Snp
A single nucleotide polymorphism of the TNRC9 gene associated with breast cancer risk in Chinese Han women
Authors: F. Chen, J. Zhou, Y. Xue, S. Yang, M. Xiong, Y. Liand Q. Liu
A single nucleotide polymorphism (SNP) in the TNRC9 gene was identified as a breast cancer susceptibility genetic variant in recent genome-wide association studies of women of European ancestry. We investigated whether TNRC9 polymorphisms are associated with risk of breast cancer in Chinese women of the Han nationality. We gen.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.10.9
- DOI:
- 10.4238/2014.January.10.9
Genetic divergence among Psidium accessions based on single nucleotide polymorphisms developed for Eucalyptus
Authors: S.R. Costa and C.A.F. Santos
The goal of this study was to analyze the genetic divergence among Psidium species accessions based on SNPs developed for Eucalyptus. Fifty-three Psidium accessions, including 47 P. guajava, were genotyped with EUCHIP60K. The dendrogram similarity ranged from 0.58 to 1.00, with a cophenetic value of 0.97. Five groups were iden.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029566
- DOI:
- 10.4238/gmr16029566
Identification and characterization of RFRP gene in pigs and its association with reproductive traits
Authors: M.X. Fang, Y.S. Huang, J. Ye, W. Zhang, Y. Li and Q.H. Nie
RFamide-related peptide (RFRP) gene is a crucial gene of the hypothalamo-pituitary-gonadal axis and plays an important role in reproduction regulation. This study aimed to clone and characterize the pig RFRP gene. We obtained a 645-bp cDNA of pig RFRP gene comprising a 546-bp open reading frame, which encoded a peptide of 188 .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.14.8
- DOI:
- 10.4238/2014.January.14.8
Effects of polymorphisms in the XRCC1, XRCC3, and XPG genes on clinical outcomes of platinum-based chemotherapy for treatment of non-small cell lung cancer
Authors: Z.Y. Jin, X.T. Zhao, L.N. Zhang, Y. Wang, W.T. Yue and S.F. Xu
This study aimed to investigate the effects of single-nucleotide polymorphisms (SNPs) XRCC1 Arg194Trp, XRCC1 Arg280His, XRCC1 Arg399Gln, XRCC3 Thr241Met, XPG His104Asp, and XPG His46His in genes involved in the DNA-repair pathway on the outcomes of platinum-based chemothera.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.March.31.13
- DOI:
- 10.4238/2014.March.31.13
Polymorphisms in the DGAT1 gene in buffaloes (Bubalus bubalis) in the Amazon
Authors: C.S. Silva, E. Silva Filho, A.S. Matos, A.S. Schierholt, M.R. Costa, L.C. Marques, J.S. Costa, R.L. Sales, M.R. Figueir�³ and J.R.F Marques
Water buffaloes (Bubalus bubalis) are quite well adapted to climatic conditions in the Amazon, and in this biome, they are noted for the considerable amount of meat and milk they produce and how hard they are able to work. Because of a lack of research dedicated to improving the rearing of buffaloes in the Amazon, the objective of this study was to geneti.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038720
- DOI:
- 10.4238/gmr.15038720
Identification of SNPs in growth-related genes in Colombian creole cattle
Authors: R. Martinez, J.F. Rocha, D. Bejarano, Y. Gomez, Y. Abuabara and J. Gallego
Colombian creole cattle have important adaptation traits related to heat tolerance and reproductive and productive efficiency. Romosinuano (ROMO) and Blanco Orejinegro (BON) are the most common breeds used by Colombian cattle breeders. Growth traits are of prime importance in these animals, which are mainly raised for beef production. Genes encoding growt.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038762
- DOI:
- 10.4238/gmr.15038762
Polymorphisms in the ovine myostatin gene are associated with birth weight but not with weight gain in Iranian Makoei sheep
Authors: M. Farhadian A. Hashemi K. Mardani R. Darvishzadeh S. Jafari
Myostatin, a transforming growth factor-beta superfamily member, has been well documented as a negative regulator of muscle growth and development. Myostatin, which has 376 amino acids, is synthesized as a precursor protein. Polymorphism of the myostatin gene in Makoei sheep was investigated by PCR and single-strand conformation polymorphism technique (SSCP).. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.4.4
- DOI:
- 10.4238/2012.October.4.4
Association of RUNX2 and TNFSF11 genes with production traits in a paternal broiler line
Authors: N.V. Grupioni, N.B. Stafuzza, A.B. Carvajal, A.M.G. Ibelli, J.O. Peixoto, M.C. Ledur, D.P. Munari
Intense selection for production traits has improved the genetic gain of important economic traits. However, selection for performance and carcass traits has led to the onset of locomotors problems and decreasing bone strength in broilers. Thus, genes associated with bone integrity traits have become candidates for genetic stu.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019443
- DOI:
- 10.4238/gmr16019443
Identification of 19 loci for reproductive traits in a local Chinese chicken by genome-wide study
Authors: Q.C. Fan, P.F. Wu, G.J. Dai, G.X. Zhang, T. Zhang, Q. Xue,H.Q. Shi, J.Y. Wang
Reproductive traits have long been studied and have an important influence on chicken breeding. To identify quantitative trait loci affecting reproductive traits, a genome-wide analysis of a Chinese chicken breed was performed to analyze age at first egg body weight at first egg, first egg weight, egg weight at the age of 300 .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019431
- DOI:
- 10.4238/gmr16019431
Genotyping of SNPs associated with meat tenderness: comparison of two PCR-based methods
Authors: L.E. L�³pez-Rojas, L. Pati�±o-Cadavid, A. L�³pez-Herrera and J.J. Echeverri-Zuluaga
Single nucleotide polymorphisms (SNPs) carried in calpain (CAPN1), calpastatin (CAST), and leptin (LEP) genes are associated with meat tenderness. Due to the economic importance of this meat quality attribute, the development of fast, reliable, and affordable methods to identify bovine carriers of favorable alleles is of great.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029635
- DOI:
- 10.4238/gmr16029635