Snp
A multiplex single-base extension protocol for genotyping Cdx2, FokI, BsmI, ApaI, and TaqI polymorphisms of the vitamin D receptor gene
Authors: Lins TCL, Nogueira LR, Lima RM, Gentil P, Oliveira RJ and Pereira RW
The well-described role of the vitamin D endocrine system in bone metabolism makes its receptor a widely investigated candidate gene in association studies looking for the genetic basis of complex bone-related phenotypes. Most association studies genotype five polymorphic sites along the gene using PCR-RFLP and allele-specific.. Read More»
- Genet. Mol. Res. 6(2):
A novel polymorphism of the MYPN gene and its association with meat quality traits in Bos taurus
Authors: Y. Jiao, L.S. Zan, Y.F. Liu, H.B. Wang and B.L. Guo
Myopalladin (MYPN) is a multifunctional protein that maintains sarcomeric integrity and regulates Z-line structure. It is an important candidate gene for meat quality selection through marker-assisted selection. Using PCR-RFLP technology, we discovered a single-nucleotide polymorphism (SNP) (A1795G in exon 9) of the MYPN gene... Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr906
- DOI:
- 10.4238/vol9-3gmr906
Characterization of variation in the canine suppressor of cytokine signaling-2 (SOCS2) gene
Authors: Rincon G, Young AE, Bannasch DL and Medrano JF
Suppressor of cytokine signaling 2 (SOCS2) is a negative regulator of growth hormone signaling. The deletion of SOCS2 in mice results in a 30-50% increase in post-natal growth. In an effort to identify polymorphisms in the SOCS2 gene that may be associated with body size in dogs, we characterized the canine SOCS2 gene and anal.. Read More»
- Genet. Mol. Res. 6(1):
Associations of DNA polymorphisms in growth hormone and its transcriptional regulators with growth and carcass traits in two populations of Brangus bulls
Authors: Thomas MG, Enns RM, Shirley KL, Garcia MD, Garrett AJ, and Silver GA
Sequence polymorphisms in the growth hormone (GH) gene and its transcriptional regulators, Pit-1 and Prop-1, were evaluated for associations with growth and carcass traits in two populations of Brangus bulls Chihuahuan Desert Rangeland Research Center (CDRRC, N = 248 from 14 sires) and a cooperating breeding program (COOP, N =.. Read More»
- Genet. Mol. Res. 6(1):
Association between the rs3795879 G/A polymorphism of the SERPINE2 gene and chronic obstructive pulmonary disease: a meta-analysis
Authors: D.B. Tian, S.X. Cai, G.C. Pan, Y.F. Zhang and J.H. Xiao
The present study aimed to investigate the effects of the rs3795879 polymorphism of the SERPINE2 gene on the development of chronic obstructive pulmonary disease (COPD) based on a systematic meta-analysis. An extensive literature search was performed to retrieve previously published case-control studies on the polymorphisms of SERPINE2 in COPD patients. O.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.14.18
- DOI:
- 10.4238/2015.July.14.18
Lack of association between SNP rs3914132 of the RELN gene and otosclerosis in India
Authors: S. Priyadarshi, K.C. Panda, A.K. Panda and P.V. Ramchander
Otosclerosis (MIM 166800) is primarily a metabolic bone disorder of the otic capsule, which leads to bony fixation of the stapedial footplate in the oval window; it is among the most common causes of acquired hearing loss. The etiology of this disease is largely unknown, although epidemiological studies suggest the involvement.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr890
- DOI:
- 10.4238/vol9-3gmr890
Analysis of �Fuji� apple somatic variants from next-generation sequencing
Authors: H.S. Lee1, G.H. Kim1, S.I. Kwon2, J.H. Kim2, Y.S. Kwon2 and C. Choi1
The domesticated apple (Malus x domestica Borkh.) is a major fruit crop of temperate regions of the world. ‘Fuji’ apple (Ralls Genet x Delicious), a famous apple cultivar in Korea, has been very popular since its promotion in Japan in 1958. ‘Fuji’ and its bud mutant cultivars possess variable levels of genetic diversity. Nonetheles.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038185
- DOI:
- 10.4238/gmr.15038185
Genetic and molecular characterization of multiflorous spikelet in oat
Authors: C.M. Zimmer, I.P. Ubert, K. Pellizzaro, L.C. Federizzi, I.C. Nava
Multiflorous spikelets are found in several grass species of agricultural and economic interest. In oat, this morphological characteristic is associated with the production of naked grains. Although many genetic studies have been performed over the past century, the inheritance of the multiflorous spikelet trait is not fully u.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019588
- DOI:
- 10.4238/gmr16019588
Identification of SNPs located on BTA 6 and BTA 20 significantly associated with bovine respiratory disease in crossbred cattle
Authors: S.L. Miller, S. Mizell, R. Walker, T. Page and M.D. Garcia
The objective of the present study was to evaluate single nucleotide polymorphisms (SNPs) located in two quantitative trait locus (QTL) regions (BTA 6 and BTA 20) that are associated with bovine respiratory disease (BRD). A population of 323 crossbred steers sired by five purebred sire breeds during 2010-2013 (Angus, Braford, .. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048861
- DOI:
- 10.4238/gmr.15048861
Variants -250G/A and -514C/T in the LIPC gene are associated with hypertensive disorders of pregnancy in Chinese womenc
Authors: H. Lin, Z. Yin, X.Y. Yu, N. Lin, Y. Lin, J. Chen, Y.Z. Chen, K.P. Lu and H.K. Liu
We examined the influence of the promoter polymorphisms -250G/A (rs2070895) and -514C/T (rs1800588) in the human hepatic lipase (LIPC) gene on dyslipidemia and hypertensive disorders complicating pregnancy (HDCP) in a Chinese population. Clinically defined HDCP patients (N = 321) and healthy pregnant women (N = 331) w.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.28
- DOI:
- 10.4238/2014.August.7.28