Snp
Characterization of SNPs in strawberry cultivars in China
Authors: A.J. Ge J. Han X.D. Li M.Z. Zhao H. Liu Q.H. Dong J.G. Fang
Single nucleotide polymorphisms (SNPs) occur at high frequencies in both plant and animal genomes and can provide broad genome coverage and reliable estimates of genetic relationships. The availability of expressed sequence tag (EST) data has made it feasible to discover SNPs. DNA analysis is crucial in genetic studies not only for strawberry breeding progra.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.7.2
- DOI:
- 10.4238/2013.March.7.2
Study of lipid metabolism-related genes as candidate genes of sexual precocity in Nellore cattle
Authors: M.M. Dias, F.R.P. Souza, L. Takada, F.L.B. Feitosa, R.B. Costa,I.D.P.S. Diaz, D.F. Cardoso, R.L. Tonussi, F. Baldi,L.G. Albuquerque and H.N. Oliveira
The objective of this study was to identify associations between known polymorphisms in genes related to adipose tissue and sexual precocity in Nellore cattle. A total of 1689 precocious and non-precocious heifers belonging to farms participating in Conexão Delta G breeding program were studied. SNPs from the Illumina High-Density Bovine SNP BeadCh.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.16.7
- DOI:
- 10.4238/2015.January.16.7
Analysis of polymorphisms in codons 11, 72 and 248 of TP53 in Brazilian women with breast cancer
Authors: B.C. Almeida1, J.P.F.O. Kleine1, C.M. Camargo-Kosugi1,2, M.R. Lisboa1,C.N. Fran�§a3, J.P. Fran�§a4 and I.D.C.G. Silva1
The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53*11, TP53*72, and TP53*248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 p.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017055
- DOI:
- 10.4238/gmr.15017055
SNPs at 3'-UTR of the bovine CDIPT gene associated with Qinchuan cattle meat quality traits
Authors: C.Z. Fu H. Wang C.G. Mei J.L. Wang B.J. Jiang X.H Ma H.B. Wang G. Cheng L.S. Zan
As the most ancient member of the wheat gluten family, the Ã?³-gliadin genes are suitable for phylogenetic analysis among wheat and related species. Species in the grass genus Dasypyrum have been widely used for wheat cross breeding. However, the genomic relationships among Dasypyrum species have been little studied. We isolated 22 novel Ã?³-gliadin gene s.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.13.6
- DOI:
- 10.4238/2013.March.13.6
Frequency of MDR1 single nucleotide polymorphisms in a Jordanian population, including a novel variant
Authors: O.F. Khabour K.H. Alzoubi S.I. Al-Azzam N.M. Mhaidat
The multidrug resistance gene (MDR1 or ABCB1) codes for P-glycoprotein, which plays an important role in regulating absorption, distribution, and elimination of drugs. We examined MDR1 gene variants in 100 unrelated subjects from various regions of Jordan. The MDR1 gene was scanned using direct sequencing. Six rare variants in MDR1 were detected, includin.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.13.9
- DOI:
- 10.4238/2013.March.13.9
Polymorphism E23K (rs5219) in the KCNJ11 gene in Euro-Brazilian subjects with type 1 and 2 diabetes
Authors: S.W. Souza, L.P. Alcazar, P.A. Arakaki, I.C.R. Santos-Weiss, D. Alberton, G. Picheth and F.G.M. Rego
Insulin secretion is regulated by ATP-sensitive potassium channels (KATP). The potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) gene, located on chromosome 11p15.1, encodes the subunit Kir6.2 that forms the pore region of KATP channels in pancreatic β-cells. Among the single nucleotide polymorphisms .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029543
- DOI:
- 10.4238/gmr16029543
Genome-wide association analysis of body conformation traits in Mexican Holstein cattle using a mix of sampled and imputed SNP genotypes
Authors: M.E. Gonz�¡lez, V.M. Gonz�¡lez, M.F. Monta�±o, G.E. Medina,P. Mahadevan, C. Villa and R. Villa
In arid and semi-arid zones, animal health and production are closely correlated with body conformation traits. These selected traits, in turn, allow livestock to adapt unfavorable soil and environmental conditions. The primary objective of this study was to perform a genome-wide association analysis for a set of sampled and i.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029597
- DOI:
- 10.4238/gmr16029597
A novel method for identifying SNP disease association based on maximal information coefficient
Authors: H.M. Liu, N. Rao, D. Yang, L. Yang, Y. Li and F. Ou
To improve single-nucleotide polymorphism (SNP) association studies, we developed a method referred to as maximal information coefficient (MIC)-based SNP searching (MICSNPs) by employing a novel statistical approach known as the MIC to identify SNP disease associations. MIC values varied with minor allele frequencies of SNPs and the odds ratios for diseas.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.19.7
- DOI:
- 10.4238/2014.December.19.7
Association between polymorphisms of the CRH and POMC genes with economic traits in Korean cattle (Hanwoo)
Authors: J. Seong and H.S. Kong
The corticotrophin-releasing hormone (CRH) and proopiomelanocortin (POMC) genes are considered to play an important role in the growth and development of mammals. In this study, the bovine CRH and POMC genes were characterized to detect genetic variation at these loci in relation to economic traits in Korean cattle (Hanwoo). Nine single nucleotide polymor.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.8.2
- DOI:
- http://dx.doi.org/10.4238/2015.September.8.2
Hsp70 gene polymorphisms in farmed marine shrimp Litopenaeus vannamei populations exposed to white spot disease and infectious myonecrosis
Authors: A.L. Ferreira Jr, R. Maggioni, D. Concei�§�£o, L.M. Perazzolo and R.L. Petersen
Single nucleotide polymorphisms (SNPs) are the best genetic markers for associative studies of the immune system in invertebrates. In the marine shrimp Litopenaeus vannamei, SNPs linked to disease resistance have been reported for some genes, such as hemocyanin, anti-lipopolysaccharide factor, and heat-shock protein 70 (Hsp70).. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029668
- DOI:
- 10.4238/gmr16029668