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Segregation analysis of microsatellite (SSR) markers in sugarcane polyploids
Authors: X. Lu, H. Zhou, Y.-B. Pan, C.Y. Chen, J.R. Zhu, P.H. Chen, Y.-R. Li, Q. Cai and R.K. Chen
No information is available on segregation analysis of DNA markers involving both pollen and self-progeny. Therefore, we used capillary electrophoresis- and fluorescence-based DNA fingerprinting together with single pollen collection and polymerase chain reaction (PCR) to investigate simple sequence repeat (SSR) marker segregation among 964 single pollens.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.26
- DOI:
- 10.4238/2015.December.23.26
Aldehyde dehydrogenase 2 (ALDH2) polymorphism gene and coronary artery disease risk: a meta-analysis
Authors: L.L. Zhang, Y.Q. Wang, B. Fu, S.L. Zhao and Y. Kui
We studied the association between aldehyde dehydrogenase 2 (ALDH2) polymorphism and coronary artery disease (CAD) and clarified the mechanisms underlying this association. We searched the ISI, Medline (Ovid), PubMed, CNKI, Wanfang, and Weipu Databases. Statistical analysis was performed using Revman 5.0 and Stata12.0 softwares. A total of 3305 cases and .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.38
- DOI:
- 10.4238/2015.December.23.38
Molecular cloning and expression analysis of a novel BCCP subunit gene from Aleurites moluccana
Authors: W.Y. Xuan, Y. Zhang, Z.Q. Liu, D. Feng and M.Y. Luo
Aleurites moluccana L. is grown as a roadside tree in southern China and the oil content of its seed is higher than other oil plants, such as Jatropha curcas and Camellia oleifera. A. moluccana is considered a promising energy plant because its seed oil could be used to produce biodiesel and bio-jet fuel. In addition, the bark, leaves, and kernels of A. m.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.27
- DOI:
- 10.4238/2015.August.19.27
Association of TNF-�±, CTLA4, and PTPN22 polymorphisms with type 1 diabetes and other autoimmune diseases in Brazil
Authors: N.A.C. Tavares, M.M.S. Santos, R. Moura, J. Ara�ºjo, R.L. Guimar�£es, S. Crovella and L.A.C. Brand�£o
Type 1 diabetes mellitus (T1D) is a complex disorder characterized by an autoimmune response against human pancreatic beta-cells. Patients with T1D can also develop a response toward one or more other factors, such as in autoimmune thyroiditis (AITD) and celiac disease (CD). In the presence of T1D + AITD, the patient is diagnosed with autoimmune polygland.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.28.42
- DOI:
- 10.4238/2015.December.28.42
Genetic diversity analysis of sweet kernel apricot in China based on SSR and ISSR markers
Authors: M.P. Liu, H.Y. Du, G.P. Zhu, D.L. Fu and W.Y. Tana
Simple sequence repeat (SSR) and inter-simple sequence repeat (ISSR) markers were used to evaluate genetic diversity among 22 sweet kernel apricot accessions and 12 cultivars in China to provide information on how to improve the utilization of kernel apricot germplasms. The results showed that 10 pairs of SSR primers screened from 40 primer pairs amplifie.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.4
- DOI:
- 10.4238/2015.August.19.4
Identification of conservation units of the hynobiid salamander Pachyhynobius shangchengensis
Authors: L.-N. Su, Y.-Y. Zhao, X.-M. Wu, H.-F. Zhang and X.-C. Li
The evolutionary significant units (ESUs) of the salamander Pachyhynobius shangchengensis (Hynobiidae) in the Dabieshan mountains, southeastern China, were identified based on mitochondrial DNA data. We used methods for detecting cryptic species, such as the minimum spanning tree, the automatic barcode gap discovery, and the generalized mixed Yule-coalesc.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.10
- DOI:
- 10.4238/2015.August.19.10
APOA5 -1131T>C and APOC3 -455T>C polymorphisms are associated with an increased risk of coronary heart disease
Authors: Y. Sun, R.B. Zhou and D.M. Chen
The aim of this study was to investigate correlations between apolipoprotein A-V (APOA5) -1131T>C and apolipoprotein C-III (APOC3) -455T>C polymorphisms and coronary heart disease (CHD). PubMed, Ovid, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched using combinations of keywords relating to thes.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.9
- DOI:
- 10.4238/2015.December.23.9
Expression pattern of JMJD1C in oocytes and its impact on early embryonic development
Authors: C.H. Li, Y. Gao, S. Wang, F.F. Xu, L.S. Dai, H. Jiang, X.F. Yu, C.Z. Chen, B. Yuan and J.B. Zhang
Cell reprogramming mediated by histone methylation and demethylation is crucial for the activation of the embryonic genome in early embryonic development. In this study, we employed quantitative real-time polymerase chain reaction (qRT-PCR) to detect mRNA levels and expression patterns of all known histone demethylases in early germinal vesicle stage and .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.12
- DOI:
- 10.4238/2015.December.23.12
Effect of Ginkgo biloba extract on matrix metalloproteinase-3 expression in a rat model of chondrocyte injury
Authors: J.Z. Zeng, L.F. Ma, H. Meng, H.M. Yu, Y.K. Zhang and A. Guo
A rat model with cartilage chondrocyte injury was established using interleukin-1β (IL-1β) to investigate the effect of Ginkgo biloba extract (EGb) on matrix metalloproteinase-3 (MMP-3) expression. Rat chondrocytes were extracted and randomly divided into six groups: control group, IL-1β (model) group, IL-1β + dexamethasone group, and .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.15
- DOI:
- 10.4238/2015.December.23.15
Cloning and characterization of ADP-glucose pyrophosphorylase small subunit gene in Cyperus esculentus (yellow nutsedge)
Authors: C. Cheng, J. Hu, Y. Zhi, J.J. Su, X.K. Zhang and B.Q. Huang
ADP-glucose pyrophosphorylase (ADPGlcPPase) controls the first committed step of starch synthesis by catalyzing the biosynthesis of ADP-glucose from glucose-phosphate and ATP. It is a tetrameric protein consisting of two small and two large subunits. The small subunits have a catalytic function, while the large subunits regulate the enzyme activity. Cyper.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.18
- DOI:
- 10.4238/2015.December.23.18