Single Nucleotide Polymorphisms
Correlation between polymorphisms in the visfatin gene and its expression in the serum and coronary artery calcification
Authors: L.W. Jin, S.B. Zheng, Z.H. Zhou, S.F. Pan and Y. Zheng
We investigated the association between serum visfatin levels and single nucleotide polymorphisms (SNPs; rs61330082, rs2058539) in the visfatin gene and coronary artery calcification (CAC) in patients from Wenzhou, China. CAC patients (N = 206) were divided into two groups: mild CAC (MCAC) and moderate and severe CAC (MSCAC). .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028217
- DOI:
- 10.4238/gmr.15028217
ORMDL3 variants associated with bronchiolitis susceptibility in a Chinese population
Authors: X.T. Liu, L. Ren, L.L. Zhou, Q.Y. Xiao, Y. Deng and E.M. Liu
Recent studies revealed common genetic risks for both viral bronchiolitis and asthma. Genome-wide association studies revealed that rs7216389 in the ORMDL3 gene is associated with childhood asthma. We conducted a case-control study examining the associations between ORMDL3 polymorphisms (rs7216389, rs12603332, and rs11650680) and bronchiolitis susceptibil.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.29.25
- DOI:
- 10.4238/2015.December.29.25
Rapid identification of single nucleotide polymorphisms by fluorescence-based capillary electrophoresis
Authors: Montse Bernat, Esther Titos and Joan Cl� ria
We describe the application of two different fluorescence- based techniques (ddNTP primer extension and single-strand conformation polymorphism (SSCP)) to the detection of single nucleotide polymorphisms (SNPs) by capillary electrophoresis. The ddNTP primer extension technique is based on the extension, in the presence of fluo.. Read More»
- Genet. Mol. Res. 1(1):