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Characterization of 33 microsatellite markers and development of multiplex PCR for yellow-throated marten (Martes flavigula)
Authors: Mu-Yeong Lee, Hea Chang Moon, Hey Sook Jeon, Eui-Geun Song, Donggul Woo, HeeBok Park, Tae-Young Choi, Kyung-Yeon Eo, Yongsun Hyun, Kangbok Lee, Young-Seok Park, Ju-Young Moon, Hyun-Jin Han, Junghwa An
The yellow-throated marten (Martes flavigula Boddaert 1785) is a medium-sized carnivore and a top predator in South Korea that is distributed throughout Western and Southeast Asia and Siberia in a wide range of habitats. In this study, we developed a panel of polymorphic microsatellite markers for M. flavigula by Illumina next.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039854
- DOI:
- 10.4238/gmr16039854
Differential expression of trypsin-3 and phosrestin II genes in the main malaria vector, Anopheles darlingi, from the Brazilian Amazon region
Authors: Ohse, K.C, Matiolli, C.C, Scarpassa, V.M, Santos, V. S, Tadei, W. P, Rafael, M. S
Anopheles darlingi is the most anthropophilic mosquito related to Plasmodium infection of malaria, causing significant morbidity and mortality in South America. Pyrethroid chemical has been used to control mosquitos. We analyzed the expression of trypsin-3 and phosrestin II genes implicated to feeding and resistance to insecti.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039852
- DOI:
- 10.4238/gmr16039852
Characterization of molecular hemoglobin c and beta thalassemia
Authors: M.H. Lagares, M.S. Rabelo, C.G.B. Dias-penna, R.S. Mascarenhas, K.S.F. Silva and K.K.V.O. Moura
The hemoglobinopathies are a group of hereditary alterations prevalent in many parts of the world, but significantly affect the Brazilian population for its abundant miscegenation. These alterations in structural genes that cause the formation of hemoglobin variants, and/or regulatory genes, causing thalassemias. Currently, th.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039851
- DOI:
- 10.4238/gmr16039851
Pseudo deficiency of acid �±-glucosidase: a challenge in the newborn screening for Pompe diseases
Authors: Diana Rojas M�¡laga, Ana C. Brusius-Facchin, Kristiane Michelin-Tirelli, T�ªmis M. F�©lix, Jaqueline Schulte, Jamile Pereira, Eurico Camargo Neto, Claudio Sampaio Filho, Roberto Giugliani.
When a low activity of acid α-glucosidase (GAA) is found, particularly in newborn screening programs, to differentiate α-glucosidase pseudo deficiency from true Pompe disease is important and urgent, as the result generates parental stress and also because this differentiation drives decisions related to the manage.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039844
- DOI:
- 10.4238/gmr16039844
Identification of Klf6-Related Super Enhancer in Human Hepatoma (HepG2) Cells by CRISPR Technique
Authors: Kum Chol Ri*, Jong Su Kim, Chol Kim
The Klf6 gene is a tumor suppressor gene belonging to the family of the Klf gene and closely associated with tumor formation. Recently, super enhancers(SEs) have been shown to play a particularly important role in regulating cell identity and are attempting to evaluate the in vivo function of SEs. But direct functional evidenc.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039841
- DOI:
- 10.4238/gmr16039841
Genetic diversity between and within half-sib families of Brazil nut tree (Bertholletia excelsa Bonpl.) originating from native forest of the Brazilian Amazon
Authors: L.D. Giustina, A.B. Baldoni, F.D. Tardin, F.S. Gregolin, H. Tonini, L.G. Neves, L.P. Ribeiro, P.E. Teodoro
Brazil nut tree is a species of economic importance for the Amazon region, known for the commercialization of its almonds. The objective of this work was to study the genetic diversity among half-sib progenies from different Brazil nut trees present in native forest in the municipality of Itaúba, MT, belonging to the Br.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039839
- DOI:
- 10.4238/gmr16039839
Phenotypic, genotypic, and environmental correlations between characters in onion segregate populations obtained under different generations
Authors: D.L.M. Machado, J. A. de Freitas, J.M.Q. Luz, G. M. Maciel, A.P.O. Nogueira and E. di Camillo
Onion (Allium cepa L.) is the third most valuable vegetable crop worldwide and the third most produced in Brazil. The knowledge of the nature and the value of the relationship between the traits of interest is very important, since it is possible to select a main trait, with low heritability or difficult measurement, obtaining.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039838
- DOI:
- 10.4238/gmr16039838
Comparison Between Real-Time Polymerase Chain Reaction and DNA-Microarray in Detection and Identification of Mycobacterium Species
Authors: Asaad Gaber, Hzem Hamed, Essam Elsawy
Low-cost and low-density (LCD) DNA arrays offer an easy way to detect resistance as minimal laboratory instrumentation is needed. Nucleic acid-based amplification tests allow the rapid detection of Mycobacterium tuberculosis. Recently, a real-time PCR assay for M. tuberculosis complex was introduced. Real-Time PCR and DNA-micr.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039837
- DOI:
- 10.4238/gmr16039837
Effect of You-Gui-Wan on endometrial angiogenesis in controlled ovarian hyperstimulation mice model
Authors: Qiao-zhi Yin, Ji-Zhong Zhang, Li-min Li�Yu-lin Li, Li Huang, Nan Ning
Purpose: To explore the mechanism of You-Gui-Wan (YGW) in improving endometrial receptivity in mouse model of controlled ovarian hyperstimulation (COH). Methods: Sixty female mice with two consecutive oestrous cycles were randomly divided into COH model group (n = 50) and normal control group (n = 10). The COH model was crea.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039833
- DOI:
- 10.4238/gmr16039833
Improvement of Exercise Intervention on Vascular Endothelial Functions during Prediabetes Mellitus
Authors: Shaobing Wang, Zhenghong Zhang, Yiping Liu, Zhengchao Wang
Prediabetes is considered to be an at a risk state, with an annualized 5-10% conversion rate of diabetes and the similiar proportion converting back to normoglycaemia. The global incidence of prediabetes is increasing and will reach to 471 million patients in 2030. The elevation of blood sugar is a continuum and hence prediabe.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039830
- DOI:
- 10.4238/gmr16039830