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Soybean Stem Fly, Melanagromyza sojae (Diptera: Agromyzidae), in the New World: detection of high genetic diversity from soybean fields in Brazil
Authors: J.A. Arnemann, W.T. Tay, T.K. Walsh H. Brier, K. Gordon,F. Hickmann, G. Ugalde and J.V.C. Guedes
Soybean Stem Fly (SSF), Melanagromyza sojae (Zehntner), belongs to the family Agromyzidae and is highly polyphagous, attacking many plant species of the family Fabaceae, including soybean and other beans. SSF is regarded as one of the most important pests in soybean fields of Asia (e.g., China, India), North East Africa (e.g.,.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028610
- DOI:
- 10.4238/gmr.15028610
Predictive potential role of glutathione S-transferase polymorphisms in the prognosis of breast cancer
Authors: X. Wang and Z.H. Huang
The current study aimed at evaluating the association between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients. Genotyping of GSTP1 rs1695, GSTT1 deletion, and GSTM1 deletion was performed by Polymerase Chain Reaction Restriction Fragment Length.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.7
- DOI:
- 10.4238/2015.August.28.7
Genomic characterization and sequence diversity of the �²2-microglobulin gene in the miiuy croaker, Miichthys miiuy
Authors: Y.N. Sun, X.R. Su, T.J. Xu and T.W. Li
β2-Microglobulin (β2m) is related to major histocompatibility complex class I alpha chains, and forms cell-surface glycoproteins that mediate a variety of functions in immune defense. In general, β2m has no isoforms and is not polymorphic in higher vertebrates, but polymorphisms between different alleles have been found in some fish species.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.9
- DOI:
- 10.4238/2015.August.28.9
Investigation of single nucleotide polymorphisms in phosphodiesterase 4D gene in Mongol and Han patients with ischemic stroke in Inner Mongolia
Authors: J.P. Shi, W.D. Chen, J.Q. Zhou, M.M. Xue, F. Xue, H.Z. Li and Z.P. Xu
We investigated single nucleotide polymorphisms (SNP) at 87 sites of the phosphodiesterase 4D (PDE4D) gene in Mongol and Han patients with ischemic stroke in Inner Mongolia. SNPs in 226 patients with ischemic stroke (case group, 110 Mongol patients, 116 Han patients) and 220 patients without neurological disease (control group, 102 Mongol patients, 118 Ha.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.13
- DOI:
- 10.4238/2015.August.28.13
Whole-transcriptome sequencing of Pinellia ternata using the Illumina platform
Authors: X. Huang, Y. Jing, D.J. Liu, B.Y. Yang, H. Chen and M. Li
Pinelliae rhizoma is the dried tuber of Pinellia ternata (Thunb.) Breit., and has been used for thousands of years as a traditional Chinese medicine. However, its genomic background is little known. With the development of high-throughput genomic sequencing, it is now easy and cheap to obtain genomic information. In this study.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028062
- DOI:
- 10.4238/gmr.15028062
Phylogenetic relationships of Pseudohynobius (Urodela, Hynobiidae) inferred from DNA barcoding analysis
Authors: Y.-Y. Zhao, L.-N. Su, Z.-M. Zhang and X.-Y. Wang
As a proven tool, DNA barcoding can identify species rapidly and unambiguously. In this study, we used mtDNA cyt b, COI, and 16s rRNA sequences of six species of Pseudohynobius, Protohynobius puxiongensis, Liua shihi, Ranodon sibiricus, and Pachyhynobius shangchengensis, to reconstruct the phylogenetic relationships using Baye.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028155
- DOI:
- 10.4238/gmr.15028155
Effect of IL-17 monoclonal antibody Secukinumab combined with IL-35 blockade of Notch signaling pathway on the invasive capability of hepatoma cells
Authors: H.CH. Li, Y.X. Zhang, Y. Liu and Q.SH. Wang
We investigated the effect of the IL-17 monoclonal antibody Secukinumab combined with IL-35 in the blockade of the Notch signaling pathway on the invasive capability of hepatoma cells. We examined the effects of IL-17 antibody or IL-35 treatment alone or in combination on cell invasion and migration capabilities with Transwell.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028174
- DOI:
- 10.4238/gmr.15028174
HLA-A gene polymorphisms contribute to osteoporosis susceptibility in postmenopausal Han Chinese women
Authors: S.M. Li, H. Guo, H.J. Yang, M.Q. Lv and D.X. Zhou
Osteoporosis is a common disease characterized by low bone mineral density, deterioration in bone microarchitecture, and increased fracture risk and is more prevalent in postmenopausal women. HLA is a complex gene family; previous studies have shown that it plays an important role in the pathogenesis of osteoporosis among Japanese and Greek populations. P.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.18
- DOI:
- 10.4238/2015.August.28.18
EDA mutation as a cause of hypohidrotic ectodermal dysplasia: a case report and review of the literature
Authors: S.X. Huang, J.L. Liang, W.G. Sui, H. Lin, W. Xue, J.J. Chen, Y. Zhang, W.W. Gong, Y. Dai and M.L. Ou
Ectodermal dysplasia (ED) represents a collection of rare disorders that result from a failure of development of the tissues derived from the embryonic ectoderm. ED is often associated with hair, teeth, and skin abnormalities, which are serious conditions affecting the quality of life of the patient. To date, a large number of genes have been found to be .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.28.21
- DOI:
- 10.4238/2015.August.28.21
Notification of Huntington�s disease as primary cause of death in Brazil from 1984 to 2008
Authors: I.P. Vaz and C.L.A. Paiva
The aim of this article was to conduct a retrospective observational study on reported deaths due to Huntington’s disease (HD) in Brazil in the past 25 years (from 1984 to 2008). Data were obtained from the Brazilian Mortality Information System (SIM/DATASUS), the official system of Brazilian Mortality Database. The data.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028257
- DOI:
- 10.4238/gmr.15028257