Snp
Red Sindhi cattle in Brazil: population structure and distribution
Authors: J.C.C. Panetto, M.V.G.B. Silva, R.M.H. Leite, M.A. Machado,F.A.T. Bruneli, D.R.L. Reis, M.G.C.D. Peixoto, R.S. Verneque
The Red Sindhi cattle breed was imported to Brazil in small numbers. Nowadays, the herds of this breed are distributed in the Northeast, Southeast and Midwest regions of the country. In this study, DNA samples of animals originating from 15 herds in the Northeast and Southeast regions have been analyzed to obtain the ancestry .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019501
- DOI:
- 10.4238/gmr16019501
Association of CD14 G(-1145)A and C(-159)T polymorphisms with reduced risk for tuberculosis in a Chinese Han population
Authors: M.Y. Zhao Y. Xue Z.Q. Zhao F.J. Li D.P. Fan L.L. Wei X.J. Sun X. Zhang X.C. Wang Y.X. Zhang J.C. Li
Although the role of CD14 in mediating signals from Toll-like receptors to recognize Mycobacterium tuberculosis is known, how polymorphisms in this gene affect the susceptibility to develop tuberculosis are still not clear. We examined whether single nucleotide polymorphisms at positions -1145 and -159 in the promoter region of the CD14 gene are associate.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.September.25.11
- DOI:
- 10.4238/2012.September.25.11
Regularized quantile regression applied to genome-enabled prediction of quantitative traits
Authors: M. Nascimento, F.F. e Silva, M.D.V. de Resende, C.D. Cruz,A.C.C. Nascimento, J.M.S. Viana, C.F. Azevedo, L.M.A. Barroso
Genomic selection (GS) is a variant of marker-assisted selection, in which genetic markers covering the whole genome predict individual genetic merits for breeding. GS increases the accuracy of breeding values (BV) prediction. Although a variety of statistical models have been proposed to estimate BV in GS, few methodologies h.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019538
- DOI:
- 10.4238/gmr16019538
Lack of association between TYK2 and STAT3 genes and Crohn�s disease in the Malaysian population
Authors: L.H. Lian T.P. Lau V.L. Lee W.S. Lee I. Hilmi K.L. Goh K.H. Chua
This study aimed to investigate the potential association of TYK2 and STAT3 genes with the susceptibility to Crohn’s disease (CD) among Malaysians. DNA samples were obtained from 80 CD patients and 100 healthy controls. Polymerase chain reaction-restriction fragment length polymorphism methods were employed for genotyping, followed by statistical an.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.9
- DOI:
- 10.4238/2013.January.24.9
SNP detection using RNA-sequences of candidate genes associated with puberty in cattle
Authors: S.J. Coleman, S.E. Speidel, R.M. Enns, A. Islas-Trejo, J.F. Medrano, S.S. Moore, M.R.S. Fortes, L.T. Nguyen, B. Venus, I.S.D.P. Diaz,F.R.P. Souza, L.F.S. Fonseca, F. Baldi, L.G. Albuquerque, M.G. Thomas, H.N. Oliveira
Fertility traits, such as heifer pregnancy, are economically important in cattle production systems, and are therefore, used in genetic selection programs. The aim of this study was to identify single nucleotide polymorphisms (SNPs) using RNA-sequencing (RNA-Seq) data from ovary, uterus, endometrium, pituitary gland, hypothala.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019522
- DOI:
- 10.4238/gmr16019522
Polymorphisms in FGFBP1 and FGFBP2 genes associated with carcass and meat quality traits in chickens
Authors: A.M. FelÃ?Âcio C. Boschiero J.C.C. Balieiro M.C. Ledur J.B.S. Ferraz A.S.A.M.T. Moura L.L. Coutinho
In the past, the focus of broiler breeding programs on yield and carcass traits improvement led to problems related to meat quality. Awareness of public concern for quality resulted in inclusion of meat quality traits in the evaluation process. Nevertheless, few genes associated with meat quality attributes are known. Previous studies mapped quantitative .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.13
- DOI:
- 10.4238/2013.January.24.13
Four SNPs of insulin-induced gene 1 associated with growth and carcass traits in Qinchuan cattle in China
Authors: Y. Liu, X.L. Liu, H. He and Y.L. Gu
The insulin-induced gene 1 (Insig-1) is a regulator of lipid metabolism and plays an important role in the sterol-mediated regulation of SREBP, SCAP and HMG-CoA reductase. We used PCR-RFLP and DNA sequencing to detect polymorphisms of the Insig-1 gene in 215 individuals of the Qinchuan cattle breed. Four SNPs [4366(A>G), 45.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.8.3
- DOI:
- 10.4238/2012.May.8.3
Molecular cloning and single nucleotide polymorphism analysis of IGF2a genes in the common carp (Cyprinus carpio)
Authors: S.Y. Su, Z.J. Dong, J.Q. Qu, Z.Y. Liang, J.Q. Zhang, L.X. Ma, W. Liu, P. Xu and X.H. Yuan
We studied whether two IGF2 transcripts in common carp are similar to those found in zebrafish. The full-length IGF2a cDNA contains a 5'-terminal untranslated region (UTR) of 105 bp, a 3'-terminal UTR of 1358 bp and an open reading frame of 612 bp, which encodes a 206-amino acid protein. A 6614-bp full-length IGF2a DNA molecul.. Read More»
- Genet. Mol. Res. 11(2):
- 0.4238/2012.May.15.3
- DOI:
- 0.4238/2012.May.15.3
More severe clinical course of cardiovascular dysfunction in intensive care unit patients with the 894TT eNOS genotype
Authors: L.R. Fraga F.J.O. Paludo A.J.G. B�³s J.L.S. Ferraro F.S. Dias C.S. Alho
The endothelial nitric oxide synthase (eNOS) plays an important homeostatic role in the cardiovascular system (CVS) by maintaining appropriate blood pressure through production of nitric oxide. The 894TT genotype of 894G>T (Glu298Asp, rs1799983), a polymorphic variant of eNOS, has been associated with several vascular diseases. On the basis of this str.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.February.27.5
- DOI:
- 10.4238/2013.February.27.5
Manipulation of components that control feeding behavior in Drosophila melanogaster increases sensitivity to amino acid starvation
Authors: J.D. Slade and B.E. Staveley
Feeding is a complex behavior that is regulated by several internal mechanisms. Neuropeptides are able to survey quantities of stored energy and inform the organism if nutrient intake is required. In addition to this homeostatic regulation, a post-feeding reward system positively reinforces feeding. Slight adjustments to either system can tilt the balance.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017489
- DOI:
- 10.4238/gmr.15017489