Snp
Leptin (rs7799039) and solute carrier family 30 zinc transporter (rs13266634) polymorphisms in Euro-Brazilian pregnant women with gestational diabetes
Authors: A. Teleginski, M. Welter, H.R. Frigeri, R.R. R�©a, E.M. Souza, D. Alberton, F.G.M. Rego, G. Picheth
Leptin (LEP), a protein that plays a fundamental role in the metabolism of energy reserves, and the solute carrier family 30 A8 zinc transporter (SLC30A8) have been consistently associated with diabetes. Women with gestational diabetes are at moderate risk of developing diabetes type 1 and 2 after pregnancy, in addition to com.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019515
- DOI:
- 10.4238/gmr16019515
Growth hormone polymorphisms and growth traits in Chinese Tibetan sheep Ovis aries
Authors: Y.C. Han, Y.G. Sun and Q. Li
Growth hormone (GH) plays an important role in promoting growth, protein and muscle accretion, and fat catabolism, suggesting that GH is a potential candidate gene affecting growth traits in vertebrates. In this paper, polymorphisms in GH were investigated in 632 Chinese Tibetan sheep, by using DNA sequencing. Three single nucleotide polymorphisms were id.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038397
- DOI:
- 10.4238/gmr.15038397
Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene
Authors: Y.F. Liu, L.S. Zan, W.T. Cui, Y.P. Xin, Y. Jiao and K. Li
Cyclin-dependent kinase 6 (CDK6) is a key element of D-type cyclin holoenzymes. It is involved in the regulation of the G1-phase of the cell cycle and is considered to be an important candidate gene for selection of body measurement traits through marker-assisted selection. We cloned the promoter sequence of this gene in bovin.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1466
- DOI:
- 10.4238/vol10-3gmr1466
Molecular characterization, polymorphism of the ACOX1 gene and association with ultrasound traits in Bos taurus
Authors: Y. Jiao, L.S. Zan, Y.F. Liu and H.B. Wang
Acyl-coenzyme A oxidase 1 (ACOX1) is the first enzyme in peroxisomal fatty acid β-oxidation; it is rate-limiting and plays a key role in fatty acid metabolism and fat deposition. ACOX1 is an important candidate gene for meat quality selection through marker-assisted selection. Genomic structural analysis showed that bovin.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1036
- DOI:
- 10.4238/vol10-3gmr1036
Single nucleotide polymorphisms in CAPN and leptin genes associated with meat color and tenderness in Nellore cattle
Authors: L.F.B. Pinto, J.B.S. Ferraz, V.B. Pedrosa, J.P. Eler, F.V. Meirelles, M.N. Bonin, F.M. Rezende, M.E. Carvalho, D.C. Cucco and R.C.G. Silva
We analyzed single nucleotide polymorphisms in calpain, leptin, leptin receptor, and growth hormone receptor genes and their association with color, drip and cooking losses of longissimus muscle at 7, 14 and 21 days postmortem in 638 purebred Nellore bulls slaughtered between 22 and 26 months of age. Meat samples were vacuum-p.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1263
- DOI:
- 10.4238/vol10-3gmr1263
A case-control study indicates that the TRIB1 gene is associated with pancreatic cancer
Authors: X.X. Lu, J.J. Hu, Y. Fang, Z.T. Wang, J.J. Xie, Q. Zhan, X.X. Deng, H. Chen, J.B. Jin, C.H. Peng, J. Liu, H.W. Li and B.Y. Shen
Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues that form the pancreas. To investigate whether the tribbles homolog 1 (Drosophila) gene (TRIB1) is associated with pancreatic cancer in the Chinese Han population, we conducted this case-control study and genotyped.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.30
- DOI:
- 10.4238/2014.August.7.30
Are bone mineral density loci associated with hip osteoporotic fractures? A validation study on previously reported genome-wide association loci in a Chinese population
Authors: Y. Guo, J.-T. Wang, H. Liu, M. Li, T.-L. Yang, X.-W. Zhang, Y.-Z. Liu, Q. Tian and H.-W. Deng
Osteoporosis is a heritable disease characterized mainly by low bone mineral density (BMD) and/or osteoporotic fractures (OF). Most genome-wide association studies on osteoporosis have focused on BMD, whereas little effort has been expended to identify genetic variants directly linked to OF. To determine whether BMD-loci are a.. Read More»
- Genet. Mol. Res. 11(1):
- http://dx.doi.org/2012.January.31.1
- DOI:
- http://dx.doi.org/10.4238/2012.January.31.1
Association between IGF2 and CYP21 gene polymorphisms and characteristics of economic interest in Nellore cattle
Authors: A. Martins da Silva, A.F.L. Rios, E.S. Ramos, R.B. L�´bo, H.N. Oliveira and M.A.R. de Freitas
We analyzed two single nucleotide polymorphisms (SNPs) of the IGF2 and CYP21 genes in Nellore cattle participating in the Brazilian Animal Breeding Program. The SNPs were found in exon 6 of the IGF2 (insulin-like growth factor 2) gene (RFLP/MboII) as well as in the promoter region of the CYP21 (steroid 21-hydroxylase) gene (RF.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1184
- DOI:
- 10.4238/vol10-3gmr1184
Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China
Authors: J. Li, Y. Cun, W.R. Tang, Y. Wang, S.N. Li, H.R. Ouyang, Y.R. Wu, H.J. Yu and C.J. Xiao
Endothelial nitric oxide synthase (eNOS) plays an important role in maintaining blood pressure homeostasis and vascular integrity. Polymorphisms in the eNOS gene have been found to be associated with hypertension in different human populations, including Northern and Southern Chinese Han populations. To examine the relationshi.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1160
- DOI:
- 10.4238/vol10-3gmr1160
Assessment of genetic diversity in lentils (Lens culinaris Medik.) based on SNPs
Authors: R. Basheer-Salimia, B. Camilli, S. Scacchi, E. Noli andM. Awad
This study is the first attempt to establish an SNP database for the purpose of estimating the genetic diversity and relatedness of Palestinian lentil genotypes. A total of 14 lentil accessions (11 local, two supplied by ICARDA, and one introduced from Italy) were investigated. By sequencing two genes, lectin and lipid transfer protein 5 (LTP5), four SNPs.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.4
- DOI:
- 10.4238/2015.June.1.4