Snp
Marker-Assisted elimination of drought-susceptible accessions in upland rice breeding
Authors: Ariadna Faria Vieira, Gabriel Feresin Pantali�£o, Fernanda Martins Abreu, Ricardo Dias Silveira, Ana Letycia Basso Garcia, Leandro Gomide Neves, Rosana Pereira Vianello, Adriano Pereira Castro, Claudio Brondani
Breeding for water-deficit tolerance is fundamental to guarantee the sustainability of upland rice production, mainly due to the possibility of an increased frequency of drought episodes due to climate change. This work aimed to identify single nucleotide polymorphism (SNP) markers, derived from RNA sequencing (RNA-Seq), genom.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039886
- DOI:
- 10.4238/gmr16039886
Prenatal diagnosis of ventricular septal defect and trisomy 7q11.23q21.3 in two fetuses: A case report
Authors: Kai Mu, Li-Sha Chen, Juan Wen, Yi Liu, Na Liu, Dong-Hua Cao
The objective of prenatal diagnosis (PD) is to provide prenatal diagnostic testing services for genetic conditions that enable families to make informed choices consistent with their individual needs and values, and to support them in deal with the outcome of such testing. This case we reported is about two fetuses with ventri.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039878
- DOI:
- 10.4238/gmr16039878
Single Nucleotide Polymorphisms associated with growth and carcass traits located on QTL Regions previously associated with Bovine Respiratory Disease
Authors: S. Mizell, S.L. Miller, A.M. Royer, K.J. Thornton, and M.D. Garcia
The objective of the current study was to evaluate single nucleotide polymorphisms (SNP) for potential growth and carcass trait associations located in two previously described quantitative trait loci (QTL) regions associated with bovine respiratory disease. A population of 323 crossbred steers sired by five purebred sire bree.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039843
- DOI:
- 10.4238/gmr16039843
Protein Z gene variants and risk of Idiopathic Recurrent Pregnancy Loss in Saudi Arabian women
Authors: Walid Zammiti, Sarra Said, Amani Shaman, Faisel Mohammed Abu-Duhier
Background: Protein Z (PZ) is a vitamin K-dependent plasma glycoprotein, it plays a key role in the physiologic inhibition of coagulation by acting as a cofactor in the inactivation of factor Xa. The relationship between PZ gene polymorphisms and pregnancy loss is controversial. To address this, we investigate the association .. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039834
- DOI:
- 10.4238/gmr16039834
Genotypes within the prolactin and growth hormone insulin-like growth factor-I pathways associated with milk production in heat stressed Holstein cattle: Genotypes and milk yield in heat stressed Holstein cows
Authors: Hern�¡ndez-Cordero, M. A. S�¡nchez-Castro, R. Zamorano- Algandar, P. Luna-Nev�¡rez, G. Rinc�³n, J. F. Medrano4, S. E. Speidel, R. M. Enns and M. G. Thomas
The association of single nucleotide polymorphisms (SNPs) within genes of the prolactin (PRL), growth hormone (GH) and insulin-like growth factor-I (IGF1) pathways with 305-day milk yield (MY305) were evaluated in heat-stressed Holstein cows. Ambient temperature and relative humidity were used to calculate a temperature-humidi.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039821
- DOI:
- 10.4238/gmr16039821
Study of genetic variability in pigs after the traditional breeding program
Authors: I.M. Ferreira, G.S. Vieira, T.F. Braga, T.C.F. Silva, M.M. Franco and R.C. Antunes
Molecular markers are tools used to improve genetic gains. The objective of this study was to analyze the security of alleles of molecular marker genes for characteristics of economic interest in a pure population of pigs. After the extraction of DNA from the hair of 272 Large White matrices, the allele and genotype frequency .. Read More»
- Genet. Mol. Res. 16(3):
Interleukin-18 (rs187238) and glucose transporter 4 (rs5435) polymorphisms in Euro-Brazilians with type 1 diabetes
Authors: Y. Al-Lahham, A.K.B. Mendes, E.M. Souza, D. Alberton, F.G.M. Rego, G. Valdameri and G. Picheth
Type 1 diabetes (T1D) is an autoimmune disease with a strong genetic component that has been associated with several genetic loci. Interleukin 18 (IL-18) is a potent proinflammatory cytokine, which is involved in the innate and adaptive immune responses, and in the pathogenesis of various diseases including T1D. Glucose transp.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039755
- DOI:
- 10.4238/gmr16039755
Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle
Authors: P. Saowaphak, M. Duangjinda, S. Plaengkaeo, R. Suwannasing and W. Boonkum
In this study, we estimated the genetic parameters and identified the putative quantitative trait loci (QTL) associated with the length of productive life (LPL), days open (DO), and 305-day milk yield for the first lactation (FM305) of crossbred Holstein dairy cattle. Data comprising 4,739 records collected between 1986 and 20.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029091
- DOI:
- 10.4238/gmr16029091
Polymorphisms in the melatonin receptor gene promoter and their associations with fertility characteristics in buffalo herd in Eastern Amazon
Authors: E.M. Barbosa, B.B. Souza, R.C. Guimar�£es, L.K.N. Silva, J.S.N. Azevedo, E.C. Gon�§alves, H.F.L. Ribeiro, S.T. Rolim Filho and E. Silva Filho
Buffalo production is spreading globally because of its economic advantage. Then, it has become necessary to improve the reproductive and productive efficiency of these animals, as well as to look for genetic factors that increase this efficiency. The objectives of this study were to characterize the promoter region of the mel.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029610
- DOI:
- 10.4238/gmr16029610
Role of XRCC1 and ERCC5 polymorphisms on clinical outcomes in advanced non-small cell lung cancer
Authors: D. Liu, J. Wu, G.Y. Shi, H.F. Zhou and Y. Yu
We aimed to assess the role of polymorphisms of the XRCC1 Arg194Trp, XRCC1 Arg399Gln, ERCC5 His1104Asp, and ERCC5 His46His genes on clinical outcomes of advanced non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy regimens. A total of 378 NSCLC patients were asked to participate within 1 month aft.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.6
- DOI:
- 10.4238/2014.April.17.6