December.23.1
Relationships between transient elastography values and liver fibrosis in chronic liver disease patients with normal or mildly abnormal aminotransferase levels
Authors: Y.P. Zhang, Q. Zhao, Y.Z. Tao, X.R. Niu and L. Rui
This study aimed to evaluate relationships between transient elastography values and liver fibrosis in chronic liver disease patients with normal or mildly abnormal aminotransferase levels. Fifty-six patients were enrolled in the study. Transient elastography and liver biopsy were performed on the same day, and the fibrosis was staged based on the Scheuer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.4
- DOI:
- 10.4238/2015.December.23.4
Complete mitochondrial genome of the Southern catfish (Silurus meridionalis Chen) and Chinese catfish (S. asotus Linnaeus): Structure, phylogeny, and intraspecific variation
Authors: Q.R. Wang, C. Xu, C.R. Xu and R.J. Wang
The complete mitochondrial genome of the Southern catfish (Silurus meridionalis) and the Chinese catfish (S. asotus), was determined using the long and accurate polymerase chain reaction (LA-PCR) method. The mitochondrial DNA nucleotide sequences of S. meridionalis and S. asotus were compared with those of 47 other catfish species in the same order. The t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.7
- DOI:
- 10.4238/2015.December.23.7