Snp
Molecular authentication of multi-species honeysuckle tablets
Authors: C. Jiang*, Y. Yuan*, M. Chen and L. Huang
Authenticating multi-species original raw materials in commercial formulations is difficult. Jin Yin Hua and Shan Yin Hua, both classified as raw honeysuckle materials in the Chinese Pharmacopoeia, are used in various medicines. Differentiating one variety from another is difficult based on chemical analysis. We developed molecular authentication of multi.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.22.2
- DOI:
- 10.4238/2013.October.22.2
Association study of polymorphisms between the Radixin gene and rheumatoid arthritis in a Korean population
Authors: H.-K. Kim, J.-S. Joo, H.-Y Lee, J.-T. Kwon, D.-R. Sohn, S.-J. Hong and H.-J. Kim
Radixin (RDX) is part of the ezrin-radixin-moesin (ERM) protein family. It functions as a membrane-cytoskeletal linker in actin-rich cell surface structures and is thought to be essential for cortical cytoskeleton organization, cell motility, adhesion, and proliferation. An increase in phosphorylated ERM in fibroblast-like syn.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.9.14
- DOI:
- http://dx.doi.org/10.4238/2014.May.9.14
Molecular cloning and characterization of KISS1 promoter and effect of KISS1 gene mutations on litter size in the goat
Authors: X.P. An, P. Han, J.X. Hou, H.B. Zhao, Y. Yan, T. Ma, F. Fang, F.X. Meng, Y.X. Song, J.G. Wang and B.Y. Cao
Kisspeptins, the product of the KISS1 gene, play an essential role in the regulation of reproductive functions, acting primarily at the hypothalamic level of the gonadotropic axis. We detected polymorphisms of the goat KISS1 gene in 723 individuals from three goat breeds (Xinong Saanen, Guanzhong, and Boer) by DNA pooling, PCR-RFLP, and DNA sequencing met.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.13
- DOI:
- 10.4238/2013.February.28.13
Novel SNPs in the exon region of bovine DKK4 gene and their association with body measurement traits in Qinchuan cattle
Authors: J.B. Gao, Y.K. Li, N. Yang, X.H. Ma, C. Adoligbe, B.J. Jiang, C.Z. Fu,G. Cheng and L.S. Zan
The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) of bovine Dickkopf homolog 4 (DKK4) are associated with body measurement traits in Qinchuan cattle. By using PCR-SSCP technology and DNA sequencing, we discovered 5 DKK4 SNPs in Qingchuan cattle, including -65G>A and -77G>T in the 5êÂ?Â?-untranslated region, 1532C.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.30
- DOI:
- 10.4238/2013.February.28.30
Association between the Rs3087243 polymorphism and risk for diabetes: a meta-analysis
Authors: J. Liu and H.-X. Zhang
The aim of this study was to evaluate the association between the rs3087243 polymorphism of the cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene and the risk of type 1 diabetes mellitus (T1D). A comprehensive meta-analysis of case-control studies was conducted to determine the association between the rs3087243 polymorphism (CT60A/G) and T1D and a.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.6.1
- DOI:
- 10.4238/2013.December.6.1
Frequencies of -308G/A (TNFA) and -509C/T (TGFB1) polymorphisms in sickle cell anemia patients from Brazil
Authors: L.S. Torres, E. Belini Junior, D.G. Silva, C.L. Lobo, M.A. Ruiz and C.R. Bonini-Domingos
Sickle cell anemia is an affection that causes chronic inflammation, with consequences for vaso-occlusion, oxidative stress and cytokine production. Genetic polymorphisms in markers involved in this process can modulate the inflammatory response, including polymorphisms -308G/A of TNFA (tumor necrosis factor alpha) and -509C/T of TGFB1 (transforming growt.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.16.1
- DOI:
- 10.4238/2013.December.16.1
Single nucleotide polymorphism screening, molecular characterization, and evolutionary aspects of chicken Piwi genes
Authors: H.Z. Wang, T. Ma, G.B. Chang, F. Wan, X.P. Liu, L. Lu, L. Xu, J. Chen and G.H. Chen
The P-element-induced wimpy testis (Piwi) gene is involved in germline stem cell self-renewal, meiosis, RNA silencing, and transcriptional regulation. Piwi genes are relatively well conserved in many species, but their function in poultry species is unclear. In this study, Piwi genes were sequenced u.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.45
- DOI:
- 10.4238/2015.November.18.45
Novel single nucleotide polymorphisms of the bovine methyltransferase 3b gene and their association with meat quality traits in beef cattle
Authors: X. Liu, X.Y. Guo, X.Z. Xu, M. Wu, X. Zhang, Q. Li, P.P. Ma, Y. Zhang, C.Y. Wang, F.J. Geng, C.H. Qin, L. Liu, W.H. Shi, Y.C. Wang and Y. Yu
DNA methylation is essential for adipose deposition in mammals. We screened SNPs of the bovine DNA methyltransferase 3b (DNMT3b) gene in Snow Dragon beef, a commercial beef cattle population in China. Nine SNPs were found in the population and three of six novel SNPs were chosen for genotyping and analyzing a possible association with 16 meat quality trai.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.29.1
- DOI:
- 10.4238/2012.June.29.1
Polymorphisms of PRLR and FOLR1 genes and association with milk production traits in goats
Authors: J.X. Hou, F. Fang, X.P. An, Y. Yan, T. Ma , P. Han , F.X. Meng , Y.X. Song , J.G. Wang and B.Y. Cao
We investigated the polymorphisms of PRLR and FOLR1 genes in Xinong Saanen, Guanzhong, and Boer goat breeds by DNA sequencing and PCR–RFLP. Two novel SNPs were identified: KC109741: g.62130C>T in the 3êÂ?Â?-UTR of goat gene PRLR, and KC136296: g.7884A>C in exon 3 of goat gene FOLR1. In the three goat breeds, the p.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.1
- DOI:
- 10.4238/2014.January.24.1
A new single nucleotide polymorphism in the ryanodine gene of chicken skeletal muscle
Authors: A.A. Droval, E. Binneck, S.R.R. Marin, F.G. Pai�£o1, A. Oba, A.L. Nepomuceno and M. Shimokomaki
Some genes affect meat quality in chickens. We looked for polymorphisms in the Gallus gallus α-RyR gene (homologous to RyR 1) that could be associated with PSE (pale, soft and exudative) meat. Because RyR genes are over 100,000 bp long and code for proteins with about 5000 amino acids, primers were designed to amplify a .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.3.4
- DOI:
- 10.4238/2012.April.3.4