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Association between functional polymorphisms in the nitric oxide synthase 3 gene and pediatric acute respiratory distress syndrome
Authors: L. Wei, Y. An and J. Wang
Nitric oxide mediates multiple physiological functions, including neurotransmission, immune regulation, angiogenesis, antiplatelet activity, and surfactant maturation or secretion. Mice deficient in the nitric oxide synthase 3 (NOS3) gene displayed defective lung vascular development and fatal respiratory distress. Polymorphisms in NOS3 have been reported.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038401
- DOI:
- 10.4238/gmr.15038401
Cytochrome c oxidase subunit I barcoding of the green bee-eater (Merops orientalis)
Authors: I.A. Arif, H.A. Khan, M. Shobrak and J. Williams
DNA barcoding using mitochondrial cytochrome c oxidase subunit I (COI) is regarded as a standard method for species identification. Recent reports have also shown extended applications of COI gene analysis in phylogeny and molecular diversity studies. The bee-eaters are a group of near passerine birds in the family Meropidae. .. Read More»
- Genet. Mol. Res. 10(4):
Effect of pregnane X receptor polymorphisms on tacrolimus blood concentrations and the resulting adverse reactions in kidney transplantation recipients
Authors: Z.P. Wang, M. Zhao, Q.S. Qu and S.Z. Miao
We investigated the effect of pregnane X receptor (PXR) polymorphisms on tacrolimus (FK506) blood trough concentrations and the associated adverse reactions in kidney transplantation recipients (KTRs). Polymerase chain reaction (PCR)-restriction fragment length polymorphism was used to detect the genotypes of single nucleotide polymorphism loci in 336 KTR.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038464
- DOI:
- 10.4238/gmr.15038464
Sexing single bovine blastomeres using TSPY gene amplification
Authors: M.C.A. Carneiro, P.L. Takeuchi, A. Ara�ºjo, R.B. L�´bo, F.P. Elias, R.A. Vila, C.L. Miranda-Furtado and E.S. Ramos
The testis-specific protein Y-encoded gene (TSPY) is a Y-specific gene present in variable copy number in many mammalian species, including cattle. We tested the applicability of the TSPY gene as a Y-specific marker to predict preimplantation embryo sex in Nelore (Bos indicus) cattle. Two blastomeres were removed from each emb.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.1
- DOI:
- 10.4238/2011.October.25.1
A novel DDX5 gene in the freshwater crayfish Cherax quadricarinatus is highly expressed during ontogenesis and spermatogenesis
Authors: D.-A. Fang, Q. Wang1, J. Wang, L. He, L.-H. Liu and Y. Wang
The freshwater crayfish Cherax quadricarinatus, originally from Australia, is an invasive species that is also widely used in aquaculture. DEAD-box helicase family genes are found throughout evolution and encode RNA-binding proteins. The human DDX5 (p68) is important for normal cell growth, differentiation and proliferation. W.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.3
- DOI:
- 10.4238/2011.October.25.3
Microarray analysis in caudal medulla of cattle orally challenged with bovine spongiform encephalopathy
Authors: L.M. Almeida, U. Basu, J.L. Williams, S.S. Moore and L.L. Guan
Bovine spongiform encephalopathy (BSE) is a fatal disorder in cattle characterized by progressive neurodegeneration of the central nervous system. We investigated the molecular mechanisms involved in neurodegeneration during prion infection through the identification of genes that are differentially expressed (DE) between expe.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.5
- DOI:
- 10.4238/2011.October.25.5
Genome-wide identification, phylogeny and expression analysis of the lipoxygenase gene family in cucumber
Authors: S.Q. Liu, X.H. Liu and L.W. Jiang
Plant lipoxygenase (LOX) is involved in growth and developmental control processes, through the biosynthesis of regulatory molecules and defense responses to pathogens, wounding and stress. To date, few LOX proteins and little tissue expression profiling have been reported in detail for cucumber (Cucumis sativus L.). Recent co.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.9
- DOI:
- 10.4238/2011.October.25.9
Genetic analysis of the major gene plus polygene model in soybean resistance to Leguminivora glycinivorella
Authors: J. Zhang, D. Yao, J. Ma, Y.-P. Fu, J. Qu and P.-W. Wang
In order to investigate the genetic characteristics of soybean Leguminivora glycinivorella resistance and to improve soybean resistance insectivorous breeding efficiency by applying the multi-generation joint analysis method of the major gene plus polygene model, 5 pedigrees and generations (P1, F1, P2, F2, and F2:3) .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.13
- DOI:
- 10.4238/2014.July.4.13
Expression analysis of self-incompatibility-associated genes in non-heading Chinese cabbage
Authors: L. Wang, C. Wang, T.T. Ge, J.J. Wang, T.K. Liu, X.L. Hou and Y. Li
In Brassicaceae, a self-incompatibility (SI) system mediates pollen-pistil interactions. Self-pollen could be recognized and rejected by incompatible pistils. Several components involved in the SI response have been determined, including S-locus receptor kinase (SRK), S-locus cysteine-rich protein/S-locus protein 11, and arm r.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.18
- DOI:
- 10.4238/2014.July.4.18
Identification and characterization of genes related to cellulolytic activity in basidiomycetes
Authors: A.F.N. Volpini, T. Thomazine, S.H. Umeo, G.A. Pereira, G.A. Linde, J.S. Valle, N.B. Colauto, F.G. Barcellos and S.G.H. Souza
Enzymes produced by basidiomycetes that are involved in the cellulose degradation process, and their respective codifying genes, must be identified to facilitate the development of novel biotechnological strategies and applications in the agro-industry. The objective of this study was to identify prospective cellulase-producing genes and characterize thei.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038722
- DOI:
- 10.4238/gmr.15038722